Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   ST64987_RS01470 Genome accession   NZ_CP049053
Coordinates   261167..262066 (+) Length   299 a.a.
NCBI ID   WP_011680720.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST64987     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 256167..267066
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST64987_RS01450 (ST64987_0253) trkA 257304..258653 (-) 1350 WP_014621137.1 Trk system potassium transporter TrkA -
  ST64987_RS01455 (ST64987_0254) - 258912..259451 (+) 540 WP_372585740.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  ST64987_RS01460 (ST64987_0255) - 259762..260319 (+) 558 WP_011680718.1 ECF transporter S component -
  ST64987_RS01465 (ST64987_0256) - 260322..260972 (+) 651 WP_011680719.1 phosphatase PAP2 family protein -
  ST64987_RS01470 (ST64987_0257) comR 261167..262066 (+) 900 WP_011680720.1 helix-turn-helix domain-containing protein Regulator
  ST64987_RS09925 - 262304..262885 (+) 582 Protein_230 cysteine peptidase family C39 domain-containing protein -
  ST64987_RS09930 comA 262870..263160 (+) 291 WP_194238295.1 ABC transporter transmembrane domain-containing protein Regulator
  ST64987_RS10035 comA 263503..263712 (+) 210 WP_002946147.1 hypothetical protein Regulator
  ST64987_RS10040 (ST64987_0260) - 263767..264335 (+) 569 Protein_233 ATP-binding cassette domain-containing protein -
  ST64987_RS10045 (ST64987_0261) - 264566..264754 (+) 189 WP_224103239.1 hypothetical protein -
  ST64987_RS10050 - 264722..265006 (-) 285 WP_232557103.1 hypothetical protein -
  ST64987_RS10055 - 265247..265549 (-) 303 WP_224103194.1 hypothetical protein -
  ST64987_RS10060 (ST64987_0262) - 265773..266144 (-) 372 WP_224103195.1 hypothetical protein -
  ST64987_RS01510 (ST64987_0263) - 266549..267064 (+) 516 WP_002949547.1 AmiS/UreI family transporter -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35271.71 Da        Isoelectric Point: 5.1073

>NTDB_id=424459 ST64987_RS01470 WP_011680720.1 261167..262066(+) (comR) [Streptococcus thermophilus strain ST64987]
MNLKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIVFASVLEDSVLEESIKAGKLADGL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=424459 ST64987_RS01470 WP_011680720.1 261167..262066(+) (comR) [Streptococcus thermophilus strain ST64987]
TTGAACTTAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTTTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAGTGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(11-66)

ComR tetratricopeptide (ComR_TPR)

(75-292)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus thermophilus LMD-9

100

100

1
  comR Streptococcus thermophilus LMG 18311

99.331

100

0.993
  comR Streptococcus salivarius strain HSISS4

94.649

100

0.946
  comR Streptococcus salivarius SK126

93.98

100

0.94
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

42.14

100

0.421
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

41.472

100

0.415