Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   R8611_RS09580 Genome accession   NZ_AP026927
Coordinates   1867789..1868091 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700178     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1862789..1873091
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8611_RS09545 (PC0174_18600) rnpA 1863468..1863839 (-) 372 WP_000739246.1 ribonuclease P protein component -
  R8611_RS09550 - 1863856..1863987 (-) 132 WP_000768904.1 hypothetical protein -
  R8611_RS09555 (PC0174_18610) - 1863988..1865178 (-) 1191 WP_317647937.1 acetate kinase -
  R8611_RS09560 (PC0174_18620) comYH 1865229..1866182 (-) 954 WP_050199846.1 class I SAM-dependent methyltransferase Machinery gene
  R8611_RS09565 - 1866243..1866837 (-) 595 Protein_1865 class I SAM-dependent methyltransferase -
  R8611_RS09570 (PC0174_18650) comGG/cglG 1866974..1867387 (-) 414 WP_000265631.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8611_RS09575 (PC0174_18660) comGF/cglF 1867365..1867826 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8611_RS09580 (PC0174_18670) comGE/cglE 1867789..1868091 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8611_RS09585 (PC0174_18680) comGD/cglD 1868054..1868458 (-) 405 WP_050199843.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8611_RS09590 (PC0174_18690) comGC/cglC 1868451..1868777 (-) 327 WP_317647938.1 comG operon protein ComGC Machinery gene
  R8611_RS09595 (PC0174_18700) comGB/cglB 1868779..1869795 (-) 1017 WP_317648071.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8611_RS09600 (PC0174_18710) comGA/cglA/cilD 1869743..1870684 (-) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  R8611_RS09605 (PC0174_18720) - 1870760..1871125 (-) 366 WP_000286415.1 DUF1033 family protein -
  R8611_RS09610 (PC0174_18730) - 1871276..1872334 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=98538 R8611_RS09580 WP_000413382.1 1867789..1868091(-) (comGE/cglE) [Streptococcus pneumoniae strain PZ900700178]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=98538 R8611_RS09580 WP_000413382.1 1867789..1868091(-) (comGE/cglE) [Streptococcus pneumoniae strain PZ900700178]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment