Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR/comR2   Type   Regulator
Locus tag   SIR_RS18590 Genome accession   NC_022246
Coordinates   1824091..1824564 (-) Length   157 a.a.
NCBI ID   WP_021002266.1    Uniprot ID   T1ZGJ1
Organism   Streptococcus intermedius B196     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1819091..1829564
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIR_RS18590 (SIR_1732) comR/comR2 1824091..1824564 (-) 474 WP_021002266.1 competence-specific global transcription modulator Regulator
  SIR_RS18600 (SIR_1733) rplQ 1825491..1825877 (-) 387 WP_003075160.1 50S ribosomal protein L17 -
  SIR_RS18605 (SIR_1734) - 1825889..1826827 (-) 939 WP_020999215.1 DNA-directed RNA polymerase subunit alpha -
  SIR_RS18610 (SIR_1735) rpsK 1826872..1827255 (-) 384 WP_001118385.1 30S ribosomal protein S11 -
  SIR_RS18615 (SIR_1736) rpsM 1827275..1827640 (-) 366 WP_002262317.1 30S ribosomal protein S13 -
  SIR_RS19775 (SIR_1737) rpmJ 1827656..1827772 (-) 117 WP_001808836.1 50S ribosomal protein L36 -
  SIR_RS18620 (SIR_1738) infA 1827797..1828015 (-) 219 WP_001029883.1 translation initiation factor IF-1 -
  SIR_RS18625 (SIR_1739) - 1828131..1828769 (-) 639 WP_009569575.1 adenylate kinase -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19418.41 Da        Isoelectric Point: 8.6124

>NTDB_id=61919 SIR_RS18590 WP_021002266.1 1824091..1824564(-) (comR/comR2) [Streptococcus intermedius B196]
MDFKELYEKVRGIVLKCRREYYVHLWELSDWDQEGMMVLYELVSRHPYLVEEEAHLYVYYKTKFRNHIKDILRKQESQKR
KLDRQVYEEVSEIGHKLSLKGLYLDELVILRDQLKSYQKQLSPAKQEQYERLLADERFKGRQAMLRELRTYLKDYEM

Nucleotide


Download         Length: 474 bp        

>NTDB_id=61919 SIR_RS18590 WP_021002266.1 1824091..1824564(-) (comR/comR2) [Streptococcus intermedius B196]
ATGGATTTCAAGGAGTTATATGAGAAAGTAAGGGGAATTGTGCTGAAGTGTCGGCGGGAATATTATGTCCACCTGTGGGA
GCTAAGCGATTGGGACCAAGAAGGGATGATGGTCTTGTATGAGTTGGTGAGTCGCCACCCCTATTTGGTAGAGGAAGAAG
CCCATCTCTATGTTTACTATAAGACAAAGTTTCGGAATCACATAAAGGATATTCTGCGCAAACAAGAAAGTCAAAAGCGC
AAACTGGATCGCCAAGTGTATGAAGAGGTAAGTGAGATTGGGCACAAGTTAAGTCTGAAAGGTCTGTATCTAGACGAGTT
GGTAATACTCCGCGATCAATTAAAGTCCTATCAAAAGCAACTGAGTCCCGCCAAGCAAGAGCAGTATGAGCGGTTACTGG
CAGATGAAAGGTTCAAAGGCCGCCAAGCGATGCTTCGAGAGTTACGAACCTACTTAAAAGACTATGAGATGTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB T1ZGJ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

60.645

98.726

0.599
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

60.645

98.726

0.599
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

56.774

98.726

0.561
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

55.484

98.726

0.548
  comX/comX1 Streptococcus pneumoniae Rx1

54.839

98.726

0.541
  comX/comX2 Streptococcus pneumoniae D39

54.839

98.726

0.541
  comX/comX1 Streptococcus pneumoniae D39

54.839

98.726

0.541
  comX/comX1 Streptococcus pneumoniae R6

54.839

98.726

0.541
  comX/comX2 Streptococcus pneumoniae R6

54.839

98.726

0.541
  comX/comX2 Streptococcus pneumoniae Rx1

54.839

98.726

0.541
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

54.839

98.726

0.541
  comX/comX1 Streptococcus pneumoniae TIGR4

54.194

98.726

0.535
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

54.194

98.726

0.535
  comX/comX2 Streptococcus pneumoniae TIGR4

54.194

98.726

0.535
  comX/sigX Streptococcus mutans UA159

50.649

98.089

0.497
  comX/sigX Streptococcus suis D9

49.032

98.726

0.484
  comX/sigX Streptococcus suis isolate S10

49.032

98.726

0.484
  comX/sigX Streptococcus suis P1/7

49.032

98.726

0.484
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

43.226

98.726

0.427
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

43.226

98.726

0.427
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

43.226

98.726

0.427
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

43.226

98.726

0.427
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

43.226

98.726

0.427
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

43.226

98.726

0.427
  comX Streptococcus salivarius SK126

42.857

98.089

0.42
  comX Streptococcus thermophilus LMG 18311

42.208

98.089

0.414
  comX Streptococcus thermophilus LMD-9

42.208

98.089

0.414
  comX/sigX Streptococcus salivarius strain HSISS4

42.208

98.089

0.414
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

39.744

99.363

0.395

Multiple sequence alignment