Detailed information NTG0061867

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: SIR_RS11345
• Genome accession: NC_022246
• Coordinates: 310639..311121 (+)
• Length: 160 a.a.
• NCBI ID: WP_021002446.1
• Uniprot ID: T1ZCU4
• Organism: Streptococcus intermedius B196
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 305639..316121

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SIR_RS11320 (SIR_0311)	-	307107..307862 (-)	756	WP_021002443.1	hypothetical protein	-
SIR_RS11325 (SIR_0312)	-	308010..309071 (+)	1062	WP_021002444.1	M24 family metallopeptidase	-
SIR_RS11330 (SIR_0313)	efp	309130..309690 (+)	561	WP_003026309.1	elongation factor P	-
SIR_RS11335 (SIR_0314)	-	309800..310189 (+)	390	WP_003074522.1	Asp23/Gls24 family envelope stress response protein	-
SIR_RS11340 (SIR_0315)	nusB	310182..310607 (+)	426	WP_041787361.1	transcription antitermination factor NusB	-
SIR_RS11345 (SIR_0316)	comR/comR2	310639..311121 (+)	483	WP_021002446.1	hypothetical protein	Regulator

Sequence

Protein

• Length: 160 a.a.
• Molecular weight: 19790.92 Da
• Isoelectric Point: 9.4017

>NTDB_id=61867 SIR_RS11345 WP_021002446.1 310639..311121(+) (comR/comR2) [Streptococcus intermedius B196]
MRSPLFYKLYEKVRGIVLKCRREYYVHLWELSDWDQEGMMVLYELVSRHPYLVEEEAHLYVYYKTKFRNHIKDILRKQES
QKRKLDRQVYEEVSEIGHKLSLKGLYLDELVILRDQLKSYQKQLSPAKQEQYERLLADERFKGRQAMLRELRTYLKDYEM

Nucleotide

• Length: 483 bp

>NTDB_id=61867 SIR_RS11345 WP_021002446.1 310639..311121(+) (comR/comR2) [Streptococcus intermedius B196]
GTGCGAAGTCCTCTTTTTTATAAGTTATATGAGAAAGTAAGGGGAATTGTGCTGAAGTGTCGGCGGGAATATTATGTCCA
CCTGTGGGAGCTAAGCGATTGGGACCAAGAAGGGATGATGGTCTTGTATGAGTTGGTGAGTCGCCACCCCTATTTGGTAG
AGGAAGAAGCCCATCTCTATGTTTACTATAAGACAAAGTTTCGGAATCACATAAAGGATATTCTGCGCAAACAAGAAAGT
CAAAAGCGCAAACTGGATCGCCAAGTGTATGAAGAGGTAAGTGAGATTGGGCACAAGTTAAGTCTGAAAGGTCTGTATCT
AGACGAGTTGGTAATACTCCGCGATCAATTAAAGTCCTATCAAAAGCAACTGAGTCCCGCCAAGCAAGAGCAGTATGAGC
GGTTACTGGCAGATGAAAGGTTCAAAGGCCGCCAAGCGATGCTTCGAGAGTTACGAACCTACTTAAAAGACTATGAGATG
TAG

Domains

No domain identified.

3D structure

• AlphaFold DB: T1ZCU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	60.784	95.625	0.581
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	60.784	95.625	0.581
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	55.128	97.5	0.537
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	53.846	97.5	0.525
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	53.205	97.5	0.519
comX/comX1	Streptococcus pneumoniae Rx1	54.248	95.625	0.519
comX/comX2	Streptococcus pneumoniae D39	54.248	95.625	0.519
comX/comX1	Streptococcus pneumoniae D39	54.248	95.625	0.519
comX/comX2	Streptococcus pneumoniae R6	54.248	95.625	0.519
comX/comX1	Streptococcus pneumoniae R6	54.248	95.625	0.519
comX/comX2	Streptococcus pneumoniae Rx1	54.248	95.625	0.519
comX/comX1	Streptococcus pneumoniae TIGR4	53.595	95.625	0.513
comX/comX2	Streptococcus pneumoniae TIGR4	53.595	95.625	0.513
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	52.564	97.5	0.512
comX/sigX	Streptococcus mutans UA159	50.327	95.625	0.481
comX/sigX	Streptococcus suis isolate S10	49.673	95.625	0.475
comX/sigX	Streptococcus suis D9	49.673	95.625	0.475
comX/sigX	Streptococcus suis P1/7	49.673	95.625	0.475
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	44.667	93.75	0.419
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	44.667	93.75	0.419
comX	Streptococcus salivarius SK126	42.138	99.375	0.419
comX	Streptococcus thermophilus LMG 18311	42.138	99.375	0.419
comX	Streptococcus thermophilus LMD-9	42.138	99.375	0.419
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	44.966	93.125	0.419
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	44.966	93.125	0.419
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	44.966	93.125	0.419
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	44.966	93.125	0.419
comX/sigX	Streptococcus salivarius strain HSISS4	41.509	99.375	0.412
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	38.961	96.25	0.375