Detailed information NTG0075315

Bioinformatically predicted

Overview

• Name: comX/sigX/comX2/sigX2
• Type: Regulator
• Locus tag: UKS_RS00065
• Genome accession: NZ_AP021887
• Coordinates: 14454..14933 (+)
• Length: 159 a.a.
• NCBI ID: WP_156011309.1
• Uniprot ID: A0A6H3SG54
• Organism: Streptococcus sp. 116-D4
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 9454..19933

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UKS_RS00050 (UKS_00110)	tilS	10536..11813 (+)	1278	WP_156011307.1	tRNA lysidine(34) synthetase TilS	-
UKS_RS00055 (UKS_00120)	hpt	11818..12360 (+)	543	WP_156011308.1	hypoxanthine phosphoribosyltransferase	-
UKS_RS00060 (UKS_00130)	ftsH	12376..14334 (+)	1959	WP_049496515.1	ATP-dependent zinc metalloprotease FtsH	-
UKS_RS00065 (UKS_00140)	comX/sigX/comX2/sigX2	14454..14933 (+)	480	WP_156011309.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

• Length: 159 a.a.
• Molecular weight: 20147.84 Da
• Isoelectric Point: 7.3798

>NTDB_id=75315 UKS_RS00065 WP_156011309.1 14454..14933(+) (comX/sigX/comX2/sigX2) [Streptococcus sp. 116-D4]
MFKELYKEVQGIVYKCRNEYYLHLWELSDWDQEGMICLHELISREEELTEDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGEISHRISEDGLWLDDYYLFHETLRDYRSKQNKEKQEELERILRNERFRGRQRVLRDLRIVFKDFDIRTH

Nucleotide

• Length: 480 bp

>NTDB_id=75315 UKS_RS00065 WP_156011309.1 14454..14933(+) (comX/sigX/comX2/sigX2) [Streptococcus sp. 116-D4]
ATGTTTAAAGAATTGTATAAAGAAGTCCAGGGAATTGTGTATAAGTGTAGAAATGAGTATTACCTTCATTTATGGGAGTT
ATCGGATTGGGATCAAGAAGGTATGATTTGCTTGCATGAATTGATTAGTAGAGAAGAAGAGCTGACAGAAGATATCCCTC
GATTAAGGAAGTACTTCAAAACTAAGTTCCGAAATCGTATTTTAGATTATATCCGTAAGCAGGAAAGTCAAAAACGAAGA
TATGATAAAGAACCGTATGAAGAAGTTGGTGAGATCAGTCATCGTATCAGTGAGGATGGCCTCTGGCTAGATGACTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAGTAAACAAAATAAAGAGAAACAAGAAGAGTTAGAACGCATCCTCAGGA
ATGAACGCTTTCGGGGCCGTCAAAGGGTCCTAAGAGACTTACGAATTGTGTTTAAAGATTTTGACATCCGTACCCACTAG

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A6H3SG54

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	93.082	100	0.931
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	92.453	100	0.925
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	92.405	99.371	0.918
comX/comX1	Streptococcus pneumoniae Rx1	91.195	100	0.912
comX/comX2	Streptococcus pneumoniae D39	91.195	100	0.912
comX/comX1	Streptococcus pneumoniae D39	91.195	100	0.912
comX/comX1	Streptococcus pneumoniae R6	91.195	100	0.912
comX/comX2	Streptococcus pneumoniae R6	91.195	100	0.912
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	91.195	100	0.912
comX/comX2	Streptococcus pneumoniae Rx1	91.195	100	0.912
comX/comX2	Streptococcus pneumoniae TIGR4	90.566	100	0.906
comX/comX1	Streptococcus pneumoniae TIGR4	90.566	100	0.906
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	51.282	98.113	0.503
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	51.282	98.113	0.503
comX/sigX	Streptococcus mutans UA159	46.405	96.226	0.447
comX/sigX	Streptococcus suis D9	44.444	96.226	0.428
comX/sigX	Streptococcus suis isolate S10	44.444	96.226	0.428
comX/sigX	Streptococcus suis P1/7	44.444	96.226	0.428
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	42.282	93.711	0.396
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42.282	93.711	0.396
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42.282	93.711	0.396
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	42.282	93.711	0.396
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	41.447	95.597	0.396
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	41.447	95.597	0.396
comX	Streptococcus sobrinus strain NIDR 6715-7	38.961	96.855	0.377
comX	Streptococcus thermophilus LMD-9	38.065	97.484	0.371
comX	Streptococcus salivarius SK126	38.065	97.484	0.371
comX	Streptococcus thermophilus LMG 18311	38.065	97.484	0.371
comX/sigX	Streptococcus salivarius strain HSISS4	37.419	97.484	0.365