SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP011408
Component protein type	TagL
T6SS ID (Type)	T6SS00019 (Type i2)
Strain	Yersinia pestis CO92
Replicon	chromosome
Sequence	Protein sequence (579 a.a.); Nucleotide sequence (1737 bp)
Reference	[1] Boyer F, Fichant G, Berthod J, et al. Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources? BMC Genomics. 2009 Mar 12;10:104. doi: 10.1186/1471-2164-10-104. PMID: 19284603

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	YPO_RS08330
Coordinate (Strand)	1660534..1662270 (+)
NCBI ID	WP_002214568.1
RefSeq	NC_003143
Uniprot ID	-
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
OmpA	PF00691.22	2.1e-15	447..543

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Inside	1-8	MSRWWQRG
Transmembrane helix	9-31	LWLWAGLLAVILCLAFLPLSPWG
Outside	32-578	RWLMLAWVVLICMLGGSRAGRQAAGASSDPLFAGLATENGLLPENSRLPVVLVCGDGLASWFGRERSHQSAQGCWLRVDDISTLRQFARQLLWQRPEWAAQLAVMMVVNPQQRRDERLLAADLQELRWQLMQLRRDSRHPVPLLLSSTVATSVARDTVWLSQQQTPPLTLWSTVSTPGSLADWQRAESRAVQAERLKQAVLFSSQHDWLNAQVLPVLQAPNADVAPLAPQQIIQQQVASLADPVPASLWQHWLAAHTTLTQVAGWHPPPPAAHDALPLPDFVFSALPLGSGVSSRRRVLRHGVTLLTLAAMVALCSSAWQNRQLLHRVAFDIRQYHSVAMTDYSPKAQAVAVLRRDAGLLDEGYRNGEPLRLGLGLYRGERLRPPLLAAIKSYIPPPPPPPAPPAPKTVRLDSLSLFDVGKFTLNAGSTKMLVTALIDIKAKPGWLIVVAGHTDITGDAQANHILSLKRAEALRDWMLSTSDVSPTCFAVQGYGATRPIADNDTPDGRALNRRVEISLVPQADACQVPDVKTASQDESDVSTQEMEK

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9214	-	-

Protein sequence: 579 a.a.

						>T6CP011408 NC_003143:1660534-1662270 [Yersinia pestis CO92] [TagL]
MSRWWQRGLWLWAGLLAVILCLAFLPLSPWGRWLMLAWVVLICMLGGSRAGRQAAGASSDPLFAGLATENGLLPENSRLP
VVLVCGDGLASWFGRERSHQSAQGCWLRVDDISTLRQFARQLLWQRPEWAAQLAVMMVVNPQQRRDERLLAADLQELRWQ
LMQLRRDSRHPVPLLLSSTVATSVARDTVWLSQQQTPPLTLWSTVSTPGSLADWQRAESRAVQAERLKQAVLFSSQHDWL
NAQVLPVLQAPNADVAPLAPQQIIQQQVASLADPVPASLWQHWLAAHTTLTQVAGWHPPPPAAHDALPLPDFVFSALPLG
SGVSSRRRVLRHGVTLLTLAAMVALCSSAWQNRQLLHRVAFDIRQYHSVAMTDYSPKAQAVAVLRRDAGLLDEGYRNGEP
LRLGLGLYRGERLRPPLLAAIKSYIPPPPPPPAPPAPKTVRLDSLSLFDVGKFTLNAGSTKMLVTALIDIKAKPGWLIVV
AGHTDITGDAQANHILSLKRAEALRDWMLSTSDVSPTCFAVQGYGATRPIADNDTPDGRALNRRVEISLVPQADACQVPD
VKTASQDESDVSTQEMEK*					

