SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP001056
Component protein type	TssD
T6SS ID (Type)	T6SS00112 (Type i3)
Strain	Burkholderia thailandensis E264
Replicon	chromosome II
Sequence	Protein sequence (164 a.a.); Nucleotide sequence (492 bp)
Reference	[1] Russell AB, Singh P, Brittnacher M, et al. A widespread bacterial type VI secretion effector superfamily identified using a heuristic approach. Cell Host Microbe. 2012 May 17;11(5):538-49. doi: 10.1016/j.chom.2012.04.007. PMID: 22607806 [2] Schwarz S, West TE, Boyer F, et al. Burkholderia type VI secretion systems have distinct roles in eukaryotic and bacterial cell interactions. PLoS Pathog. 2010 Aug 26;6(8):e1001068. doi: 10.1371/journal.ppat.1001068. PMID: 20865170

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	BTH_RS01350
Coordinate (Strand)	319462..319953 (+)
NCBI ID	WP_009895021.1
RefSeq	NC_007650
Uniprot ID	-
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
T6SS_HCP	PF05638.14	2.1e-33	6..138

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-163	MGVAMFMKVDGVTGESADAQHKGWTDIQSFSWGASQPGAMASGSGGNAGKASFNDLVVAAYMDKGATAIIKNCANGKHLSSVEISACKTGGSQIEFMRVTLQEVLVTSAQIAGVDPGDAADRLMMQYGFQAAKVKKQYWQQNDNGGKGAEVSVGWNIKENTEM

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9150	-	-

Protein sequence: 164 a.a.

						>T6CP001056 NC_007650:319462-319953 [Burkholderia thailandensis E264] [TssD]
MGVAMFMKVDGVTGESADAQHKGWTDIQSFSWGASQPGAMASGSGGNAGKASFNDLVVAAYMDKGATAIIKNCANGKHLS
SVEISACKTGGSQIEFMRVTLQEVLVTSAQIAGVDPGDAADRLMMQYGFQAAKVKKQYWQQNDNGGKGAEVSVGWNIKEN
TEM*					

Nucleotide sequence: 492 bp

						>T6CP001056 NC_007650:319462-319953 [Burkholderia thailandensis E264] [TssD]
ATGGGCGTGGCAATGTTTATGAAAGTGGACGGCGTCACCGGCGAATCGGCCGACGCGCAGCACAAGGGCTGGACCGACAT
CCAGTCGTTCTCGTGGGGCGCGAGCCAGCCGGGCGCGATGGCGAGCGGCAGCGGCGGCAACGCGGGCAAGGCGAGCTTCA
ACGATCTCGTCGTCGCCGCATACATGGACAAGGGCGCGACGGCGATCATCAAGAACTGCGCGAACGGCAAGCATTTGTCG
TCCGTCGAGATCTCGGCGTGCAAGACGGGCGGCTCGCAGATCGAGTTCATGCGCGTGACGCTGCAGGAAGTGCTCGTCAC
GTCCGCGCAGATCGCGGGCGTCGATCCGGGCGACGCGGCCGACCGGCTGATGATGCAGTACGGCTTCCAGGCCGCGAAGG
TCAAGAAGCAGTACTGGCAGCAGAACGACAACGGCGGCAAGGGCGCCGAGGTGTCGGTCGGCTGGAACATCAAGGAAAAC
ACCGAGATGTGA					