Detailed information NTG0075329

Bioinformatically predicted

Overview

• Name: comX/sigX/comX2/sigX2
• Type: Regulator
• Locus tag: UKS_RS01180
• Genome accession: NZ_AP021887
• Coordinates: 230531..231010 (+)
• Length: 159 a.a.
• NCBI ID: WP_156011438.1
• Uniprot ID: A0A6H3SIM9
• Organism: Streptococcus sp. 116-D4
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 225531..236010

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UKS_RS01155 (UKS_02110)	-	226274..227149 (-)	876	WP_080977087.1	RluA family pseudouridine synthase	-
UKS_RS01160 (UKS_02120)	pbp2a	227236..229431 (+)	2196	WP_156011437.1	penicillin-binding protein PBP2A	-
UKS_RS01165 (UKS_02130)	rpmG	229484..229636 (+)	153	WP_001809375.1	50S ribosomal protein L33	-
UKS_RS01170 (UKS_02140)	secE	229646..229822 (+)	177	WP_001210990.1	preprotein translocase subunit SecE	-
UKS_RS01175 (UKS_02150)	nusG	229876..230412 (+)	537	WP_033687381.1	transcription termination/antitermination protein NusG	-
UKS_RS01180 (UKS_02160)	comX/sigX/comX2/sigX2	230531..231010 (+)	480	WP_156011438.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

• Length: 159 a.a.
• Molecular weight: 20212.96 Da
• Isoelectric Point: 7.8710

>NTDB_id=75329 UKS_RS01180 WP_156011438.1 230531..231010(+) (comX/sigX/comX2/sigX2) [Streptococcus sp. 116-D4]
MFKELYKEVQGIVYKCRNEYYLHLWELSDWDQEGMICLHELISREEELAEDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGEISHRISEEGLWLDDYYLFHERLRDYRSKQNKEKQEELERLLRNERFRGRQRVLRDLRIVFKDFDIRTY

Nucleotide

• Length: 480 bp

>NTDB_id=75329 UKS_RS01180 WP_156011438.1 230531..231010(+) (comX/sigX/comX2/sigX2) [Streptococcus sp. 116-D4]
ATGTTTAAAGAATTGTATAAAGAAGTCCAAGGAATTGTGTATAAGTGTAGAAATGAGTATTACCTTCATTTATGGGAGCT
ATCGGATTGGGATCAAGAAGGTATGATTTGCTTGCATGAATTAATTAGTAGAGAAGAAGAGCTGGCAGAAGATATTCCTC
GATTAAGGAAGTACTTCAAAACTAAGTTCCGGAATCGTATTTTAGATTATATCCGTAAGCAGGAAAGTCAAAAACGAAGA
TATGATAAAGAACCGTATGAAGAAGTGGGTGAGATCAGTCATCGTATCAGTGAGGAAGGTCTTTGGCTAGATGACTATTA
TCTCTTTCATGAAAGACTAAGAGATTATAGAAGTAAACAAAATAAAGAGAAACAAGAGGAGTTAGAACGCCTCCTCAGAA
ATGAACGCTTTCGAGGCCGTCAAAGGGTCCTAAGAGACTTACGGATTGTGTTTAAAGATTTTGACATCCGTACATACTAG

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A6H3SIM9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	93.038	99.371	0.925
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	92.405	99.371	0.918
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	91.195	100	0.912
comX/comX1	Streptococcus pneumoniae Rx1	89.937	100	0.899
comX/comX2	Streptococcus pneumoniae D39	89.937	100	0.899
comX/comX2	Streptococcus pneumoniae R6	89.937	100	0.899
comX/comX1	Streptococcus pneumoniae R6	89.937	100	0.899
comX/comX1	Streptococcus pneumoniae D39	89.937	100	0.899
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	89.937	100	0.899
comX/comX2	Streptococcus pneumoniae Rx1	89.937	100	0.899
comX/comX2	Streptococcus pneumoniae TIGR4	89.308	100	0.893
comX/comX1	Streptococcus pneumoniae TIGR4	89.308	100	0.893
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	51.923	98.113	0.509
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	51.923	98.113	0.509
comX/sigX	Streptococcus mutans UA159	47.059	96.226	0.453
comX/sigX	Streptococcus suis D9	45.098	96.226	0.434
comX/sigX	Streptococcus suis isolate S10	45.098	96.226	0.434
comX/sigX	Streptococcus suis P1/7	45.098	96.226	0.434
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	42.953	93.711	0.403
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42.953	93.711	0.403
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42.953	93.711	0.403
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	42.953	93.711	0.403
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	42.105	95.597	0.403
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	42.105	95.597	0.403
comX	Streptococcus sobrinus strain NIDR 6715-7	40.26	96.855	0.39
comX	Streptococcus thermophilus LMD-9	38.71	97.484	0.377
comX	Streptococcus salivarius SK126	38.71	97.484	0.377
comX	Streptococcus thermophilus LMG 18311	38.71	97.484	0.377
comX/sigX	Streptococcus salivarius strain HSISS4	38.065	97.484	0.371