Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00019  |
| T6SS type | Type i2 |
| Strain | Yersinia pestis CO92 |
| Replicon (RefSeq) | chromosome (NC_003143) |
| Location | 1651381..1695174 |
| Function | - |
| Comment | - |
| References | [1] Boyer F et al (2009) Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 0.488888889. [PudMed:19284603] |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | PAAR | TagL | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| YPO_RS08255 | 1647116..1647334 | + | 219 | WP_002213036.1 | hypothetical protein | ||
| YPO_RS08260 | 1647598..1648122 | + | 525 | WP_002213034.1 | beta-hydroxyacyl-ACP dehydratase | ||
| YPO_RS08265 | 1648112..1649395 | + | 1284 | WP_002213032.1 | beta-ketoacyl-[acyl-carrier-protein] synthase family protein | ||
| YPO_RS08270 | 1649397..1650134 | + | 738 | WP_002213030.1 | SDR family oxidoreductase | ||
| YPO_RS08275 | 1650150..1651388 | + | 1239 | WP_002213028.1 | hydroxymethylglutaryl-CoA synthase family protein | ||
| YPO_RS08280 | 1651381..1652100 | + | 720 | WP_002213026.1 | enoyl-CoA hydratase/isomerase family protein | ||
| YPO_RS08285 | 1652102..1652854 | + | 753 | WP_002213025.1 | enoyl-CoA hydratase/isomerase family protein | ||
| YPO_RS08290 | 1652857..1653645 | + | 789 | WP_002213024.1 | SDR family oxidoreductase | ||
| YPO_RS08295 | 1653732..1654172 | + | 441 | WP_002228570.1 | lipocalin-like domain-containing protein | ||
| YPO_RS08300 | 1654210..1654458 | + | 249 | WP_002213017.1 | acyl carrier protein | ||
| YPO_RS08305 | 1654557..1655405 | + | 849 | WP_002213016.1 | ACP S-malonyltransferase | ||
| T6CP000142 | TssB | YPO_RS08310 (tssB) | 1656394..1656894 | + | 501 | WP_002213014.1 | type VI secretion system contractile sheath small subunit |
| T6CP000143 | TssC | YPO_RS08315 (tssC) | 1656937..1658487 | + | 1551 | WP_002214707.1 | type VI secretion system contractile sheath large subunit |
| T6CP000144 | TssK | YPO_RS08320 (tssK) | 1658499..1659851 | + | 1353 | WP_002213011.1 | type VI secretion system baseplate subunit TssK |
| T6CP009289 | TssL | YPO_RS08325 | 1659848..1660534 | + | 687 | WP_002210015.1 | type VI secretion system protein TssL, short form |
| T6CP011408 | TagL | YPO_RS08330 | 1660534..1662270 | + | 1737 | WP_002214568.1 | OmpA family protein |
| T6CP008412 | TssD | YPO_RS08335 | 1662274..1662765 | + | 492 | WP_002210014.1 | Hcp family type VI secretion system effector |
| T6CP000145 | TssH | YPO_RS08340 (tssH) | 1663153..1665795 | + | 2643 | WP_002211927.1 | type VI secretion system ATPase TssH |
| T6CP000146 | TssI | YPO_RS08345 | 1665798..1668146 | + | 2349 | WP_002211928.1 | type VI secretion system tip protein VgrG |
| YPO_RS08350 | 1668162..1670462 | + | 2301 | WP_002211929.1 | M23 family metallopeptidase | ||
| YPO_RS08355 | 1670459..1671232 | + | 774 | WP_002211930.1 | hypothetical protein | ||
| YPO_RS08360 | 1671386..1671646 | + | 261 | WP_002211931.1 | DUF2345 domain-containing protein | ||
| YPO_RS08365 | 1671662..1673845 | + | 2184 | WP_002211932.1 | M23 family metallopeptidase | ||
| YPO_RS08370 | 1674018..1674488 | + | 471 | WP_002214564.1 | hypothetical protein | ||
| YPO_RS08375 | 1674953..1675823 | - | 871 | pseudogene | transposase | ||
| YPO_RS08380 | 1676653..1677885 | + | 1233 | WP_002211935.1 | hypothetical protein | ||
| T6CP000147 | TssM | YPO_RS08385 | 1677882..1681304 | + | 3423 | WP_002211936.1 | type VI secretion system membrane subunit |
| T6CP008413 | TssA | YPO_RS08390 (tssA) | 1681348..1682949 | + | 1602 | WP_002211937.1 | type VI secretion system protein TssA |
| T6CP011407 | PAAR | YPO_RS08395 | 1682967..1684025 | + | 1059 | WP_002211938.1 | PAAR domain-containing protein |
| YPO_RS08400 | 1684040..1684495 | + | 456 | WP_002211939.1 | hypothetical protein | ||
| T6CP000148 | TssF | YPO_RS08405 (tssF) | 1684716..1686479 | + | 1764 | WP_002211940.1 | type VI secretion system baseplate subunit TssF |
| T6CP000149 | TssG | YPO_RS08410 (tssG) | 1686443..1687528 | + | 1086 | WP_002211941.1 | type VI secretion system baseplate subunit TssG |
| T6CP000150 | TssJ | YPO_RS08415 (tssJ) | 1687503..1688084 | + | 582 | WP_002214552.1 | type VI secretion system lipoprotein TssJ |
| T6CP000151 | TssE | YPO_RS08420 (tssE) | 1688084..1688536 | + | 453 | WP_002211943.1 | type VI secretion system baseplate subunit TssE |
| T6CP008414 | TssA | YPO_RS08425 | 1688561..1689928 | + | 1368 | WP_002211944.1 | type VI secretion system ImpA and VasL domain-containing protein |
| YPO_RS08430 | 1690140..1690763 | - | 624 | WP_002211945.1 | hypothetical protein | ||
| YPO_RS08435 | 1691446..1693041 | + | 1596 | WP_002227996.1 | ABC-F family ATPase | ||
| YPO_RS08440 | 1693269..1693922 | + | 654 | WP_002211947.1 | hypothetical protein | ||
| YPO_RS08445 | 1693966..1695174 | - | 1209 | WP_002209743.1 | IS256 family transposase | ||
| YPO_RS08450 (moeB) | 1695310..1696080 | - | 771 | WP_002211948.1 | molybdopterin-synthase adenylyltransferase MoeB | ||
| YPO_RS08455 (moeA) | 1696082..1697356 | - | 1275 | WP_002211949.1 | molybdopterin molybdotransferase MoeA | ||
| YPO_RS08460 (darE) | 1697891..1699201 | - | 1311 | WP_002211950.1 | darobactin maturation radical SAM/SPASM protein DarE | ||
| YPO_RS08465 (darD) | 1699211..1699879 | - | 669 | WP_002211951.1 | darobactin export ABC transporter ATP-binding protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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