Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   GE023_RS08065 Genome accession   NZ_CP053789
Coordinates   1621465..1621953 (-) Length   162 a.a.
NCBI ID   WP_039994770.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_98_2     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 1620361..1621314 1621465..1621953 flank 151


Gene organization within MGE regions


Location: 1620361..1621953
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE023_RS08060 (GE023_008055) - 1620361..1621314 (+) 954 WP_164401460.1 IS30 family transposase -
  GE023_RS08065 (GE023_008060) comX/sigX/comX2/sigX2 1621465..1621953 (-) 489 WP_039994770.1 hypothetical protein Regulator

Sequence

Protein


Download         Length: 162 a.a.        Molecular weight: 19678.57 Da        Isoelectric Point: 5.7359

>NTDB_id=447172 GE023_RS08065 WP_039994770.1 1621465..1621953(-) (comX/sigX/comX2/sigX2) [Streptococcus canis strain HL_98_2]
MDMSIETEVVFEKVKPIILKLKRHYYIQLWEREDWLQEGYLILVSLLEQHPELLWEDERLYRYFKTKFSSYLKDVLRQQE
SQKRQFHKMAYEEIGDVAHAIPSGGLWLDDYVAYREVVEVLEGQLGEEERLQFQALVRGERFKGRQALLRKLRPYFEGFE
RS

Nucleotide


Download         Length: 489 bp        

>NTDB_id=447172 GE023_RS08065 WP_039994770.1 1621465..1621953(-) (comX/sigX/comX2/sigX2) [Streptococcus canis strain HL_98_2]
ATGGACATGTCGATAGAGACAGAAGTAGTGTTTGAGAAGGTGAAACCCATTATCTTGAAGTTGAAGCGTCATTATTATAT
TCAATTGTGGGAGAGAGAGGATTGGTTACAGGAAGGGTATTTGATATTGGTGAGTCTTCTAGAGCAGCATCCTGAATTAC
TTTGGGAAGACGAACGGTTGTATCGTTATTTTAAGACTAAGTTTTCATCGTATTTGAAGGATGTCTTGCGTCAGCAAGAA
AGTCAGAAGCGTCAGTTTCATAAAATGGCTTATGAGGAGATAGGTGATGTAGCACATGCGATTCCATCAGGTGGGTTATG
GTTGGATGATTACGTGGCCTATAGGGAGGTGGTTGAGGTGTTAGAAGGGCAGTTGGGTGAAGAGGAGCGGTTACAGTTTC
AGGCCTTGGTGAGAGGGGAACGGTTTAAGGGAAGGCAGGCCTTGCTTAGGAAGTTGCGTCCTTATTTTGAGGGATTTGAG
AGAAGTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

77.987

98.148

0.765
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

77.987

98.148

0.765
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

77.358

98.148

0.759
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

77.358

98.148

0.759
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

76.73

98.148

0.753
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

76.73

98.148

0.753
  comX/sigX Streptococcus mutans UA159

51.899

97.531

0.506
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.077

96.296

0.463
  comX Streptococcus sobrinus strain NIDR 6715-7

42.857

99.383

0.426
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

41.667

96.296

0.401
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

41.667

96.296

0.401
  comX Streptococcus thermophilus LMD-9

43.046

93.21

0.401
  comX Streptococcus thermophilus LMG 18311

43.046

93.21

0.401
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

41.722

93.21

0.389
  comX/sigX Streptococcus salivarius strain HSISS4

41.06

93.21

0.383
  comX Streptococcus salivarius SK126

41.06

93.21

0.383
  comX/comX2 Streptococcus pneumoniae TIGR4

41.333

92.593

0.383
  comX/comX1 Streptococcus pneumoniae TIGR4

41.333

92.593

0.383
  comX/comX2 Streptococcus pneumoniae Rx1

41.333

92.593

0.383
  comX/comX1 Streptococcus pneumoniae Rx1

41.333

92.593

0.383
  comX/comX2 Streptococcus pneumoniae D39

41.333

92.593

0.383
  comX/comX1 Streptococcus pneumoniae D39

41.333

92.593

0.383
  comX/comX2 Streptococcus pneumoniae R6

41.333

92.593

0.383
  comX/comX1 Streptococcus pneumoniae R6

41.333

92.593

0.383
  comX/sigX Streptococcus suis D9

39.355

95.679

0.377
  comX/sigX Streptococcus suis isolate S10

39.355

95.679

0.377
  comX/sigX Streptococcus suis P1/7

39.355

95.679

0.377
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

40.397

93.21

0.377
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

40.397

93.21

0.377