Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   R8775_RS09735 Genome accession   NZ_AP026915
Coordinates   1854556..1855497 (-) Length   313 a.a.
NCBI ID   WP_000249569.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700005     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1849556..1860497
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8775_RS09695 (PC0005_18810) comYH 1850042..1850995 (-) 954 WP_050233486.1 class I SAM-dependent methyltransferase Machinery gene
  R8775_RS09700 - 1851056..1851650 (-) 595 Protein_1889 class I SAM-dependent methyltransferase -
  R8775_RS09705 (PC0005_18840) comGG/cglG 1851787..1852200 (-) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8775_RS09710 comGF/cglF 1852178..1852639 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8775_RS09715 (PC0005_18860) comGE/cglE 1852602..1852904 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8775_RS09720 (PC0005_18870) comGD/cglD 1852867..1853271 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8775_RS09725 (PC0005_18880) comGC/cglC 1853264..1853590 (-) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  R8775_RS09730 (PC0005_18890) comGB/cglB 1853592..1854608 (-) 1017 WP_078134945.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8775_RS09735 (PC0005_18900) comGA/cglA/cilD 1854556..1855497 (-) 942 WP_000249569.1 competence type IV pilus ATPase ComGA Machinery gene
  R8775_RS09740 (PC0005_18910) - 1855573..1855938 (-) 366 WP_000286415.1 DUF1033 family protein -
  R8775_RS09745 (PC0005_18920) - 1856089..1857147 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  R8775_RS09750 (PC0005_18930) nagA 1857310..1858461 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  R8775_RS09755 (PC0005_18940) - 1858614..1860431 (-) 1818 WP_001220920.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35660.62 Da        Isoelectric Point: 6.1842

>NTDB_id=97601 R8775_RS09735 WP_000249569.1 1854556..1855497(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain PZ900700005]
MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKMASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDRETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFANRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=97601 R8775_RS09735 WP_000249569.1 1854556..1855497(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain PZ900700005]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCAGCTCGGAAAAAAGGGACGCAGGATATTTATTTTGTCCCTAAGTT
AGACGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATGGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACTTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGCCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGAGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAACAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

98.722

100

0.987
  comGA/cglA/cilD Streptococcus pneumoniae D39

98.722

100

0.987
  comGA/cglA/cilD Streptococcus pneumoniae R6

98.722

100

0.987
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

98.722

100

0.987
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

96.486

100

0.965
  comYA Streptococcus gordonii str. Challis substr. CH1

77.419

99.042

0.767
  comYA Streptococcus mutans UA159

65.916

99.361

0.655
  comYA Streptococcus mutans UA140

65.916

99.361

0.655
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.903

99.042

0.623
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

99.681

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

42.642

84.665

0.361

Multiple sequence alignment