SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP011407
Component protein type	PAAR
T6SS ID (Type)	T6SS00019 (Type i2)
Strain	Yersinia pestis CO92
Replicon	chromosome
Sequence	Protein sequence (353 a.a.); Nucleotide sequence (1059 bp)
Reference	[1] Boyer F, Fichant G, Berthod J, et al. Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources? BMC Genomics. 2009 Mar 12;10:104. doi: 10.1186/1471-2164-10-104. PMID: 19284603

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	YPO_RS08395
Coordinate (Strand)	1682967..1684025 (+)
NCBI ID	WP_002211938.1
RefSeq	NC_003143
Uniprot ID	-
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
Ntox44	PF15607.8	2e-30	196..303
PAAR_motif	PF05488.15	8.6e-08	9..53

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-352	MAKGYYLGVGDETTCGGVIIEGDATHVLMGKAVAREQDRVTCGKHPGTYIIIGHVPGDSVNGRKFAGTLNSQSNCPCKAWFIPSLVHDTYEFGARSKSQNMSEISTEVEREMVENVSESEEKSKVVCAHIDGALVVASYILDEIKKNVKSDTADKIRSFIDNDLYKKRLKEWQDSPWYARMNAPPQPEIISASVLWFMAVKSGAKWDHKPKIRDQFKAYAVSRPLVGSGTRSKSYFHKYEEHDYFYDVWSNIHYGYVGLSLGFDESYLLLGSTLEQVRTSIGSKPDPIDDITCMKIGYALYHQHGKYAETLDVRHILDALESASDLDLAISRQIHWCWNNDNSSQIDHPQGK

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9826	-	-

Protein sequence: 353 a.a.

						>T6CP011407 NC_003143:1682967-1684025 [Yersinia pestis CO92] [PAAR]
MAKGYYLGVGDETTCGGVIIEGDATHVLMGKAVAREQDRVTCGKHPGTYIIIGHVPGDSVNGRKFAGTLNSQSNCPCKAW
FIPSLVHDTYEFGARSKSQNMSEISTEVEREMVENVSESEEKSKVVCAHIDGALVVASYILDEIKKNVKSDTADKIRSFI
DNDLYKKRLKEWQDSPWYARMNAPPQPEIISASVLWFMAVKSGAKWDHKPKIRDQFKAYAVSRPLVGSGTRSKSYFHKYE
EHDYFYDVWSNIHYGYVGLSLGFDESYLLLGSTLEQVRTSIGSKPDPIDDITCMKIGYALYHQHGKYAETLDVRHILDAL
ESASDLDLAISRQIHWCWNNDNSSQIDHPQGK*					

Nucleotide sequence: 1059 bp

						>T6CP011407 NC_003143:1682967-1684025 [Yersinia pestis CO92] [PAAR]
ATGGCAAAAGGCTATTACCTTGGGGTTGGGGATGAAACAACCTGCGGCGGCGTGATCATCGAAGGTGACGCCACACATGT
CTTGATGGGTAAAGCGGTGGCCCGTGAACAAGACAGAGTGACCTGCGGTAAACATCCGGGAACCTATATTATTATCGGCC
ATGTTCCTGGCGATTCGGTAAATGGCCGCAAGTTTGCGGGCACCTTGAATAGTCAAAGCAATTGCCCGTGCAAGGCGTGG
TTTATTCCTTCTTTGGTGCATGATACGTATGAGTTTGGTGCAAGAAGTAAATCACAAAATATGTCTGAAATTAGTACTGA
AGTCGAACGTGAGATGGTAGAAAATGTGAGTGAATCAGAAGAAAAATCTAAAGTTGTCTGTGCCCATATTGATGGCGCTT
TAGTAGTAGCGAGTTATATCCTTGATGAAATAAAGAAAAATGTAAAAAGTGATACCGCTGATAAAATCAGATCTTTTATC
GATAATGACCTCTATAAAAAAAGACTTAAGGAGTGGCAGGATTCTCCTTGGTACGCGAGAATGAATGCACCTCCACAGCC
TGAAATAATATCGGCATCGGTTTTATGGTTTATGGCGGTCAAGAGTGGTGCTAAATGGGATCATAAACCTAAAATTAGAG
ATCAATTTAAAGCATATGCAGTTTCTCGTCCTCTGGTCGGAAGCGGAACCCGATCAAAAAGCTATTTTCATAAATATGAA
GAACATGATTATTTTTATGATGTCTGGTCCAATATTCACTATGGTTATGTAGGCTTAAGTCTTGGTTTTGATGAGTCATA
TTTATTACTTGGCTCAACTCTTGAGCAAGTAAGAACCAGCATCGGGAGTAAACCAGATCCTATAGATGATATTACATGTA
TGAAAATTGGCTATGCACTCTATCATCAACATGGAAAATATGCTGAGACGTTAGATGTCAGGCATATACTCGATGCTCTT
GAATCAGCATCGGACCTTGATCTAGCTATTTCAAGACAAATTCATTGGTGTTGGAATAATGATAATTCGAGTCAAATTGA
TCACCCGCAGGGTAAGTAA					