Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   GOM47_RS00905 Genome accession   NZ_CP046524
Coordinates   168706..169647 (+) Length   313 a.a.
NCBI ID   WP_235080777.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOT     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 163706..174647
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM47_RS00885 (GOM47_00885) tgt 163773..164915 (+) 1143 WP_235080775.1 tRNA guanosine(34) transglycosylase Tgt -
  GOM47_RS00890 (GOM47_00890) - 165016..166833 (+) 1818 WP_235080776.1 acyltransferase family protein -
  GOM47_RS00895 (GOM47_00895) nagA 166974..168125 (+) 1152 WP_001134447.1 N-acetylglucosamine-6-phosphate deacetylase -
  GOM47_RS00900 (GOM47_00900) - 168271..168636 (+) 366 WP_000286396.1 DUF1033 family protein -
  GOM47_RS00905 (GOM47_00905) comGA/cglA/cilD 168706..169647 (+) 942 WP_235080777.1 competence type IV pilus ATPase ComGA Machinery gene
  GOM47_RS00910 (GOM47_00910) comGB/cglB 169595..170611 (+) 1017 WP_235081262.1 competence type IV pilus assembly protein ComGB Machinery gene
  GOM47_RS00915 (GOM47_00915) comGC/cglC 170613..170936 (+) 324 WP_235080778.1 competence type IV pilus major pilin ComGC Machinery gene
  GOM47_RS00920 (GOM47_00920) comGD/cglD 170899..171333 (+) 435 WP_235080779.1 competence type IV pilus minor pilin ComGD Machinery gene
  GOM47_RS00925 (GOM47_00925) comGE/cglE 171296..171598 (+) 303 WP_235080780.1 competence type IV pilus minor pilin ComGE Machinery gene
  GOM47_RS00930 (GOM47_00930) comGF/cglF 171561..172022 (+) 462 WP_235080781.1 competence type IV pilus minor pilin ComGF Machinery gene
  GOM47_RS00935 (GOM47_00935) comGG/cglG 172000..172413 (+) 414 WP_235080782.1 competence type IV pilus minor pilin ComGG Machinery gene
  GOM47_RS00940 (GOM47_00940) - 172446..173036 (+) 591 WP_235080783.1 class I SAM-dependent methyltransferase -
  GOM47_RS00945 (GOM47_00945) comYH 173095..174048 (+) 954 WP_235080784.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35588.51 Da        Isoelectric Point: 5.8185

>NTDB_id=404961 GOM47_RS00905 WP_235080777.1 168706..169647(+) (comGA/cglA/cilD) [Streptococcus oralis strain SOT]
MVQEIAQEIIRSARRKGAQDIYFVPKLDAYELHMRVGDERCKIGCYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYQ
YDEKVSSLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIGELGKQYRQRGLYLFAGPVGSGKTTLMHELAKSLFKGQQ
VMSIEDPVEIKQEEMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVTEEELAVVLQGVCYQRLIGGGGIVDFANKDYQEHQPTSWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=404961 GOM47_RS00905 WP_235080777.1 168706..169647(+) (comGA/cglA/cilD) [Streptococcus oralis strain SOT]
ATGGTTCAAGAAATCGCACAAGAGATCATTCGTTCGGCTAGGAGAAAAGGTGCACAAGACATTTATTTTGTTCCTAAATT
AGATGCGTATGAACTCCATATGAGAGTGGGAGACGAAAGATGTAAAATCGGTTGTTATGATTTTGAAAAATTTGCTGCTG
TGATTAGTCATTTCAAGTTTGTAGCTGGGATGAATGTAGGAGAAAAGCGTCGCAGTCAGCTGGGTTCTTGTGATTATCAG
TATGACGAAAAGGTTTCTTCACTGCGTTTGTCCACCGTGGGAGATTATCGGGGACATGAGAGTTTGGTCATTCGTTTGTT
ACACGATGAGGAGCAGGATCTGCATTTCTGGTTTCAGGATATTGGAGAACTGGGCAAGCAATACAGGCAACGGGGTCTCT
ATCTATTTGCAGGTCCCGTCGGAAGTGGCAAGACGACGCTGATGCACGAATTGGCTAAGTCTCTGTTTAAGGGGCAGCAG
GTTATGTCCATCGAAGACCCTGTCGAGATCAAGCAGGAAGAGATGTTGCAGTTGCAGTTGAATGAGGCGATTGGCTTGAC
CTATGAAAATCTAATCAAACTATCCTTGCGTCATCGTCCCGATCTTTTGATTATCGGTGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCCAGTTTGACAGGGGCGACAGTTTTTTCAACCATTCATGCCAAGAGTATCCGAGGTGTTTAT
GAACGTCTTCTGGAGTTGGGTGTGACGGAGGAGGAACTAGCAGTTGTCCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAACAAAGACTATCAAGAACACCAGCCAACTAGCTGGAATGAGCAGATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

96.486

100

0.965
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

94.569

100

0.946
  comGA/cglA/cilD Streptococcus pneumoniae D39

94.569

100

0.946
  comGA/cglA/cilD Streptococcus pneumoniae R6

94.569

100

0.946
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

94.569

100

0.946
  comYA Streptococcus gordonii str. Challis substr. CH1

78.71

99.042

0.78
  comYA Streptococcus mutans UA159

65.595

99.361

0.652
  comYA Streptococcus mutans UA140

65.595

99.361

0.652
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.29

99.042

0.607
  comGA Lactococcus lactis subsp. cremoris KW2

54.487

99.681

0.543
  comGA Latilactobacillus sakei subsp. sakei 23K

43.019

84.665

0.364

Multiple sequence alignment