Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   SOR_RS00835 Genome accession   NC_015291
Coordinates   163565..164581 (+) Length   338 a.a.
NCBI ID   WP_000355374.1    Uniprot ID   -
Organism   Streptococcus oralis Uo5     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 158565..169581
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOR_RS00815 (SOR_0166) - 158985..160802 (+) 1818 WP_001220900.1 acyltransferase family protein -
  SOR_RS00820 (SOR_0167) nagA 160943..162094 (+) 1152 WP_001134448.1 N-acetylglucosamine-6-phosphate deacetylase -
  SOR_RS00825 (SOR_0168) - 162247..162612 (+) 366 WP_000286396.1 DUF1033 family protein -
  SOR_RS00830 (SOR_0169) comGA/cglA/cilD 162676..163617 (+) 942 WP_000249588.1 competence type IV pilus ATPase ComGA Machinery gene
  SOR_RS00835 (SOR_0170) comGB/cglB 163565..164581 (+) 1017 WP_000355374.1 competence type IV pilus assembly protein ComGB Machinery gene
  SOR_RS00840 (SOR_0171) comGC/cglC 164583..164906 (+) 324 WP_000735753.1 competence type IV pilus major pilin ComGC Machinery gene
  SOR_RS00845 (SOR_0172) comGD/cglD 164869..165303 (+) 435 WP_001180057.1 competence type IV pilus minor pilin ComGD Machinery gene
  SOR_RS00850 (SOR_0173) comGE/cglE 165266..165568 (+) 303 WP_000413375.1 competence type IV pilus minor pilin ComGE Machinery gene
  SOR_RS00855 (SOR_0174) comGF/cglF 165531..165992 (+) 462 WP_000250703.1 competence type IV pilus minor pilin ComGF Machinery gene
  SOR_RS00860 (SOR_0175) comGG/cglG 165970..166383 (+) 414 WP_000265656.1 competence type IV pilus minor pilin ComGG Machinery gene
  SOR_RS00865 (SOR_0176) - 166416..167006 (+) 591 WP_000679766.1 class I SAM-dependent methyltransferase -
  SOR_RS00870 (SOR_0177) comYH 167065..168018 (+) 954 WP_000345112.1 class I SAM-dependent methyltransferase Machinery gene
  SOR_RS00875 (SOR_0178) - 168069..169259 (+) 1191 WP_000167792.1 acetate kinase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38461.57 Da        Isoelectric Point: 9.4400

>NTDB_id=40168 SOR_RS00835 WP_000355374.1 163565..164581(+) (comGB/cglB) [Streptococcus oralis Uo5]
MDISQVFRLKRKKLATAKQKKIITLFNNLFSSGFHLVEIISFLGRSALLEKDYVARMHQGLSQGKSFSEMMDSLGFSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGLVLVCSLSLLLALTFYKRSSKMRVFSMLARIPFLGIFVQTYLTAYYAREWGNMISQGMELTQIFQIMQEQGSQLFKEI
GQDLAQALQNGCEFSQTIGTYPFFKKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=40168 SOR_RS00835 WP_000355374.1 163565..164581(+) (comGB/cglB) [Streptococcus oralis Uo5]
ATGGACATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAAGCAGAAGAAAATCATCACCCTGTTTAA
CAACCTCTTTTCCAGTGGCTTTCATTTGGTGGAAATTATTTCTTTTTTGGGCAGAAGTGCCCTGCTGGAAAAGGACTATG
TGGCCCGGATGCACCAAGGCTTGTCTCAGGGGAAATCCTTTTCAGAGATGATGGACAGCTTGGGGTTTTCAAGTGCTATT
GTGACCCAATTATCTCTAGCTGAAGTACATGGAAATCTTCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGACAATCT
GGCCAAGGTCAAGAAAAAATTAATCGAAGTGGCGACCTATCCCCTGATTTTGCTGGGATTTCTCCTGCTAATCATGCTGG
GGTTGAGGAATTATTTGCTGCCTCAACTGGACAGTAGCAATATCGCCACTCAAATCATCGGCAATCTGCCACAAATTTTT
TTGGGACTAGTGTTGGTTTGCTCTCTATCTTTACTTTTAGCTCTCACTTTCTACAAAAGAAGTTCCAAGATGCGGGTCTT
CTCGATGTTAGCACGGATTCCCTTTCTAGGAATCTTTGTCCAGACTTATCTGACGGCTTATTACGCGCGTGAATGGGGCA
ATATGATTTCACAGGGGATGGAGCTGACGCAGATTTTTCAAATCATGCAGGAACAAGGCTCCCAGCTCTTTAAAGAAATC
GGTCAAGATTTGGCTCAAGCCCTGCAAAATGGCTGCGAATTTTCTCAAACTATAGGAACCTATCCTTTCTTTAAAAAGGA
GTTGAGTCTCATCATCGAGTATGGGGAAGTCAAGTCCAAGCTGGGGAGTGAGTTGGAAATCTACGCGGAAAAGACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAACTTAGTACAGCCACTGGTTTTTATCTTTGTGGCTCTGATTATCGTT
TTACTTTATGCGGCAATGCTTATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus mitis SK321

93.195

100

0.932
  comGB/cglB Streptococcus mitis NCTC 12261

93.195

100

0.932
  comGB/cglB Streptococcus pneumoniae Rx1

91.124

100

0.911
  comGB/cglB Streptococcus pneumoniae D39

91.124

100

0.911
  comGB/cglB Streptococcus pneumoniae R6

91.124

100

0.911
  comGB/cglB Streptococcus pneumoniae TIGR4

91.124

100

0.911
  comYB Streptococcus gordonii str. Challis substr. CH1

73.214

99.408

0.728
  comYB Streptococcus mutans UA140

59.248

94.379

0.559
  comYB Streptococcus mutans UA159

59.248

94.379

0.559
  comGB Lactococcus lactis subsp. cremoris KW2

52.071

100

0.521

Multiple sequence alignment