Detailed information NTG0097596

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: R8775_RS09710
• Genome accession: NZ_AP026915
• Coordinates: 1852178..1852639 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250540.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700005
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1847178..1857639

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8775_RS09675 (PC0005_18780)	-	1847482..1848306 (-)	825	WP_201417385.1	membrane protein insertase YidC	-
R8775_RS09680 (PC0005_18790)	rnpA	1848281..1848652 (-)	372	WP_000739246.1	ribonuclease P protein component	-
R8775_RS09685	-	1848669..1848800 (-)	132	WP_000768904.1	hypothetical protein	-
R8775_RS09690 (PC0005_18800)	-	1848801..1849991 (-)	1191	WP_050233485.1	acetate kinase	-
R8775_RS09695 (PC0005_18810)	comYH	1850042..1850995 (-)	954	WP_050233486.1	class I SAM-dependent methyltransferase	Machinery gene
R8775_RS09700	-	1851056..1851650 (-)	595	Protein_1889	class I SAM-dependent methyltransferase	-
R8775_RS09705 (PC0005_18840)	comGG/cglG	1851787..1852200 (-)	414	WP_000265620.1	competence type IV pilus minor pilin ComGG	Machinery gene
R8775_RS09710	comGF/cglF	1852178..1852639 (-)	462	WP_000250540.1	competence type IV pilus minor pilin ComGF	Machinery gene
R8775_RS09715 (PC0005_18860)	comGE/cglE	1852602..1852904 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R8775_RS09720 (PC0005_18870)	comGD/cglD	1852867..1853271 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
R8775_RS09725 (PC0005_18880)	comGC/cglC	1853264..1853590 (-)	327	WP_000738630.1	comG operon protein ComGC	Machinery gene
R8775_RS09730 (PC0005_18890)	comGB/cglB	1853592..1854608 (-)	1017	WP_078134945.1	competence type IV pilus assembly protein ComGB	Machinery gene
R8775_RS09735 (PC0005_18900)	comGA/cglA/cilD	1854556..1855497 (-)	942	WP_000249569.1	competence type IV pilus ATPase ComGA	Machinery gene
R8775_RS09740 (PC0005_18910)	-	1855573..1855938 (-)	366	WP_000286415.1	DUF1033 family protein	-
R8775_RS09745 (PC0005_18920)	-	1856089..1857147 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17850.40 Da
• Isoelectric Point: 8.0016

>NTDB_id=97596 R8775_RS09710 WP_000250540.1 1852178..1852639(-) (comGF/cglF) [Streptococcus pneumoniae strain PZ900700005]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=97596 R8775_RS09710 WP_000250540.1 1852178..1852639(-) (comGF/cglF) [Streptococcus pneumoniae strain PZ900700005]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae D39	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae R6	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae TIGR4	94.771	100	0.948
comGF/cglF	Streptococcus mitis SK321	93.464	100	0.935
comGF/cglF	Streptococcus mitis NCTC 12261	92.157	100	0.922