Detailed information of component protein


Summary

Component ID T6CP000147
Component protein type TssM
T6SS ID (Type) T6SS00019 insolico (Type i2)
Strain Yersinia pestis CO92
Replicon chromosome
Sequence Protein sequence (1141 a.a.); Nucleotide sequence (3423 bp)
Reference
insolico Bioinformatics investigation has been performed on this T6SS
External database links

Locus tag (Gene) YPO_RS08385
Coordinate (Strand) 1677882..1681304 (+)
NCBI ID WP_002211936.1
RefSeq NC_003143
Uniprot ID -
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related PF06761.14 8.2e-63 418..735
IcmF_C PF06744.14 2.4e-22 999..1098
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-12 VKRIALPIKKPE
Transmembrane helix 13-35 VWFWIVALLFLLAGAVLCWLVWQ
Outside 36-49 HPERVGLIPGTPQR
Transmembrane helix 50-72 DRWLTGLVVGTGILTLCALLSYA
Inside 73-369 GTRLSGRKHFDELRQQAQGDDAPLPEDNAQAGETQQGEPSRLKTRLRRRYGLFWRDKVRLLMVVGEPDEIAALAPQLAEQGWLEGQRTVLIHGGSLQRPADETGLSEWRKLRRGRPLDGIVWAMTAAQSGTPQWMDNGLRTLEKMGAALRYQPPVYLWQVCDSDWPQDSRTEQPVGAVFPAKATPEKVEQQLRALLPQLREQGMQQLSIEPHHDFLLRLAQSLDQGDAARWRQRLTPWFTEYAARIPLRGLMFSLPDTSASAAQVHEKSWTVPASWQGVLDDCRGARGRRVGLPWEQ
Transmembrane helix 370-392 TLCYSLLALIVLWGVGSVVSFAV
Outside 393-1140 NRHQMVSAAQQAQQLAQSHAVSDQQLMALQALRNDIGRLQSRVAQGAPWYQRFGLDHNAPLLEVLMPWYGQANNRILRDATAQSLYQKLSELAELPANSPQRAARAKTGYDQLKAYLMMARPEKADAVFYAQVMQTTEPTRAGVSPGLWQSLAPDLWQFYAQNLPAQPDWKITPDTGLISQVRQVLLGQMGQRNAESTLYENMLLSVRRNYADMTLMDMTGDTDAQRLFQTSESVPGMFTRKAWDEQIQQAIDKTVASRREEIDWVLSDNRRAISEDISPEALKKRLTERYFTDFAGSWLSFLNSLHWNEAHNLSDVIDQLTLMSDVRQSPLIALMNTLAWQGQTGQQNQALSDSLVKSAKALMNKDQAPAIDQSAGGPVGPLDETFGPLLALMGKGDAQNRLSSDSSLSLQTLLTRVTRVRLKLQQVVNASDPQEMTQVLAQTVFQGKSVDLTDTQEYGSLIAASLGEEWSSFGQTMFVQPLTQAWETVLQPSSASLNDQWKNAVVANWKSAFDGRYPFAASKSDASLPMLAEFIRKDSGRIDSFLTRELGGVLHKEGTRWVPNKVNSQGLTFNPAFLAAINQLSQISDILFTDGSQGLRFELLARPVPNVVETNLAIDGQKLHYFNQMESWQSFRWPGETYKPGTMLTWTGVSSGARLYGDYQGTWGLIRWLEQAKQKKLDEGRYQLTFTTADKQPLQWILRTELGKGPLGLLQLRNFTLPAQIFLIQHAPLAIADMSDDEDMAED


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9947 - -


  Protein sequence: 1141 a.a.    

