Detailed information NTG0895518

Bioinformatically predicted

Overview

• Name: comGG/cglG
• Type: Machinery gene
• Locus tag: R4699_RS10245
• Genome accession: NZ_CP137105
• Coordinates: 2036731..2037144 (+)
• Length: 137 a.a.
• NCBI ID: WP_000265615.1
• Uniprot ID: C1CA94
• Organism: Streptococcus pneumoniae strain 16H2092
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2031731..2042144

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4699_RS10205	-	2031787..2032845 (+)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-
R4699_RS10210	-	2032996..2033361 (+)	366	WP_000286415.1	DUF1033 family protein	-
R4699_RS10215	comGA/cglA/cilD	2033437..2034378 (+)	942	WP_050104907.1	competence type IV pilus ATPase ComGA	Machinery gene
R4699_RS10220	comGB/cglB	2034326..2035342 (+)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
R4699_RS10225	comGC/cglC	2035344..2035667 (+)	324	WP_000738628.1	comG operon protein ComGC	Machinery gene
R4699_RS10230	comGD/cglD	2035630..2036064 (+)	435	WP_000608686.1	competence type IV pilus minor pilin ComGD	Machinery gene
R4699_RS10235	comGE/cglE	2036027..2036329 (+)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R4699_RS10240	comGF/cglF	2036292..2036753 (+)	462	WP_000250520.1	competence type IV pilus minor pilin ComGF	Machinery gene
R4699_RS10245	comGG/cglG	2036731..2037144 (+)	414	WP_000265615.1	competence type IV pilus minor pilin ComGG	Machinery gene
R4699_RS10250	-	2037281..2037868 (+)	588	WP_000679776.1	class I SAM-dependent methyltransferase	-
R4699_RS10255	comYH	2037929..2038882 (+)	954	WP_044813830.1	class I SAM-dependent methyltransferase	Machinery gene
R4699_RS10260	-	2038933..2040123 (+)	1191	WP_050085692.1	acetate kinase	-
R4699_RS10265	-	2040124..2040255 (+)	132	WP_000768904.1	hypothetical protein	-
R4699_RS10270	rnpA	2040272..2040643 (+)	372	WP_000739246.1	ribonuclease P protein component	-
R4699_RS10275	-	2040618..2041442 (+)	825	WP_000727904.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 137 a.a.
• Molecular weight: 15888.28 Da
• Isoelectric Point: 10.1695

>NTDB_id=895518 R4699_RS10245 WP_000265615.1 2036731..2037144(+) (comGG/cglG) [Streptococcus pneumoniae strain 16H2092]
MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNKEKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKK
TSLVTTVRTDKSQYEFLFPSVKIKEEKRDKKEEVATDSSEKAEKKKSEEKPEKKENS

Nucleotide

• Length: 414 bp

>NTDB_id=895518 R4699_RS10245 WP_000265615.1 2036731..2037144(+) (comGG/cglG) [Streptococcus pneumoniae strain 16H2092]
GTGTGGAAAAAGAAGAAAGTTAAGGCAGGTGTTCTCCTCTACGCAGTCACCATAGCAGCCATCTTTAGTCTTTTGTTACA
ATTTTACTTGAACCGACAAATCGCCCACTATCAAGACTATGCTTTAAATAAAGAAAAGTTGGTTGCTTTTGCCATGGCCA
AGCGAACCAAGGATAAAGCCGAGCAAGAAAGTGGGGAACAGGTCTTTAATCTAGGTCAGGTAAGCTATCAAAACAAGAAA
ACAAGCTTGGTGACGACTGTTCGTACGGATAAGAGTCAATATGAGTTTCTGTTTCCTTCAGTCAAAATCAAAGAAGAGAA
AAGAGATAAAAAGGAAGAGGTAGCGACTGATTCAAGCGAAAAAGCGGAGAAGAAAAAATCAGAAGAGAAGCCTGAAAAGA
AAGAGAATTCCTAG

Domains

No domain identified.

3D structure

• AlphaFold DB: C1CA94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGG/cglG	Streptococcus mitis SK321	86.861	100	0.869
comGG/cglG	Streptococcus pneumoniae Rx1	95.726	85.401	0.818
comGG/cglG	Streptococcus pneumoniae D39	95.726	85.401	0.818
comGG/cglG	Streptococcus pneumoniae R6	95.726	85.401	0.818
comGG/cglG	Streptococcus pneumoniae TIGR4	95.726	85.401	0.818
comGG/cglG	Streptococcus mitis NCTC 12261	89.344	89.051	0.796
comYG	Streptococcus mutans UA140	38.806	97.81	0.38
comYG	Streptococcus mutans UA159	38.806	97.81	0.38