Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   SOR_RS00840 Genome accession   NC_015291
Coordinates   164583..164906 (+) Length   107 a.a.
NCBI ID   WP_000735753.1    Uniprot ID   F2QGL1
Organism   Streptococcus oralis Uo5     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 159583..169906
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOR_RS00820 (SOR_0167) nagA 160943..162094 (+) 1152 WP_001134448.1 N-acetylglucosamine-6-phosphate deacetylase -
  SOR_RS00825 (SOR_0168) - 162247..162612 (+) 366 WP_000286396.1 DUF1033 family protein -
  SOR_RS00830 (SOR_0169) comGA/cglA/cilD 162676..163617 (+) 942 WP_000249588.1 competence type IV pilus ATPase ComGA Machinery gene
  SOR_RS00835 (SOR_0170) comGB/cglB 163565..164581 (+) 1017 WP_000355374.1 competence type IV pilus assembly protein ComGB Machinery gene
  SOR_RS00840 (SOR_0171) comGC/cglC 164583..164906 (+) 324 WP_000735753.1 competence type IV pilus major pilin ComGC Machinery gene
  SOR_RS00845 (SOR_0172) comGD/cglD 164869..165303 (+) 435 WP_001180057.1 competence type IV pilus minor pilin ComGD Machinery gene
  SOR_RS00850 (SOR_0173) comGE/cglE 165266..165568 (+) 303 WP_000413375.1 competence type IV pilus minor pilin ComGE Machinery gene
  SOR_RS00855 (SOR_0174) comGF/cglF 165531..165992 (+) 462 WP_000250703.1 competence type IV pilus minor pilin ComGF Machinery gene
  SOR_RS00860 (SOR_0175) comGG/cglG 165970..166383 (+) 414 WP_000265656.1 competence type IV pilus minor pilin ComGG Machinery gene
  SOR_RS00865 (SOR_0176) - 166416..167006 (+) 591 WP_000679766.1 class I SAM-dependent methyltransferase -
  SOR_RS00870 (SOR_0177) comYH 167065..168018 (+) 954 WP_000345112.1 class I SAM-dependent methyltransferase Machinery gene
  SOR_RS00875 (SOR_0178) - 168069..169259 (+) 1191 WP_000167792.1 acetate kinase -
  SOR_RS00880 (SOR_0179) rnpA 169409..169780 (+) 372 WP_000748120.1 ribonuclease P protein component -

Sequence


Protein


Download         Length: 107 a.a.        Molecular weight: 11931.14 Da        Isoelectric Point: 10.1883

>NTDB_id=40169 SOR_RS00840 WP_000735753.1 164583..164906(+) (comGC/cglC) [Streptococcus oralis Uo5]
MKKLMIKLKKAQLKAFTLVEMLVVLLIISVLLLLFVPNLTKQKDAVDDKGKAAVVKVVESQAELYRLDKNDDASLSKLQA
DGRITAEQAKAYKDYHAKQKTSQTVAD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=40169 SOR_RS00840 WP_000735753.1 164583..164906(+) (comGC/cglC) [Streptococcus oralis Uo5]
ATGAAAAAACTCATGATAAAACTAAAAAAAGCCCAGCTTAAAGCTTTCACTCTGGTAGAAATGTTAGTCGTCTTGCTCAT
CATCAGTGTTCTTCTCTTGCTCTTTGTGCCCAATTTGACCAAGCAAAAGGATGCCGTAGATGATAAAGGAAAAGCTGCTG
TTGTCAAGGTCGTGGAAAGCCAGGCAGAACTCTATCGTTTAGATAAAAATGATGACGCCAGCCTCAGCAAATTACAAGCG
GACGGTCGTATCACAGCTGAGCAAGCCAAAGCTTATAAAGACTACCATGCAAAACAAAAAACAAGTCAAACTGTTGCAGA
TTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB F2QGL1

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

88.785

100

0.888

  comGC/cglC Streptococcus mitis SK321

85.859

92.523

0.794

  comGC/cglC Streptococcus pneumoniae Rx1

83.838

92.523

0.776

  comGC/cglC Streptococcus pneumoniae D39

83.838

92.523

0.776

  comGC/cglC Streptococcus pneumoniae R6

83.838

92.523

0.776

  comGC/cglC Streptococcus pneumoniae TIGR4

82.828

92.523

0.766

  comYC Streptococcus gordonii str. Challis substr. CH1

67.619

98.131

0.664

  comYC Streptococcus mutans UA140

70.103

90.654

0.636

  comYC Streptococcus mutans UA159

70.103

90.654

0.636

  comGC Lactococcus lactis subsp. cremoris KW2

56.863

95.327

0.542

  comYC Streptococcus suis isolate S10

64.773

82.243

0.533

  comGC Staphylococcus aureus MW2

52.564

72.897

0.383

  comGC Staphylococcus aureus N315

52.564

72.897

0.383


Multiple sequence alignment