Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   R8775_RS09725 Genome accession   NZ_AP026915
Coordinates   1853264..1853590 (-) Length   108 a.a.
NCBI ID   WP_000738630.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700005     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1848264..1858590
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8775_RS09680 (PC0005_18790) rnpA 1848281..1848652 (-) 372 WP_000739246.1 ribonuclease P protein component -
  R8775_RS09685 - 1848669..1848800 (-) 132 WP_000768904.1 hypothetical protein -
  R8775_RS09690 (PC0005_18800) - 1848801..1849991 (-) 1191 WP_050233485.1 acetate kinase -
  R8775_RS09695 (PC0005_18810) comYH 1850042..1850995 (-) 954 WP_050233486.1 class I SAM-dependent methyltransferase Machinery gene
  R8775_RS09700 - 1851056..1851650 (-) 595 Protein_1889 class I SAM-dependent methyltransferase -
  R8775_RS09705 (PC0005_18840) comGG/cglG 1851787..1852200 (-) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8775_RS09710 comGF/cglF 1852178..1852639 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8775_RS09715 (PC0005_18860) comGE/cglE 1852602..1852904 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8775_RS09720 (PC0005_18870) comGD/cglD 1852867..1853271 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8775_RS09725 (PC0005_18880) comGC/cglC 1853264..1853590 (-) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  R8775_RS09730 (PC0005_18890) comGB/cglB 1853592..1854608 (-) 1017 WP_078134945.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8775_RS09735 (PC0005_18900) comGA/cglA/cilD 1854556..1855497 (-) 942 WP_000249569.1 competence type IV pilus ATPase ComGA Machinery gene
  R8775_RS09740 (PC0005_18910) - 1855573..1855938 (-) 366 WP_000286415.1 DUF1033 family protein -
  R8775_RS09745 (PC0005_18920) - 1856089..1857147 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  R8775_RS09750 (PC0005_18930) nagA 1857310..1858461 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12247.38 Da        Isoelectric Point: 9.8692

>NTDB_id=97599 R8775_RS09725 WP_000738630.1 1853264..1853590(-) (comGC/cglC) [Streptococcus pneumoniae strain PZ900700005]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKD
DGRITEEQAKAYKEYHDKNGEANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=97599 R8775_RS09725 WP_000738630.1 1853264..1853590(-) (comGC/cglC) [Streptococcus pneumoniae strain PZ900700005]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAC
GATGGGCGAATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGAAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae D39

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae R6

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae TIGR4

95.37

100

0.954
  comGC/cglC Streptococcus mitis SK321

92.593

100

0.926
  comGC/cglC Streptococcus mitis NCTC 12261

94.898

90.741

0.861
  comYC Streptococcus gordonii str. Challis substr. CH1

67.961

95.37

0.648
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comGC Lactococcus lactis subsp. cremoris KW2

54.902

94.444

0.519
  comYC Streptococcus suis isolate S10

67.901

75

0.509
  comGC Staphylococcus aureus MW2

46.078

94.444

0.435
  comGC Staphylococcus aureus N315

46.078

94.444

0.435
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361

Multiple sequence alignment