Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   JFJ84_RS07960 Genome accession   NZ_CP066739
Coordinates   1686429..1687649 (-) Length   406 a.a.
NCBI ID   WP_012341581.1    Uniprot ID   A0A9Q7E4C6
Organism   Histophilus somni strain ASc-MMNZ-VFA-069     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1681429..1692649
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JFJ84_RS07930 (JFJ84_07925) hpt 1681791..1682330 (-) 540 WP_011608620.1 hypoxanthine phosphoribosyltransferase -
  JFJ84_RS07935 (JFJ84_07930) raiA 1682534..1682851 (-) 318 WP_012341586.1 ribosome-associated translation inhibitor RaiA -
  JFJ84_RS07940 (JFJ84_07935) - 1683087..1684463 (-) 1377 WP_012341585.1 alanine/glycine:cation symporter family protein -
  JFJ84_RS07945 (JFJ84_07940) yacG 1684867..1685061 (-) 195 WP_011608616.1 DNA gyrase inhibitor YacG -
  JFJ84_RS07950 (JFJ84_07945) coaE 1685058..1685705 (-) 648 WP_012341582.1 dephospho-CoA kinase -
  JFJ84_RS07955 (JFJ84_07950) pilD 1685725..1686432 (-) 708 WP_011608614.1 prepilin peptidase Machinery gene
  JFJ84_RS07960 (JFJ84_07955) pilC 1686429..1687649 (-) 1221 WP_012341581.1 type II secretion system F family protein Machinery gene
  JFJ84_RS07980 (JFJ84_07975) gltX 1688346..1689788 (+) 1443 WP_012341580.1 glutamate--tRNA ligase -
  JFJ84_RS07990 (JFJ84_07985) - 1690127..1690861 (-) 735 WP_012341579.1 4'-phosphopantetheinyl transferase family protein -
  JFJ84_RS07995 (JFJ84_07990) - 1690900..1691142 (-) 243 WP_011608610.1 hypothetical protein -
  JFJ84_RS08000 (JFJ84_07995) - 1691366..1692502 (-) 1137 Protein_1564 RNA-guided endonuclease InsQ/TnpB family protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46702.12 Da        Isoelectric Point: 9.7933

>NTDB_id=455763 JFJ84_RS07960 WP_012341581.1 1686429..1687649(-) (pilC) [Histophilus somni strain ASc-MMNZ-VFA-069]
MQNLKLFSWKATNFLQQKQAGMLVIENVQEAKRYLLQQGLNNIYLQRHWQLNKKPKKIEFCDLLTQLAMLLQSSIPLKDS
LQILLRNCVNISLNQWVRYILKNLEGGLSFSQSVAQSGLYFSYQERQLISVGEMTGDLASVCQQIAEHRQQALALQRKIQ
KILLYPMIVLSISVILTALLLIFIVPQFAEMYGSNQSELPFFTQLLLNISSFLQQYFFHMIAVSILFFYLIKLRLHNSYS
FQLKKDWFLSHVPLLNKIIRLNRTISFCRSLGLMLNSGIPLQQSLYSFLPQNSINIQKKIEGDLTLINEVKLTLRGIEQG
YKFSQSVSSNLFSIQTQQMLQVGEKSGNLGLILQHIAENQQQQLDHQIDLLSQMLEPFMMVIIGGLIGLIMLGMYLPIFN
MGSLIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=455763 JFJ84_RS07960 WP_012341581.1 1686429..1687649(-) (pilC) [Histophilus somni strain ASc-MMNZ-VFA-069]
ATGCAGAATTTGAAGCTATTTTCTTGGAAAGCCACTAATTTTTTACAGCAAAAACAAGCTGGAATGCTTGTTATCGAAAA
TGTACAAGAGGCCAAACGCTATTTATTACAACAAGGGCTAAACAATATATATTTACAGCGTCATTGGCAACTGAATAAAA
AGCCTAAAAAAATAGAATTTTGTGATCTATTAACTCAATTAGCAATGTTATTACAATCCTCAATTCCTTTAAAAGATAGC
TTACAAATTTTATTGAGAAATTGTGTTAATATTTCTTTAAATCAATGGGTTAGATATATTTTAAAAAATCTTGAAGGAGG
ATTATCTTTTTCACAATCTGTGGCTCAATCAGGTCTATATTTTTCTTATCAAGAACGCCAACTCATTTCTGTTGGAGAAA
TGACGGGAGATTTAGCCTCTGTTTGCCAACAAATAGCAGAACATCGTCAGCAGGCATTAGCATTACAACGCAAAATTCAA
AAAATTTTACTCTATCCAATGATAGTCTTAAGTATTTCTGTCATTCTCACCGCACTTCTATTAATTTTTATCGTGCCACA
ATTTGCCGAAATGTACGGTTCTAATCAATCCGAGCTTCCTTTTTTTACGCAGCTATTGTTAAACATATCCTCTTTTTTAC
AACAGTATTTTTTTCATATGATAGCGGTATCTATTTTATTTTTTTATCTAATAAAATTACGTTTACACAATTCATATAGT
TTTCAACTCAAAAAAGATTGGTTTTTATCGCATGTGCCGTTGTTAAATAAAATTATTCGGCTTAATAGAACGATAAGTTT
TTGCCGTAGTTTAGGATTAATGCTCAACTCAGGCATTCCTTTACAACAAAGTCTATATTCTTTCCTTCCCCAAAACTCTA
TCAACATACAGAAAAAGATTGAGGGAGATCTCACGTTAATTAATGAAGTAAAGCTAACATTACGTGGTATCGAACAAGGA
TATAAATTCTCTCAGTCTGTAAGCAGTAATTTGTTTTCTATACAAACACAACAAATGCTACAAGTTGGTGAAAAGAGTGG
AAATCTAGGTTTAATTCTGCAACATATCGCAGAAAATCAGCAACAACAGTTAGATCATCAAATTGATTTACTTTCACAAA
TGTTAGAACCGTTTATGATGGTGATCATTGGCGGATTAATAGGCTTGATTATGTTAGGTATGTATTTACCAATCTTTAAT
ATGGGAAGTTTAATTCAATGA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)

Type II secretion system (T2SS), protein F (T2SSF)

(267-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9Q7E4C6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

53.431

100

0.537
  pilC Haemophilus influenzae 86-028NP

53.102

99.261

0.527
  pilC Glaesserella parasuis strain SC1401

39.901

100

0.399