Detailed information NTG0802995

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: P3U27_RS04080
• Genome accession: NZ_CP120107
• Coordinates: 919027..920070 (+)
• Length: 347 a.a.
• NCBI ID: WP_014613481.1
• Uniprot ID: -
• Organism: Staphylococcus pseudintermedius strain Dog106
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 914027..925070

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P3U27_RS04055 (P3U27_04055)	-	914282..915004 (+)	723	WP_014613476.1	type 1 glutamine amidotransferase	-
P3U27_RS04060 (P3U27_04060)	-	915973..916971 (-)	999	WP_014613477.1	FUSC family protein	-
P3U27_RS04065 (P3U27_04065)	map	917068..917829 (+)	762	WP_014613478.1	type I methionyl aminopeptidase	-
P3U27_RS04070 (P3U27_04070)	-	917927..918316 (+)	390	WP_014613479.1	hypothetical protein	-
P3U27_RS04075 (P3U27_04075)	liaF	918329..919030 (+)	702	WP_014613480.1	cell wall-active antibiotics response protein LiaF	-
P3U27_RS04080 (P3U27_04080)	vraS	919027..920070 (+)	1044	WP_014613481.1	sensor histidine kinase	Regulator
P3U27_RS04085 (P3U27_04085)	vraR	920060..920689 (+)	630	WP_014613482.1	response regulator transcription factor	Regulator
P3U27_RS04090 (P3U27_04090)	-	921256..921837 (-)	582	WP_070407816.1	beta-class carbonic anhydrase	-
P3U27_RS04095 (P3U27_04095)	-	921870..923207 (-)	1338	WP_015729387.1	YihY/virulence factor BrkB family protein	-
P3U27_RS04100 (P3U27_04100)	-	923423..923710 (-)	288	WP_014613485.1	YtxH domain-containing protein	-
P3U27_RS04105 (P3U27_04105)	-	923718..924176 (-)	459	WP_014613486.1	low molecular weight protein-tyrosine-phosphatase	-
P3U27_RS04110 (P3U27_04110)	-	924310..924513 (+)	204	WP_014613487.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39939.24 Da
• Isoelectric Point: 5.0435

>NTDB_id=802995 P3U27_RS04080 WP_014613481.1 919027..920070(+) (vraS) [Staphylococcus pseudintermedius strain Dog106]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWLKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDEKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=802995 P3U27_RS04080 WP_014613481.1 919027..920070(+) (vraS) [Staphylococcus pseudintermedius strain Dog106]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTCTTTATTGACAA
AGTGTTCACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGTATTCCTGTTTTTATCTTTTTAAATT
TAGTCGTCATTTTTTTATGTATTATTGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGCTCAAGCAA
CAAATCGTTCGTGCCTTTGAAGGTGAAACAGTGGGCATCAATGATCAACAACTCGAGCTGTATAATGAAACGATTGAATT
ATATCAAGCACTCGTCCCATTAAATCAAGAATTGCATAAAATGCGAATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATAGAAGATGAACGACAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAAGAAACAGATTTAGCACCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGCGCTCTGTTACTTCACTTGAGACCTATAGGATTGAAGG
ACAAATCGTTAGGTGAGGGAATTAAATCGCTTGTGACGGATCTACAACGTAAAGTACCCATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTACCTAAAGGCATTGAGGATCACCTTTTTAGAATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGGACGCAAGTAACGGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTG
GATTTAATGTCGATGAAAAGTTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACA
TTTCATATCGTCTCATTACCTGATGCGGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	83.862	100	0.839