>T6CP000147 NC_003143:1677882-1681304 [Yersinia pestis CO92] [TssM]
VKRIALPIKKPEVWFWIVALLFLLAGAVLCWLVWQHPERVGLIPGTPQRDRWLTGLVVGTGILTLCALLSYAGTRLSGRK
HFDELRQQAQGDDAPLPEDNAQAGETQQGEPSRLKTRLRRRYGLFWRDKVRLLMVVGEPDEIAALAPQLAEQGWLEGQRT
VLIHGGSLQRPADETGLSEWRKLRRGRPLDGIVWAMTAAQSGTPQWMDNGLRTLEKMGAALRYQPPVYLWQVCDSDWPQD
SRTEQPVGAVFPAKATPEKVEQQLRALLPQLREQGMQQLSIEPHHDFLLRLAQSLDQGDAARWRQRLTPWFTEYAARIPL
RGLMFSLPDTSASAAQVHEKSWTVPASWQGVLDDCRGARGRRVGLPWEQTLCYSLLALIVLWGVGSVVSFAVNRHQMVSA
AQQAQQLAQSHAVSDQQLMALQALRNDIGRLQSRVAQGAPWYQRFGLDHNAPLLEVLMPWYGQANNRILRDATAQSLYQK
LSELAELPANSPQRAARAKTGYDQLKAYLMMARPEKADAVFYAQVMQTTEPTRAGVSPGLWQSLAPDLWQFYAQNLPAQP
DWKITPDTGLISQVRQVLLGQMGQRNAESTLYENMLLSVRRNYADMTLMDMTGDTDAQRLFQTSESVPGMFTRKAWDEQI
QQAIDKTVASRREEIDWVLSDNRRAISEDISPEALKKRLTERYFTDFAGSWLSFLNSLHWNEAHNLSDVIDQLTLMSDVR
QSPLIALMNTLAWQGQTGQQNQALSDSLVKSAKALMNKDQAPAIDQSAGGPVGPLDETFGPLLALMGKGDAQNRLSSDSS
LSLQTLLTRVTRVRLKLQQVVNASDPQEMTQVLAQTVFQGKSVDLTDTQEYGSLIAASLGEEWSSFGQTMFVQPLTQAWE
TVLQPSSASLNDQWKNAVVANWKSAFDGRYPFAASKSDASLPMLAEFIRKDSGRIDSFLTRELGGVLHKEGTRWVPNKVN
SQGLTFNPAFLAAINQLSQISDILFTDGSQGLRFELLARPVPNVVETNLAIDGQKLHYFNQMESWQSFRWPGETYKPGTM
LTWTGVSSGARLYGDYQGTWGLIRWLEQAKQKKLDEGRYQLTFTTADKQPLQWILRTELGKGPLGLLQLRNFTLPAQIFL
IQHAPLAIADMSDDEDMAED*

