Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00112  |
| T6SS type | Type i3 |
| Strain | Burkholderia thailandensis E264 |
| Replicon (RefSeq) | chromosome II (NC_007650) |
| Location | 303044..334482 |
| Function | - |
| Comment | - |
| References | [1] Russell AB et al (2012) A widespread bacterial type VI secretion effector superfamily identified using a heuristic approach. Cell Host Microbe. 11(5):538-49. [PudMed:22607806] [2] Schwarz S et al (2010) Burkholderia type VI secretion systems have distinct roles in eukaryotic and bacterial cell interactions. PLoS Pathog. 6(8):e1001068. [PudMed:20865170] |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | FHA | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| BTH_RS01280 | 299015..299911 | - | 897 | WP_011400849.1 | LysR family transcriptional regulator | ||
| BTH_RS01285 | 300115..300819 | + | 705 | WP_009894996.1 | SDR family oxidoreductase | ||
| BTH_RS01290 | 301071..303068 | + | 1998 | WP_009894998.1 | DUF3857 and transglutaminase domain-containing protein | ||
| T6CP011371 | FHA | BTH_RS01295 (tagH) | 303044..304489 | - | 1446 | WP_009895000.1 | type VI secretion system-associated FHA domain protein TagH |
| BTH_RS01300 | 304544..304942 | - | 399 | WP_009907141.1 | TssQ family T6SS-associated lipoprotein | ||
| T6CP001049 | TssJ | BTH_RS01305 (tssJ) | 305598..306116 | + | 519 | WP_009895004.1 | type VI secretion system lipoprotein TssJ |
| T6CP001050 | TssK | BTH_RS01310 (tssK) | 306113..307519 | + | 1407 | WP_009895006.1 | type VI secretion system baseplate subunit TssK |
| T6CP001051 | TssL | BTH_RS01315 | 307535..308848 | + | 1314 | WP_009895008.1 | DotU family type VI secretion system protein |
| T6CP001052 | TssM | BTH_RS01320 (tssM) | 308851..312480 | + | 3630 | WP_009895010.1 | type VI secretion system membrane subunit TssM |
| BTH_RS01325 (tagF) | 312477..313352 | + | 876 | WP_009895012.1 | type VI secretion system-associated protein TagF | ||
| BTH_RS01330 | 313510..316143 | + | 2634 | WP_009895014.1 | protein kinase | ||
| T6CP001053 | TssA | BTH_RS01335 (tssA) | 316196..317260 | + | 1065 | WP_009895015.1 | type VI secretion system protein TssA |
| T6CP001054 | TssB | BTH_RS01340 (tssB) | 317322..317903 | + | 582 | WP_009895017.1 | type VI secretion system contractile sheath small subunit |
| T6CP001055 | TssC | BTH_RS01345 (tssC) | 317896..319404 | + | 1509 | WP_009895019.1 | type VI secretion system contractile sheath large subunit |
| T6CP001056 | TssD | BTH_RS01350 | 319462..319953 | + | 492 | WP_009895021.1 | type VI secretion system tube protein Hcp |
| T6CP001057 | TssE | BTH_RS01355 (tssE) | 319972..320532 | + | 561 | WP_009895023.1 | type VI secretion system baseplate subunit TssE |
| T6CP001058 | TssF | BTH_RS01360 (tssF) | 320537..322408 | + | 1872 | WP_009895028.1 | type VI secretion system baseplate subunit TssF |
| T6CP001059 | TssG | BTH_RS01365 (tssG) | 322372..323688 | + | 1317 | WP_009895030.1 | type VI secretion system baseplate subunit TssG |
| T6CP001060 | TssH | BTH_RS01370 (tssH) | 323701..326358 | + | 2658 | WP_009895032.1 | type VI secretion system ATPase TssH |
| T6CP001061 | TssI | BTH_RS01375 (tssI) | 326355..328559 | + | 2205 | WP_009895034.1 | type VI secretion system tip protein VgrG |
| BTH_RS01380 | 328575..329840 | + | 1266 | WP_009895036.1 | hypothetical protein | ||
| BTH_RS01385 | 329863..334482 | + | 4620 | WP_009895037.1 | RHS domain-containing protein | ||
| BTH_RS29390 | 334730..335177 | - | 448 | pseudogene | transposase | ||
| BTH_RS01400 | 335205..336473 | - | 1269 | WP_011400855.1 | IS256 family transposase | ||
| BTH_RS01405 | 336667..337332 | - | 666 | WP_009895046.1 | HAD-IA family hydrolase | ||
| BTH_RS01415 (nudK) | 337540..338136 | - | 597 | WP_004540486.1 | GDP-mannose pyrophosphatase NudK | ||
| BTH_RS01420 | 338150..338484 | - | 335 | pseudogene | hypothetical protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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