Nucleotide sequence: 1737 bp

						>T6CP011408 NC_003143:1660534-1662270 [Yersinia pestis CO92] [TagL]
ATGAGTCGGTGGTGGCAACGTGGGTTGTGGCTCTGGGCGGGTTTGCTGGCGGTCATCTTGTGTCTGGCATTTCTGCCGCT
CTCCCCGTGGGGGCGCTGGCTGATGCTGGCATGGGTGGTGCTGATTTGCATGCTGGGCGGGTCGCGGGCAGGGCGGCAAG
CGGCCGGTGCATCCTCTGATCCGCTGTTCGCCGGGTTGGCAACTGAAAACGGTCTTCTGCCTGAAAACAGTCGCTTACCG
GTGGTGTTGGTATGTGGTGATGGTCTGGCGTCATGGTTTGGTCGCGAACGGTCACACCAGAGTGCACAGGGCTGCTGGCT
GCGGGTGGATGATATCAGCACCCTGCGGCAGTTTGCCCGACAACTGCTGTGGCAACGGCCGGAATGGGCCGCTCAGTTGG
CGGTGATGATGGTCGTGAACCCGCAGCAACGCCGCGATGAGCGCCTGCTGGCCGCCGATCTGCAAGAGCTGCGCTGGCAA
CTGATGCAACTGCGCCGCGATAGCCGCCATCCTGTTCCCTTGCTCCTGAGCAGCACGGTGGCCACCTCGGTTGCCCGTGA
TACGGTCTGGCTGTCACAGCAGCAGACACCGCCGCTGACACTCTGGTCAACCGTCTCGACGCCGGGCTCTCTGGCCGACT
GGCAGCGTGCGGAAAGCCGTGCCGTACAGGCCGAACGACTGAAACAGGCGGTGCTGTTCAGCAGCCAGCATGACTGGCTG
AACGCACAGGTGCTGCCGGTATTGCAGGCACCCAATGCGGATGTTGCCCCCCTTGCCCCGCAACAGATTATTCAACAGCA
GGTTGCCAGTCTGGCCGATCCGGTGCCTGCCTCGCTGTGGCAGCACTGGCTGGCGGCGCATACCACGCTGACACAGGTGG
CGGGTTGGCATCCACCGCCGCCCGCCGCCCATGACGCCTTACCGCTGCCGGATTTTGTCTTTTCAGCGCTTCCTCTTGGT
AGCGGGGTGTCGTCACGCCGTCGGGTACTGCGCCATGGTGTCACCTTACTGACGTTGGCGGCGATGGTGGCGTTGTGCAG
CAGCGCCTGGCAGAACCGGCAACTGTTGCACCGGGTGGCCTTTGATATCCGTCAGTACCACAGCGTGGCGATGACGGATT
ATTCCCCGAAAGCGCAGGCGGTGGCGGTATTACGCCGTGATGCGGGGCTGCTTGATGAAGGGTACCGCAACGGTGAACCG
CTGCGTCTGGGCCTGGGGTTATATCGGGGGGAGCGGCTGCGCCCGCCGCTGTTGGCGGCGATCAAAAGCTACATCCCGCC
CCCTCCGCCCCCTCCCGCGCCACCGGCGCCGAAAACCGTGCGCCTCGACAGCCTGTCACTGTTCGATGTGGGTAAATTCA
CGCTGAATGCGGGGTCCACCAAAATGCTGGTCACGGCGCTGATCGACATCAAAGCCAAACCCGGCTGGCTGATCGTGGTG
GCCGGGCATACCGACATCACCGGCGATGCGCAGGCCAACCACATTCTGTCGCTTAAGCGCGCCGAAGCATTACGCGACTG
GATGCTGTCAACCAGCGACGTCTCGCCGACCTGCTTTGCGGTGCAAGGTTACGGGGCCACACGCCCTATCGCCGACAACG
ATACTCCCGACGGTCGGGCGCTCAACCGCCGGGTCGAAATCAGTCTGGTACCACAGGCTGATGCCTGTCAGGTGCCGGAT
GTAAAAACAGCGTCACAGGATGAAAGTGACGTATCAACGCAAGAAATGGAGAAGTAA					