Detailed information    

insolico Bioinformatically predicted

Overview


Name   comR/comR2   Type   Regulator
Locus tag   SCIM_RS08520 Genome accession   NC_018073
Coordinates   1749492..1749965 (-) Length   157 a.a.
NCBI ID   WP_014829824.1    Uniprot ID   -
Organism   Streptococcus intermedius JTH08     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1741037..1749965 1749492..1749965 within 0


Gene organization within MGE regions


Location: 1741037..1749965
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCIM_RS08390 (SCIM_1524) - 1741037..1741444 (+) 408 WP_003073927.1 pyridoxamine 5'-phosphate oxidase family protein -
  SCIM_RS08395 (SCIM_1525) - 1741474..1741792 (-) 319 Protein_1644 winged helix-turn-helix transcriptional regulator -
  SCIM_RS08400 (SCIM_1526) - 1741905..1742366 (+) 462 Protein_1645 tyrosine-type recombinase/integrase -
  SCIM_RS08520 (SCIM_1527) comR/comR2 1749492..1749965 (-) 474 WP_014829824.1 hypothetical protein Regulator

Sequence


Protein


Download         Length: 157 a.a.        Molecular weight: 19347.33 Da        Isoelectric Point: 7.8842

>NTDB_id=51903 SCIM_RS08520 WP_014829824.1 1749492..1749965(-) (comR/comR2) [Streptococcus intermedius JTH08]
MDFKELYEKVRGIVLKCRREYYVHLWELSDWDQEGMIVLYELVSCHPYLVEEEAHLYVYYKTKFRNHIKDILRKQESQKR
KLDRQVYEEVSEIGHKLSLKGLYLDELVILRDQLKSYQKQLSPAKQEQYERLLADERFKGRQAMLRELRTYLKDYEM

Nucleotide


Download         Length: 474 bp        

>NTDB_id=51903 SCIM_RS08520 WP_014829824.1 1749492..1749965(-) (comR/comR2) [Streptococcus intermedius JTH08]
ATGGATTTCAAGGAGTTATATGAGAAAGTAAGGGGAATTGTGCTGAAGTGTCGGCGGGAATATTATGTCCATCTGTGGGA
GCTAAGCGATTGGGATCAAGAAGGGATGATAGTCTTGTATGAGTTGGTAAGTTGCCACCCCTATTTGGTAGAGGAAGAAG
CCCATCTCTATGTCTACTATAAGACAAAGTTTCGGAATCACATAAAGGATATTCTGCGCAAACAAGAAAGTCAAAAGCGC
AAACTGGATCGCCAAGTGTATGAAGAGGTAAGTGAGATTGGGCACAAGTTAAGTCTGAAAGGTCTGTATCTAGACGAGTT
GGTAATACTCCGCGATCAATTAAAGTCCTATCAAAAGCAACTGAGTCCCGCCAAGCAAGAGCAGTATGAGCGGTTACTGG
CAGATGAAAGGTTCAAAGGCCGCCAAGCGATGCTTCGAGAGTTACGAACCTACTTAAAAGACTATGAGATGTAG

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

60.645

98.726

0.599

  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

60.645

98.726

0.599

  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

56.774

98.726

0.561

  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

55.484

98.726

0.548

  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

54.839

98.726

0.541

  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

54.839

98.726

0.541

  comX/comX1 Streptococcus pneumoniae D39

54.194

98.726

0.535

  comX/comX1 Streptococcus pneumoniae R6

54.194

98.726

0.535

  comX/comX2 Streptococcus pneumoniae R6

54.194

98.726

0.535

  comX/comX2 Streptococcus pneumoniae Rx1

54.194

98.726

0.535

  comX/comX1 Streptococcus pneumoniae Rx1

54.194

98.726

0.535

  comX/comX2 Streptococcus pneumoniae D39

54.194

98.726

0.535

  comX/comX1 Streptococcus pneumoniae TIGR4

53.548

98.726

0.529

  comX/comX2 Streptococcus pneumoniae TIGR4

53.548

98.726

0.529

  comX/sigX Streptococcus mutans UA159

50.649

98.089

0.497

  comX/sigX Streptococcus suis D9

48.387

98.726

0.478

  comX/sigX Streptococcus suis isolate S10

48.387

98.726

0.478

  comX/sigX Streptococcus suis P1/7

48.387

98.726

0.478

  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

43.226

98.726

0.427

  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

43.226

98.726

0.427

  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

43.226

98.726

0.427

  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

43.226

98.726

0.427

  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

43.226

98.726

0.427

  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

43.226

98.726

0.427

  comX Streptococcus salivarius SK126

42.208

98.089

0.414

  comX/sigX Streptococcus salivarius strain HSISS4

41.558

98.089

0.408

  comX Streptococcus thermophilus LMG 18311

41.558

98.089

0.408

  comX Streptococcus thermophilus LMD-9

41.558

98.089

0.408

  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

40.385

99.363

0.401


Multiple sequence alignment