Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   GOM47_RS00925 Genome accession   NZ_CP046524
Coordinates   171296..171598 (+) Length   100 a.a.
NCBI ID   WP_235080780.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOT     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 166296..176598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM47_RS00895 (GOM47_00895) nagA 166974..168125 (+) 1152 WP_001134447.1 N-acetylglucosamine-6-phosphate deacetylase -
  GOM47_RS00900 (GOM47_00900) - 168271..168636 (+) 366 WP_000286396.1 DUF1033 family protein -
  GOM47_RS00905 (GOM47_00905) comGA/cglA/cilD 168706..169647 (+) 942 WP_235080777.1 competence type IV pilus ATPase ComGA Machinery gene
  GOM47_RS00910 (GOM47_00910) comGB/cglB 169595..170611 (+) 1017 WP_235081262.1 competence type IV pilus assembly protein ComGB Machinery gene
  GOM47_RS00915 (GOM47_00915) comGC/cglC 170613..170936 (+) 324 WP_235080778.1 competence type IV pilus major pilin ComGC Machinery gene
  GOM47_RS00920 (GOM47_00920) comGD/cglD 170899..171333 (+) 435 WP_235080779.1 competence type IV pilus minor pilin ComGD Machinery gene
  GOM47_RS00925 (GOM47_00925) comGE/cglE 171296..171598 (+) 303 WP_235080780.1 competence type IV pilus minor pilin ComGE Machinery gene
  GOM47_RS00930 (GOM47_00930) comGF/cglF 171561..172022 (+) 462 WP_235080781.1 competence type IV pilus minor pilin ComGF Machinery gene
  GOM47_RS00935 (GOM47_00935) comGG/cglG 172000..172413 (+) 414 WP_235080782.1 competence type IV pilus minor pilin ComGG Machinery gene
  GOM47_RS00940 (GOM47_00940) - 172446..173036 (+) 591 WP_235080783.1 class I SAM-dependent methyltransferase -
  GOM47_RS00945 (GOM47_00945) comYH 173095..174048 (+) 954 WP_235080784.1 class I SAM-dependent methyltransferase Machinery gene
  GOM47_RS00950 (GOM47_00950) - 174098..175288 (+) 1191 WP_235080785.1 acetate kinase -
  GOM47_RS00955 (GOM47_00955) rnpA 175448..175819 (+) 372 WP_000748124.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11139.10 Da        Isoelectric Point: 8.5546

>NTDB_id=404965 GOM47_RS00925 WP_235080780.1 171296..171598(+) (comGE/cglE) [Streptococcus oralis strain SOT]
MEKLNALKKQKIRAVILLEAVVALAVFASIATLLLGQIQKNRQEEAEILQKEEVLRVAKMALQTGQNQVKVNGVEIQVFA
SEKGVEVYHGSEKLLDLKEQ

Nucleotide


Download         Length: 303 bp        

>NTDB_id=404965 GOM47_RS00925 WP_235080780.1 171296..171598(+) (comGE/cglE) [Streptococcus oralis strain SOT]
ATGGAAAAATTAAACGCATTAAAGAAACAAAAAATTAGGGCAGTGATTTTACTAGAAGCAGTAGTAGCTCTGGCCGTATT
TGCCAGTATTGCAACCCTTCTTTTGGGACAAATCCAGAAAAATAGACAAGAAGAGGCAGAAATTTTGCAAAAAGAGGAAG
TCTTACGTGTCGCTAAGATGGCCTTGCAGACGGGACAAAATCAAGTGAAGGTCAACGGAGTTGAGATTCAGGTATTTGCT
AGTGAAAAAGGAGTGGAGGTCTACCATGGTTCAGAGAAGTTGCTCGACCTTAAAGAGCAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-96)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis SK321

89.899

99

0.89
  comGE/cglE Streptococcus pneumoniae Rx1

89.899

99

0.89
  comGE/cglE Streptococcus pneumoniae D39

89.899

99

0.89
  comGE/cglE Streptococcus pneumoniae R6

89.899

99

0.89
  comGE/cglE Streptococcus pneumoniae TIGR4

89.899

99

0.89
  comGE/cglE Streptococcus mitis NCTC 12261

88.889

99

0.88
  comYE Streptococcus mutans UA140

43.478

92

0.4
  comYE Streptococcus mutans UA159

43.478

92

0.4

Multiple sequence alignment