Detailed information NTG0737537

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: ODS73_RS02945
• Genome accession: NZ_CP107038
• Coordinates: 552970..555123 (-)
• Length: 717 a.a.
• NCBI ID: WP_284060617.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain BM6001
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 547970..560123

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ODS73_RS02915 (ODS73_02915)	-	548303..548632 (-)	330	WP_000132575.1	hypothetical protein	-
ODS73_RS02920 (ODS73_02920)	-	548908..549246 (+)	339	WP_284060616.1	LytTR family DNA-binding domain-containing protein	-
ODS73_RS02925 (ODS73_02925)	comE/blpR	549251..549988 (+)	738	WP_001219126.1	response regulator transcription factor	Regulator
ODS73_RS02930 (ODS73_02930)	-	550001..551341 (+)	1341	WP_000275284.1	sensor histidine kinase	-
ODS73_RS02935 (ODS73_02935)	blpC	551386..551541 (-)	156	WP_000358814.1	quorum-sensing system pheromone BlpC	-
ODS73_RS02940 (ODS73_02940)	-	551598..552959 (-)	1362	WP_001069099.1	bacteriocin secretion accessory protein	-
ODS73_RS02945 (ODS73_02945)	comA/nlmT	552970..555123 (-)	2154	WP_284060617.1	peptide cleavage/export ABC transporter BlpA	Regulator
ODS73_RS02950 (ODS73_02950)	-	555398..555646 (+)	249	WP_001093269.1	Blp family class II bacteriocin	-
ODS73_RS02955 (ODS73_02955)	-	555662..555871 (+)	210	WP_000483697.1	Blp family class II bacteriocin	-
ODS73_RS02960 (ODS73_02960)	-	556949..557053 (+)	105	Protein_584	IS30 family transposase	-
ODS73_RS02965 (ODS73_02965)	-	557073..557648 (+)	576	WP_000497530.1	CPBP family intramembrane glutamic endopeptidase	-
ODS73_RS02970 (ODS73_02970)	-	557842..558063 (+)	222	WP_001821291.1	hypothetical protein	-
ODS73_RS02975 (ODS73_02975)	-	558093..558497 (+)	405	WP_000717930.1	hypothetical protein	-
ODS73_RS02980 (ODS73_02980)	-	559299..560102 (+)	804	Protein_588	IS5 family transposase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80772.77 Da
• Isoelectric Point: 7.4163

>NTDB_id=737537 ODS73_RS02945 WP_284060617.1 552970..555123(-) (comA/nlmT) [Streptococcus pneumoniae strain BM6001]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKECFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMF
IIFSFMKPFEKMNHDVMQSNSIVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKL
VLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFL
MGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=737537 ODS73_RS02945 WP_284060617.1 552970..555123(-) (comA/nlmT) [Streptococcus pneumoniae strain BM6001]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGCGGTGTTGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAATGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCTTCCTTCCTCTG
ATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTA
TTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTA
TCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAGAGATTAAGTATTGAT
GTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCTATGTCTTTCTTTGCAACACGTCGTACAGGAGAAATCATTTC
ACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGA
TTCTTGTAGGGGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATGTTC
ATCATCTTTTCTTTTATGAAGCCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATAGTTAGCTCTGCCAT
TATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAAT
TTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTACCTT
TAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCG
CTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTG
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCT
TTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATT
AATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAATTTAACCTTGGGCGGTAATCATATGATTAG
CCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTC
AGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAATCTCCT
GTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGGGGA
AAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTGTTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	71.888	99.721	0.717
comA	Streptococcus mitis NCTC 12261	66.48	99.442	0.661
comA	Streptococcus pneumoniae Rx1	65.919	99.442	0.656
comA	Streptococcus pneumoniae R6	65.919	99.442	0.656
comA	Streptococcus pneumoniae D39	65.919	99.442	0.656
comA	Streptococcus mitis SK321	65.919	99.442	0.656
comA	Streptococcus gordonii str. Challis substr. CH1	65.181	100	0.653
comA	Streptococcus pneumoniae TIGR4	65.638	99.442	0.653