  Nucleotide sequence: 3423 bp    

>T6CP000147 NC_003143:1677882-1681304 [Yersinia pestis CO92] [TssM]
GTGAAGCGCATTGCCTTACCGATTAAAAAGCCAGAAGTCTGGTTCTGGATTGTTGCCCTGCTGTTTTTGCTGGCCGGTGC
CGTGTTGTGCTGGCTGGTCTGGCAACACCCCGAACGGGTGGGGTTAATTCCGGGGACACCGCAACGTGACCGTTGGCTGA
CGGGACTGGTGGTGGGAACGGGGATCCTGACCCTGTGCGCATTACTGTCGTATGCGGGGACCCGGTTATCCGGCAGAAAA
CACTTTGATGAGCTACGGCAGCAGGCACAGGGCGATGATGCGCCGTTGCCGGAAGACAACGCGCAGGCGGGTGAGACTCA
GCAGGGTGAACCGTCCCGCCTAAAAACCCGCCTGCGCCGCCGTTACGGTCTGTTCTGGCGCGACAAAGTCCGGCTGCTGA
TGGTGGTGGGTGAACCTGACGAAATCGCCGCGCTGGCCCCGCAACTGGCGGAGCAGGGCTGGCTGGAAGGGCAGCGCACG
GTGTTGATACACGGTGGCAGTTTACAACGTCCGGCGGATGAAACCGGGCTGAGTGAGTGGCGCAAACTGCGCCGTGGCCG
CCCGTTGGATGGCATTGTCTGGGCGATGACCGCCGCGCAGAGTGGCACGCCACAGTGGATGGATAACGGCCTGCGAACGC
TGGAAAAAATGGGTGCCGCCTTGCGCTATCAACCGCCGGTGTATCTGTGGCAGGTCTGTGACAGCGACTGGCCTCAGGAT
TCGCGGACGGAGCAGCCGGTCGGGGCGGTGTTCCCGGCGAAGGCTACGCCAGAAAAGGTGGAGCAGCAACTGCGTGCCCT
GTTGCCTCAGTTACGTGAACAGGGAATGCAGCAGCTTTCCATCGAGCCGCACCATGATTTCTTGTTGCGTCTGGCGCAGT
CACTGGATCAGGGCGATGCGGCTCGCTGGCGGCAGCGTCTGACGCCGTGGTTTACCGAGTATGCCGCGCGTATTCCCTTG
CGTGGGCTGATGTTCAGTTTACCCGATACCTCTGCATCGGCGGCGCAGGTACATGAGAAAAGCTGGACGGTACCGGCCAG
TTGGCAGGGGGTACTGGATGATTGCCGGGGGGCGCGTGGACGCCGTGTCGGGCTGCCGTGGGAGCAGACACTGTGCTACA
GCTTGCTGGCACTGATTGTCTTGTGGGGTGTGGGCAGCGTGGTGTCATTTGCGGTCAACCGCCACCAGATGGTCTCTGCC
GCACAACAAGCACAGCAACTGGCGCAGTCGCACGCGGTCTCCGACCAGCAACTGATGGCCCTACAAGCCCTGCGAAATGA
TATCGGGCGCTTACAATCTCGCGTGGCGCAGGGCGCGCCGTGGTATCAGCGCTTTGGTCTGGACCATAATGCGCCGCTGC
TTGAGGTCCTGATGCCGTGGTATGGTCAGGCCAACAACCGTATTCTCAGGGATGCCACCGCGCAGAGCCTGTATCAGAAA
CTCAGCGAACTGGCGGAGCTGCCCGCCAACAGCCCGCAACGGGCAGCACGGGCAAAAACAGGCTATGACCAGTTAAAGGC
TTATCTGATGATGGCCCGCCCGGAAAAAGCCGATGCTGTATTTTATGCTCAGGTGATGCAGACCACCGAGCCTACACGGG
CCGGTGTCTCCCCCGGTCTGTGGCAGAGTCTGGCGCCCGACTTGTGGCAGTTTTATGCACAAAATCTGCCCGCTCAGCCG
GACTGGAAAATTACCCCGGATACCGGGTTGATCAGCCAGGTGCGGCAGGTGTTGCTGGGGCAGATGGGTCAGCGCAATGC
AGAAAGTACGCTGTATGAAAACATGCTGCTGTCGGTGCGCCGCAACTATGCCGACATGACGCTGATGGACATGACCGGCG
ATACCGATGCTCAGCGTCTGTTTCAGACCTCGGAATCCGTGCCCGGTATGTTCACCCGCAAGGCCTGGGATGAGCAAATC
CAGCAGGCGATAGATAAAACGGTGGCCTCCCGCCGCGAAGAAATTGACTGGGTATTGAGTGATAACCGCCGGGCGATATC
CGAAGATATCTCACCGGAAGCGCTGAAAAAACGCCTGACCGAACGTTATTTCACCGATTTTGCTGGCAGTTGGCTGAGTT
TCCTCAACAGTTTGCACTGGAATGAGGCGCATAACCTGTCGGATGTGATTGACCAACTGACCTTGATGAGTGATGTACGC
CAGTCGCCGCTGATTGCGCTAATGAACACGCTGGCGTGGCAAGGGCAGACCGGGCAGCAGAATCAGGCATTATCGGATTC
GCTGGTGAAGTCTGCCAAGGCGCTGATGAATAAAGACCAGGCTCCGGCGATTGACCAGAGTGCCGGTGGGCCAGTAGGGC
CACTGGACGAGACCTTTGGCCCGTTGCTGGCACTGATGGGCAAAGGCGATGCACAAAACAGGCTGTCGTCGGACAGCTCG
CTGAGCCTGCAAACGTTGCTCACCCGCGTGACCCGGGTGCGGCTTAAACTCCAGCAGGTGGTCAATGCTTCGGATCCGCA
GGAGATGACACAGGTGCTGGCCCAGACCGTTTTCCAGGGCAAAAGTGTTGATCTGACGGACACGCAGGAGTACGGCAGCC
TGATAGCCGCCAGTCTGGGAGAGGAGTGGAGCAGCTTCGGGCAGACGATGTTTGTTCAGCCGCTGACGCAGGCGTGGGAA
ACCGTGCTGCAACCTTCATCGGCCAGTCTCAACGACCAGTGGAAAAACGCGGTGGTGGCCAACTGGAAATCGGCCTTTGA
TGGCCGCTATCCGTTTGCCGCCAGTAAAAGTGATGCTTCATTGCCGATGCTGGCCGAGTTTATCCGCAAGGACAGCGGGC
GCATCGACAGCTTCCTGACCCGTGAACTGGGCGGCGTGCTGCACAAAGAAGGAACGCGCTGGGTGCCGAATAAGGTGAAC
AGCCAGGGGCTGACCTTTAACCCGGCCTTCCTGGCGGCGATTAATCAACTGAGCCAAATCTCCGACATCTTGTTCACTGA
CGGCAGTCAGGGGCTACGCTTTGAGCTGCTGGCCCGTCCGGTGCCGAATGTGGTGGAAACGAATCTGGCGATTGACGGAC
AGAAATTGCATTATTTCAACCAGATGGAGAGCTGGCAGAGTTTCCGCTGGCCGGGGGAGACCTATAAACCCGGCACGATG
TTGACCTGGACTGGTGTGAGTTCAGGCGCCCGGTTGTACGGTGATTATCAGGGGACATGGGGGCTGATCCGTTGGCTGGA
GCAGGCAAAACAGAAAAAGCTGGATGAAGGGCGCTATCAACTGACCTTCACCACCGCAGATAAACAGCCATTGCAATGGA
TATTACGCACCGAGCTGGGCAAAGGCCCGTTAGGCCTGTTGCAACTGCGTAATTTCACTCTGCCTGCGCAAATTTTTCTG
ATACAGCACGCGCCGCTTGCGATTGCTGACATGTCAGACGATGAAGACATGGCAGAAGACTGA