Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   R8611_RS09595 Genome accession   NZ_AP026927
Coordinates   1868779..1869795 (-) Length   338 a.a.
NCBI ID   WP_317648071.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700178     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1863779..1874795
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8611_RS09550 - 1863856..1863987 (-) 132 WP_000768904.1 hypothetical protein -
  R8611_RS09555 (PC0174_18610) - 1863988..1865178 (-) 1191 WP_317647937.1 acetate kinase -
  R8611_RS09560 (PC0174_18620) comYH 1865229..1866182 (-) 954 WP_050199846.1 class I SAM-dependent methyltransferase Machinery gene
  R8611_RS09565 - 1866243..1866837 (-) 595 Protein_1865 class I SAM-dependent methyltransferase -
  R8611_RS09570 (PC0174_18650) comGG/cglG 1866974..1867387 (-) 414 WP_000265631.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8611_RS09575 (PC0174_18660) comGF/cglF 1867365..1867826 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8611_RS09580 (PC0174_18670) comGE/cglE 1867789..1868091 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8611_RS09585 (PC0174_18680) comGD/cglD 1868054..1868458 (-) 405 WP_050199843.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8611_RS09590 (PC0174_18690) comGC/cglC 1868451..1868777 (-) 327 WP_317647938.1 comG operon protein ComGC Machinery gene
  R8611_RS09595 (PC0174_18700) comGB/cglB 1868779..1869795 (-) 1017 WP_317648071.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8611_RS09600 (PC0174_18710) comGA/cglA/cilD 1869743..1870684 (-) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  R8611_RS09605 (PC0174_18720) - 1870760..1871125 (-) 366 WP_000286415.1 DUF1033 family protein -
  R8611_RS09610 (PC0174_18730) - 1871276..1872334 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  R8611_RS09615 (PC0174_18740) nagA 1872497..1873648 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38520.59 Da        Isoelectric Point: 9.6073

>NTDB_id=98541 R8611_RS09595 WP_317648071.1 1868779..1869795(-) (comGB/cglB) [Streptococcus pneumoniae strain PZ900700178]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVIQMRAGLSQGKSFSEMMESLGFSSTI
ITQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLVFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=98541 R8611_RS09595 WP_317648071.1 1868779..1869795(-) (comGB/cglB) [Streptococcus pneumoniae strain PZ900700178]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGATCCAGATGCGTGCGGGCTTGTCTCAAGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATTTTCAAGCACCATT
ATCACTCAGTTATCCCTAGCTGAAGTTCATGGAAATCTCCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGACAATCT
GGCTAAGGTCAAGAAAAAATTGATTGAAGTAGCGACCTATCCTTTGATTTTGCTGGTTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCAAATTATCGGTAATCTGCCCCAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCTGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

97.929

100

0.979
  comGB/cglB Streptococcus pneumoniae D39

97.929

100

0.979
  comGB/cglB Streptococcus pneumoniae R6

97.929

100

0.979
  comGB/cglB Streptococcus pneumoniae TIGR4

97.929

100

0.979
  comGB/cglB Streptococcus mitis SK321

94.675

100

0.947
  comGB/cglB Streptococcus mitis NCTC 12261

94.379

100

0.944
  comYB Streptococcus gordonii str. Challis substr. CH1

70.833

99.408

0.704
  comYB Streptococcus mutans UA140

57.862

94.083

0.544
  comYB Streptococcus mutans UA159

57.862

94.083

0.544
  comGB Lactococcus lactis subsp. cremoris KW2

51.198

98.817

0.506

Multiple sequence alignment