Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   R8775_RS09715 Genome accession   NZ_AP026915
Coordinates   1852602..1852904 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700005     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1847602..1857904
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8775_RS09680 (PC0005_18790) rnpA 1848281..1848652 (-) 372 WP_000739246.1 ribonuclease P protein component -
  R8775_RS09685 - 1848669..1848800 (-) 132 WP_000768904.1 hypothetical protein -
  R8775_RS09690 (PC0005_18800) - 1848801..1849991 (-) 1191 WP_050233485.1 acetate kinase -
  R8775_RS09695 (PC0005_18810) comYH 1850042..1850995 (-) 954 WP_050233486.1 class I SAM-dependent methyltransferase Machinery gene
  R8775_RS09700 - 1851056..1851650 (-) 595 Protein_1889 class I SAM-dependent methyltransferase -
  R8775_RS09705 (PC0005_18840) comGG/cglG 1851787..1852200 (-) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8775_RS09710 comGF/cglF 1852178..1852639 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8775_RS09715 (PC0005_18860) comGE/cglE 1852602..1852904 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8775_RS09720 (PC0005_18870) comGD/cglD 1852867..1853271 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8775_RS09725 (PC0005_18880) comGC/cglC 1853264..1853590 (-) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  R8775_RS09730 (PC0005_18890) comGB/cglB 1853592..1854608 (-) 1017 WP_078134945.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8775_RS09735 (PC0005_18900) comGA/cglA/cilD 1854556..1855497 (-) 942 WP_000249569.1 competence type IV pilus ATPase ComGA Machinery gene
  R8775_RS09740 (PC0005_18910) - 1855573..1855938 (-) 366 WP_000286415.1 DUF1033 family protein -
  R8775_RS09745 (PC0005_18920) - 1856089..1857147 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=97597 R8775_RS09715 WP_000413382.1 1852602..1852904(-) (comGE/cglE) [Streptococcus pneumoniae strain PZ900700005]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=97597 R8775_RS09715 WP_000413382.1 1852602..1852904(-) (comGE/cglE) [Streptococcus pneumoniae strain PZ900700005]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment