Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   GOM47_RS00915 Genome accession   NZ_CP046524
Coordinates   170613..170936 (+) Length   107 a.a.
NCBI ID   WP_235080778.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOT     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 165613..175936
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM47_RS00895 (GOM47_00895) nagA 166974..168125 (+) 1152 WP_001134447.1 N-acetylglucosamine-6-phosphate deacetylase -
  GOM47_RS00900 (GOM47_00900) - 168271..168636 (+) 366 WP_000286396.1 DUF1033 family protein -
  GOM47_RS00905 (GOM47_00905) comGA/cglA/cilD 168706..169647 (+) 942 WP_235080777.1 competence type IV pilus ATPase ComGA Machinery gene
  GOM47_RS00910 (GOM47_00910) comGB/cglB 169595..170611 (+) 1017 WP_235081262.1 competence type IV pilus assembly protein ComGB Machinery gene
  GOM47_RS00915 (GOM47_00915) comGC/cglC 170613..170936 (+) 324 WP_235080778.1 competence type IV pilus major pilin ComGC Machinery gene
  GOM47_RS00920 (GOM47_00920) comGD/cglD 170899..171333 (+) 435 WP_235080779.1 competence type IV pilus minor pilin ComGD Machinery gene
  GOM47_RS00925 (GOM47_00925) comGE/cglE 171296..171598 (+) 303 WP_235080780.1 competence type IV pilus minor pilin ComGE Machinery gene
  GOM47_RS00930 (GOM47_00930) comGF/cglF 171561..172022 (+) 462 WP_235080781.1 competence type IV pilus minor pilin ComGF Machinery gene
  GOM47_RS00935 (GOM47_00935) comGG/cglG 172000..172413 (+) 414 WP_235080782.1 competence type IV pilus minor pilin ComGG Machinery gene
  GOM47_RS00940 (GOM47_00940) - 172446..173036 (+) 591 WP_235080783.1 class I SAM-dependent methyltransferase -
  GOM47_RS00945 (GOM47_00945) comYH 173095..174048 (+) 954 WP_235080784.1 class I SAM-dependent methyltransferase Machinery gene
  GOM47_RS00950 (GOM47_00950) - 174098..175288 (+) 1191 WP_235080785.1 acetate kinase -
  GOM47_RS00955 (GOM47_00955) rnpA 175448..175819 (+) 372 WP_000748124.1 ribonuclease P protein component -

Sequence


Protein


Download         Length: 107 a.a.        Molecular weight: 11938.00 Da        Isoelectric Point: 9.6413

>NTDB_id=404963 GOM47_RS00915 WP_235080778.1 170613..170936(+) (comGC/cglC) [Streptococcus oralis strain SOT]
MNKLMTNFKKAKVQAFTLVEMLVVLLIISVLLLLFVPNLTKQKDVVDDKGKAAVVKVVESQAELYSLDKNEDASLSKLQA
DGRITAEQVKAYKDYYAKQKTSQTVAD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=404963 GOM47_RS00915 WP_235080778.1 170613..170936(+) (comGC/cglC) [Streptococcus oralis strain SOT]
ATGAACAAACTCATGACAAATTTTAAAAAAGCCAAGGTTCAAGCTTTCACTCTGGTAGAGATGTTAGTCGTCTTGCTCAT
CATCAGCGTACTCCTCTTGCTCTTTGTGCCCAATTTGACCAAGCAAAAGGATGTTGTTGATGACAAAGGAAAGGCTGCAG
TTGTCAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGTCTGGACAAGAATGAAGATGCTAGCTTAAGTAAATTACAGGCG
GACGGACGTATCACAGCAGAGCAAGTCAAGGCTTATAAAGACTACTATGCGAAACAAAAAACAAGTCAGACTGTTGCAGA
TTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

87.85

100

0.879

  comGC/cglC Streptococcus mitis SK321

87.755

91.589

0.804

  comGC/cglC Streptococcus pneumoniae Rx1

83.673

91.589

0.766

  comGC/cglC Streptococcus pneumoniae D39

83.673

91.589

0.766

  comGC/cglC Streptococcus pneumoniae R6

83.673

91.589

0.766

  comGC/cglC Streptococcus pneumoniae TIGR4

85.263

88.785

0.757

  comYC Streptococcus gordonii str. Challis substr. CH1

65.138

100

0.664

  comYC Streptococcus mutans UA140

69.072

90.654

0.626

  comYC Streptococcus mutans UA159

69.072

90.654

0.626

  comGC Lactococcus lactis subsp. cremoris KW2

58.763

90.654

0.533

  comYC Streptococcus suis isolate S10

62.5

82.243

0.514

  comGC Staphylococcus aureus MW2

51.282

72.897

0.374

  comGC Staphylococcus aureus N315

51.282

72.897

0.374


Multiple sequence alignment