Detailed information NTG0657310

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OHU26_RS14265
• Genome accession: NZ_CP108249
• Coordinates: 3244538..3245662 (+)
• Length: 374 a.a.
• NCBI ID: WP_266626819.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00069
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3239538..3250662

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHU26_RS14250 (OHU26_14205)	-	3240216..3240965 (+)	750	WP_389874932.1	hypothetical protein	-
OHU26_RS14255 (OHU26_14210)	-	3240991..3242709 (-)	1719	WP_327362004.1	BACON domain-containing protein	-
OHU26_RS14260 (OHU26_14215)	radA/sms	3242881..3244284 (+)	1404	WP_266626817.1	DNA repair protein RadA	Machinery gene
OHU26_RS14265 (OHU26_14220)	disA	3244538..3245662 (+)	1125	WP_266626819.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OHU26_RS14270 (OHU26_14225)	-	3245684..3246472 (-)	789	WP_405706326.1	hypothetical protein	-
OHU26_RS14275 (OHU26_14230)	-	3246642..3247256 (+)	615	WP_362630653.1	phosphatase PAP2 family protein	-
OHU26_RS14280 (OHU26_14235)	-	3247280..3248233 (+)	954	WP_266626824.1	A/G-specific adenine glycosylase	-
OHU26_RS14285 (OHU26_14240)	-	3248417..3248989 (+)	573	WP_030158464.1	SigE family RNA polymerase sigma factor	-
OHU26_RS14290 (OHU26_14245)	-	3249028..3249666 (+)	639	WP_327364543.1	hypothetical protein	-
OHU26_RS14295 (OHU26_14250)	cseB	3249729..3250442 (+)	714	WP_266626826.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40362.36 Da
• Isoelectric Point: 5.0260

>NTDB_id=657310 OHU26_RS14265 WP_266626819.1 3244538..3245662(+) (disA) [Streptomyces sp. NBC_00069]
MAAKDGAAASGKSGASSKQEAMMRASLSAVAPGQPLRDGLERIVRGNTGGLIVLGMDKSVEAMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDITKILRAGVQLVPDASIPTEETGTRHRTADRVSKQCGFPVVSVSQSMRLIALYVDGERRVLEESGA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELTV
GIEQERELVIRDYVPEPTAKRSRTVEEALPALDALTHPELLELGIVARALGYTGSPETLDSAVSPRGYRLLAKIPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=657310 OHU26_RS14265 WP_266626819.1 3244538..3245662(+) (disA) [Streptomyces sp. NBC_00069]
GTGGCAGCCAAGGACGGGGCAGCAGCATCCGGAAAGTCGGGCGCGAGCTCCAAGCAGGAGGCCATGATGCGCGCCTCGCT
GAGCGCGGTCGCACCTGGTCAGCCCCTGCGTGACGGTCTGGAACGGATCGTCCGCGGCAACACCGGCGGCCTCATCGTCC
TCGGGATGGACAAGAGCGTCGAGGCGATGTGCACGGGCGGTTTCGTCCTGGACGTGGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGCGCTGATCCTGGACAAGGACATCACCAAGATCCTGCGGGCCGGCGTCCAGCTGGTGCC
GGACGCGTCGATCCCGACGGAGGAGACGGGCACCCGTCACCGCACCGCGGACCGCGTCTCGAAGCAGTGCGGGTTCCCCG
TGGTGTCGGTGTCGCAGTCGATGCGGTTGATCGCGCTGTACGTGGACGGGGAGCGCCGGGTCCTGGAGGAGTCCGGGGCG
ATCCTGTCGCGGGCGAACCAGGCGCTGGCCACGCTGGAGCGGTACAAGCTACGGCTCGACGAGGTCGCGGGGACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTCACGGTGCGCGACGTGACGGCGGTCGCGCAGCGGCTGGAAATGGTGCGCCGCATTG
CCACGGAAATCGCTGAATACGTGGTCGAGCTGGGCACGGACGGGCGACTGCTGTCGCTCCAGCTGGACGAGCTGACGGTC
GGCATCGAGCAGGAGCGGGAGCTGGTGATCCGGGACTATGTGCCGGAGCCGACGGCGAAGCGCTCCCGCACGGTGGAGGA
GGCGCTGCCGGCGCTGGACGCGCTGACGCATCCGGAGCTGCTGGAGCTCGGGATCGTGGCGCGGGCGCTGGGGTACACGG
GCTCGCCGGAGACGCTCGACTCGGCGGTGTCCCCGCGGGGGTACCGGCTGCTGGCGAAGATTCCGCGGCTGCCGGGGGCC
ATCATCGAGCGGCTGGTGGAGCACTTCGGGGGCCTGCAGAAGCTGCTGGCCGCGTCGGTGGACGATCTGCAGACGGTCGA
CGGGGTCGGGGAAGCCCGTGCGCGCAGCGTCCGCGAGGGCCTGTCCCGCCTGGCGGAGTCCTCGATCCTCGAGCGCTACG
TCTGA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.983	96.524	0.444