Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   R8611_RS09590 Genome accession   NZ_AP026927
Coordinates   1868451..1868777 (-) Length   108 a.a.
NCBI ID   WP_317647938.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700178     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1863451..1873777
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8611_RS09545 (PC0174_18600) rnpA 1863468..1863839 (-) 372 WP_000739246.1 ribonuclease P protein component -
  R8611_RS09550 - 1863856..1863987 (-) 132 WP_000768904.1 hypothetical protein -
  R8611_RS09555 (PC0174_18610) - 1863988..1865178 (-) 1191 WP_317647937.1 acetate kinase -
  R8611_RS09560 (PC0174_18620) comYH 1865229..1866182 (-) 954 WP_050199846.1 class I SAM-dependent methyltransferase Machinery gene
  R8611_RS09565 - 1866243..1866837 (-) 595 Protein_1865 class I SAM-dependent methyltransferase -
  R8611_RS09570 (PC0174_18650) comGG/cglG 1866974..1867387 (-) 414 WP_000265631.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8611_RS09575 (PC0174_18660) comGF/cglF 1867365..1867826 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8611_RS09580 (PC0174_18670) comGE/cglE 1867789..1868091 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8611_RS09585 (PC0174_18680) comGD/cglD 1868054..1868458 (-) 405 WP_050199843.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8611_RS09590 (PC0174_18690) comGC/cglC 1868451..1868777 (-) 327 WP_317647938.1 comG operon protein ComGC Machinery gene
  R8611_RS09595 (PC0174_18700) comGB/cglB 1868779..1869795 (-) 1017 WP_317648071.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8611_RS09600 (PC0174_18710) comGA/cglA/cilD 1869743..1870684 (-) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  R8611_RS09605 (PC0174_18720) - 1870760..1871125 (-) 366 WP_000286415.1 DUF1033 family protein -
  R8611_RS09610 (PC0174_18730) - 1871276..1872334 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  R8611_RS09615 (PC0174_18740) nagA 1872497..1873648 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12154.30 Da        Isoelectric Point: 10.1001

>NTDB_id=98540 R8611_RS09590 WP_317647938.1 1868451..1868777(-) (comGC/cglC) [Streptococcus pneumoniae strain PZ900700178]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKD
DGRITEEQVKAYKEHNDKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=98540 R8611_RS09590 WP_317647938.1 1868451..1868777(-) (comGC/cglC) [Streptococcus pneumoniae strain PZ900700178]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAC
GATGGGCGAATCACGGAAGAACAGGTTAAAGCTTATAAAGAACACAATGATAAAAATGGAGGAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae TIGR4

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae Rx1

94.444

100

0.944
  comGC/cglC Streptococcus pneumoniae D39

94.444

100

0.944
  comGC/cglC Streptococcus pneumoniae R6

94.444

100

0.944
  comGC/cglC Streptococcus mitis SK321

91.667

100

0.917
  comGC/cglC Streptococcus mitis NCTC 12261

90.909

91.667

0.833
  comYC Streptococcus gordonii str. Challis substr. CH1

66.019

95.37

0.63
  comYC Streptococcus mutans UA159

60.784

94.444

0.574
  comYC Streptococcus mutans UA140

60.784

94.444

0.574
  comGC Lactococcus lactis subsp. cremoris KW2

54.902

94.444

0.519
  comYC Streptococcus suis isolate S10

66.667

75

0.5
  comGC Staphylococcus aureus MW2

48.837

79.63

0.389
  comGC Staphylococcus aureus N315

48.837

79.63

0.389
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361

Multiple sequence alignment