Detailed information NTG0098537

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: R8611_RS09575
• Genome accession: NZ_AP026927
• Coordinates: 1867365..1867826 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250531.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700178
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1862365..1872826

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8611_RS09540 (PC0174_18590)	-	1862669..1863493 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
R8611_RS09545 (PC0174_18600)	rnpA	1863468..1863839 (-)	372	WP_000739246.1	ribonuclease P protein component	-
R8611_RS09550	-	1863856..1863987 (-)	132	WP_000768904.1	hypothetical protein	-
R8611_RS09555 (PC0174_18610)	-	1863988..1865178 (-)	1191	WP_317647937.1	acetate kinase	-
R8611_RS09560 (PC0174_18620)	comYH	1865229..1866182 (-)	954	WP_050199846.1	class I SAM-dependent methyltransferase	Machinery gene
R8611_RS09565	-	1866243..1866837 (-)	595	Protein_1865	class I SAM-dependent methyltransferase	-
R8611_RS09570 (PC0174_18650)	comGG/cglG	1866974..1867387 (-)	414	WP_000265631.1	competence type IV pilus minor pilin ComGG	Machinery gene
R8611_RS09575 (PC0174_18660)	comGF/cglF	1867365..1867826 (-)	462	WP_000250531.1	competence type IV pilus minor pilin ComGF	Machinery gene
R8611_RS09580 (PC0174_18670)	comGE/cglE	1867789..1868091 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R8611_RS09585 (PC0174_18680)	comGD/cglD	1868054..1868458 (-)	405	WP_050199843.1	competence type IV pilus minor pilin ComGD	Machinery gene
R8611_RS09590 (PC0174_18690)	comGC/cglC	1868451..1868777 (-)	327	WP_317647938.1	comG operon protein ComGC	Machinery gene
R8611_RS09595 (PC0174_18700)	comGB/cglB	1868779..1869795 (-)	1017	WP_317648071.1	competence type IV pilus assembly protein ComGB	Machinery gene
R8611_RS09600 (PC0174_18710)	comGA/cglA/cilD	1869743..1870684 (-)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
R8611_RS09605 (PC0174_18720)	-	1870760..1871125 (-)	366	WP_000286415.1	DUF1033 family protein	-
R8611_RS09610 (PC0174_18730)	-	1871276..1872334 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17849.37 Da
• Isoelectric Point: 6.4832

>NTDB_id=98537 R8611_RS09575 WP_000250531.1 1867365..1867826(-) (comGF/cglF) [Streptococcus pneumoniae strain PZ900700178]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=98537 R8611_RS09575 WP_000250531.1 1867365..1867826(-) (comGF/cglF) [Streptococcus pneumoniae strain PZ900700178]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae D39	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae R6	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae TIGR4	95.425	100	0.954
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915