Detailed information NTG0895514

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: R4699_RS10225
• Genome accession: NZ_CP137105
• Coordinates: 2035344..2035667 (+)
• Length: 107 a.a.
• NCBI ID: WP_000738628.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 16H2092
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2030344..2040667

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4699_RS10200	nagA	2030473..2031624 (+)	1152	WP_001134457.1	N-acetylglucosamine-6-phosphate deacetylase	-
R4699_RS10205	-	2031787..2032845 (+)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-
R4699_RS10210	-	2032996..2033361 (+)	366	WP_000286415.1	DUF1033 family protein	-
R4699_RS10215	comGA/cglA/cilD	2033437..2034378 (+)	942	WP_050104907.1	competence type IV pilus ATPase ComGA	Machinery gene
R4699_RS10220	comGB/cglB	2034326..2035342 (+)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
R4699_RS10225	comGC/cglC	2035344..2035667 (+)	324	WP_000738628.1	comG operon protein ComGC	Machinery gene
R4699_RS10230	comGD/cglD	2035630..2036064 (+)	435	WP_000608686.1	competence type IV pilus minor pilin ComGD	Machinery gene
R4699_RS10235	comGE/cglE	2036027..2036329 (+)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R4699_RS10240	comGF/cglF	2036292..2036753 (+)	462	WP_000250520.1	competence type IV pilus minor pilin ComGF	Machinery gene
R4699_RS10245	comGG/cglG	2036731..2037144 (+)	414	WP_000265615.1	competence type IV pilus minor pilin ComGG	Machinery gene
R4699_RS10250	-	2037281..2037868 (+)	588	WP_000679776.1	class I SAM-dependent methyltransferase	-
R4699_RS10255	comYH	2037929..2038882 (+)	954	WP_044813830.1	class I SAM-dependent methyltransferase	Machinery gene
R4699_RS10260	-	2038933..2040123 (+)	1191	WP_050085692.1	acetate kinase	-
R4699_RS10265	-	2040124..2040255 (+)	132	WP_000768904.1	hypothetical protein	-
R4699_RS10270	rnpA	2040272..2040643 (+)	372	WP_000739246.1	ribonuclease P protein component	-

Sequence

Protein

• Length: 107 a.a.
• Molecular weight: 12232.41 Da
• Isoelectric Point: 9.8887

>NTDB_id=895514 R4699_RS10225 WP_000738628.1 2035344..2035667(+) (comGC/cglC) [Streptococcus pneumoniae strain 16H2092]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQD
DGRITEEQAKAYKEYHDKQNTSQIVKD

Nucleotide

• Length: 324 bp

>NTDB_id=895514 R4699_RS10225 WP_000738628.1 2035344..2035667(+) (comGC/cglC) [Streptococcus pneumoniae strain 16H2092]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGAC
GATGGACGCATCACGGAAGAACAGGCTAAAGCCTATAAAGAATACCATGATAAACAAAATACTAGTCAAATCGTTAAAGA
TTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis NCTC 12261	93.458	100	0.935
comGC/cglC	Streptococcus pneumoniae D39	94.175	96.262	0.907
comGC/cglC	Streptococcus pneumoniae R6	94.175	96.262	0.907
comGC/cglC	Streptococcus pneumoniae Rx1	94.175	96.262	0.907
comGC/cglC	Streptococcus pneumoniae TIGR4	93.204	96.262	0.897
comGC/cglC	Streptococcus mitis SK321	88.35	96.262	0.85
comYC	Streptococcus gordonii str. Challis substr. CH1	69.388	91.589	0.636
comYC	Streptococcus mutans UA140	64.211	88.785	0.57
comYC	Streptococcus mutans UA159	64.211	88.785	0.57
comYC	Streptococcus suis isolate S10	69.136	75.701	0.523
comGC	Lactococcus lactis subsp. cremoris KW2	54.639	90.654	0.495
comGC	Staphylococcus aureus MW2	48.837	80.374	0.393
comGC	Staphylococcus aureus N315	48.837	80.374	0.393
comGC	Latilactobacillus sakei subsp. sakei 23K	45.349	80.374	0.364