Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   HKM25_RS10335 Genome accession   NZ_CP053210
Coordinates   2009722..2010048 (-) Length   108 a.a.
NCBI ID   WP_000738635.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 6A-10     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2004722..2015048
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HKM25_RS10295 (HKM25_2108) rnpA 2004740..2005111 (-) 372 WP_000739246.1 ribonuclease P protein component -
  HKM25_RS11980 (HKM25_2109) - 2005128..2005259 (-) 132 WP_000768904.1 hypothetical protein -
  HKM25_RS10300 (HKM25_2110) - 2005260..2006450 (-) 1191 WP_054362660.1 acetate kinase -
  HKM25_RS10305 (HKM25_2111) comYH 2006501..2007454 (-) 954 WP_000345121.1 class I SAM-dependent methyltransferase Machinery gene
  HKM25_RS10310 - 2007515..2008108 (-) 594 Protein_2026 methyltransferase domain-containing protein -
  HKM25_RS10315 (HKM25_2114) comGG/cglG 2008245..2008658 (-) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  HKM25_RS10320 (HKM25_2115) comGF/cglF 2008636..2009097 (-) 462 WP_000250545.1 competence type IV pilus minor pilin ComGF Machinery gene
  HKM25_RS10325 (HKM25_2116) comGE/cglE 2009060..2009362 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  HKM25_RS10330 (HKM25_2117) comGD/cglD 2009325..2009729 (-) 405 WP_000588005.1 competence type IV pilus minor pilin ComGD Machinery gene
  HKM25_RS10335 (HKM25_2118) comGC/cglC 2009722..2010048 (-) 327 WP_000738635.1 comG operon protein ComGC Machinery gene
  HKM25_RS10340 (HKM25_2119) comGB/cglB 2010050..2011066 (-) 1017 WP_078151629.1 competence type IV pilus assembly protein ComGB Machinery gene
  HKM25_RS10345 (HKM25_2120) comGA/cglA/cilD 2011014..2011955 (-) 942 WP_000249555.1 competence type IV pilus ATPase ComGA Machinery gene
  HKM25_RS10350 (HKM25_2121) - 2012031..2012396 (-) 366 WP_000286415.1 DUF1033 family protein -
  HKM25_RS10355 (HKM25_2122) - 2012547..2013605 (-) 1059 WP_000649466.1 zinc-dependent alcohol dehydrogenase family protein -
  HKM25_RS10360 (HKM25_2123) nagA 2013768..2014919 (-) 1152 WP_001134454.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12231.43 Da        Isoelectric Point: 10.0305

>NTDB_id=443477 HKM25_RS10335 WP_000738635.1 2009722..2010048(-) (comGC/cglC) [Streptococcus pneumoniae strain 6A-10]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKE
DGRITEEQAKAYKEYHDKNGVANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=443477 HKM25_RS10335 WP_000738635.1 2009722..2010048(-) (comGC/cglC) [Streptococcus pneumoniae strain 6A-10]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAGGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAA
GATGGACGCATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGTAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae D39

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae R6

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae TIGR4

95.37

100

0.954
  comGC/cglC Streptococcus mitis SK321

92.593

100

0.926
  comGC/cglC Streptococcus mitis NCTC 12261

91.176

94.444

0.861
  comYC Streptococcus gordonii str. Challis substr. CH1

71.875

88.889

0.639
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comGC Lactococcus lactis subsp. cremoris KW2

54.902

94.444

0.519
  comYC Streptococcus suis isolate S10

67.901

75

0.509
  comGC Staphylococcus aureus MW2

48.837

79.63

0.389
  comGC Staphylococcus aureus N315

48.837

79.63

0.389
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361