Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   GOM47_RS00910 Genome accession   NZ_CP046524
Coordinates   169595..170611 (+) Length   338 a.a.
NCBI ID   WP_235081262.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOT     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 164595..175611
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM47_RS00890 (GOM47_00890) - 165016..166833 (+) 1818 WP_235080776.1 acyltransferase family protein -
  GOM47_RS00895 (GOM47_00895) nagA 166974..168125 (+) 1152 WP_001134447.1 N-acetylglucosamine-6-phosphate deacetylase -
  GOM47_RS00900 (GOM47_00900) - 168271..168636 (+) 366 WP_000286396.1 DUF1033 family protein -
  GOM47_RS00905 (GOM47_00905) comGA/cglA/cilD 168706..169647 (+) 942 WP_235080777.1 competence type IV pilus ATPase ComGA Machinery gene
  GOM47_RS00910 (GOM47_00910) comGB/cglB 169595..170611 (+) 1017 WP_235081262.1 competence type IV pilus assembly protein ComGB Machinery gene
  GOM47_RS00915 (GOM47_00915) comGC/cglC 170613..170936 (+) 324 WP_235080778.1 competence type IV pilus major pilin ComGC Machinery gene
  GOM47_RS00920 (GOM47_00920) comGD/cglD 170899..171333 (+) 435 WP_235080779.1 competence type IV pilus minor pilin ComGD Machinery gene
  GOM47_RS00925 (GOM47_00925) comGE/cglE 171296..171598 (+) 303 WP_235080780.1 competence type IV pilus minor pilin ComGE Machinery gene
  GOM47_RS00930 (GOM47_00930) comGF/cglF 171561..172022 (+) 462 WP_235080781.1 competence type IV pilus minor pilin ComGF Machinery gene
  GOM47_RS00935 (GOM47_00935) comGG/cglG 172000..172413 (+) 414 WP_235080782.1 competence type IV pilus minor pilin ComGG Machinery gene
  GOM47_RS00940 (GOM47_00940) - 172446..173036 (+) 591 WP_235080783.1 class I SAM-dependent methyltransferase -
  GOM47_RS00945 (GOM47_00945) comYH 173095..174048 (+) 954 WP_235080784.1 class I SAM-dependent methyltransferase Machinery gene
  GOM47_RS00950 (GOM47_00950) - 174098..175288 (+) 1191 WP_235080785.1 acetate kinase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38429.51 Da        Isoelectric Point: 9.4244

>NTDB_id=404962 GOM47_RS00910 WP_235081262.1 169595..170611(+) (comGB/cglB) [Streptococcus oralis strain SOT]
MDISQVFRLKRKKLATAKQKKIITLFNNLFSSGFHLVEIISFLGRSALLEKDYVTQMHQGLSQGKSFSEMMESLGFSGAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGLVLVCSLSLLLALTFYKRSTKMGVFSMLARIPFLGIFVQTYLTAYYAREWGNMISQGMELTQIFQIMQEQGSQLFKEI
GQDLAQALQNGREFSQTIATYPFFKKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=404962 GOM47_RS00910 WP_235081262.1 169595..170611(+) (comGB/cglB) [Streptococcus oralis strain SOT]
ATGGACATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAAGCAGAAGAAAATCATCACCCTGTTTAA
CAATCTCTTCTCCAGTGGTTTTCATTTGGTGGAAATTATTTCTTTCTTGGGGAGAAGTGCCTTGCTAGAAAAGGACTATG
TGACACAGATGCACCAAGGGCTGTCTCAGGGGAAATCTTTCTCAGAAATGATGGAAAGTTTAGGATTTTCAGGTGCCATT
GTGACTCAGTTATCCCTAGCTGAAGTTCATGGGAATCTTCATCTGAGTTTGGGAAAGATAGAAGAATATTTGGATAATTT
GGCCAAGGTTAAGAAAAAGTTAATCGAAGTGGCGACCTATCCTTTGATTTTGCTGGGATTTCTCTTGTTAATCATGCTGG
GATTGAGAAACTATCTACTACCCCAACTGGACAGTAGCAATATTGCCACCCAAATCATCGGTAATCTGCCACAAATTTTT
CTTGGACTAGTGTTGGTTTGCTCTCTGTCTCTACTTTTAGCTCTCACTTTCTACAAAAGAAGTACCAAGATGGGGGTCTT
CTCGATGTTGGCACGGATTCCCTTTCTTGGAATCTTTGTCCAGACCTATCTGACAGCTTATTACGCGCGTGAATGGGGCA
ATATGATTTCGCAGGGAATGGAGCTGACGCAGATTTTTCAAATCATGCAGGAACAAGGTTCTCAGCTCTTTAAAGAAATC
GGTCAAGATTTGGCTCAAGCCCTGCAAAATGGCCGCGAATTTTCTCAAACCATAGCGACCTATCCTTTCTTTAAAAAGGA
GTTGAGTCTCATCATTGAGTATGGGGAAGTCAAGTCCAAGCTGGGGAGTGAGTTGGAAATCTATGCCGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATCTGGTGCAGCCACTGGTTTTTATCTTTGTGGCCCTGATTATCGTT
TTACTTTATGCGGCAATGCTTATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus mitis SK321

93.787

100

0.938
  comGB/cglB Streptococcus mitis NCTC 12261

92.899

100

0.929
  comGB/cglB Streptococcus pneumoniae Rx1

91.42

100

0.914
  comGB/cglB Streptococcus pneumoniae D39

91.42

100

0.914
  comGB/cglB Streptococcus pneumoniae R6

91.42

100

0.914
  comGB/cglB Streptococcus pneumoniae TIGR4

91.42

100

0.914
  comYB Streptococcus gordonii str. Challis substr. CH1

73.81

99.408

0.734
  comYB Streptococcus mutans UA140

58.934

94.379

0.556
  comYB Streptococcus mutans UA159

58.934

94.379

0.556
  comGB Lactococcus lactis subsp. cremoris KW2

52.071

100

0.521

Multiple sequence alignment