Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   R4699_RS10235 Genome accession   NZ_CP137105
Coordinates   2036027..2036329 (+) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2092     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2031027..2041329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4699_RS10205 - 2031787..2032845 (+) 1059 WP_000649471.1 zinc-dependent alcohol dehydrogenase family protein -
  R4699_RS10210 - 2032996..2033361 (+) 366 WP_000286415.1 DUF1033 family protein -
  R4699_RS10215 comGA/cglA/cilD 2033437..2034378 (+) 942 WP_050104907.1 competence type IV pilus ATPase ComGA Machinery gene
  R4699_RS10220 comGB/cglB 2034326..2035342 (+) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  R4699_RS10225 comGC/cglC 2035344..2035667 (+) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  R4699_RS10230 comGD/cglD 2035630..2036064 (+) 435 WP_000608686.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4699_RS10235 comGE/cglE 2036027..2036329 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4699_RS10240 comGF/cglF 2036292..2036753 (+) 462 WP_000250520.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4699_RS10245 comGG/cglG 2036731..2037144 (+) 414 WP_000265615.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4699_RS10250 - 2037281..2037868 (+) 588 WP_000679776.1 class I SAM-dependent methyltransferase -
  R4699_RS10255 comYH 2037929..2038882 (+) 954 WP_044813830.1 class I SAM-dependent methyltransferase Machinery gene
  R4699_RS10260 - 2038933..2040123 (+) 1191 WP_050085692.1 acetate kinase -
  R4699_RS10265 - 2040124..2040255 (+) 132 WP_000768904.1 hypothetical protein -
  R4699_RS10270 rnpA 2040272..2040643 (+) 372 WP_000739246.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=895516 R4699_RS10235 WP_000413382.1 2036027..2036329(+) (comGE/cglE) [Streptococcus pneumoniae strain 16H2092]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=895516 R4699_RS10235 WP_000413382.1 2036027..2036329(+) (comGE/cglE) [Streptococcus pneumoniae strain 16H2092]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4