Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   SOR_RS00850 Genome accession   NC_015291
Coordinates   165266..165568 (+) Length   100 a.a.
NCBI ID   WP_000413375.1    Uniprot ID   F2QGL3
Organism   Streptococcus oralis Uo5     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 160266..170568
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOR_RS00820 (SOR_0167) nagA 160943..162094 (+) 1152 WP_001134448.1 N-acetylglucosamine-6-phosphate deacetylase -
  SOR_RS00825 (SOR_0168) - 162247..162612 (+) 366 WP_000286396.1 DUF1033 family protein -
  SOR_RS00830 (SOR_0169) comGA/cglA/cilD 162676..163617 (+) 942 WP_000249588.1 competence type IV pilus ATPase ComGA Machinery gene
  SOR_RS00835 (SOR_0170) comGB/cglB 163565..164581 (+) 1017 WP_000355374.1 competence type IV pilus assembly protein ComGB Machinery gene
  SOR_RS00840 (SOR_0171) comGC/cglC 164583..164906 (+) 324 WP_000735753.1 competence type IV pilus major pilin ComGC Machinery gene
  SOR_RS00845 (SOR_0172) comGD/cglD 164869..165303 (+) 435 WP_001180057.1 competence type IV pilus minor pilin ComGD Machinery gene
  SOR_RS00850 (SOR_0173) comGE/cglE 165266..165568 (+) 303 WP_000413375.1 competence type IV pilus minor pilin ComGE Machinery gene
  SOR_RS00855 (SOR_0174) comGF/cglF 165531..165992 (+) 462 WP_000250703.1 competence type IV pilus minor pilin ComGF Machinery gene
  SOR_RS00860 (SOR_0175) comGG/cglG 165970..166383 (+) 414 WP_000265656.1 competence type IV pilus minor pilin ComGG Machinery gene
  SOR_RS00865 (SOR_0176) - 166416..167006 (+) 591 WP_000679766.1 class I SAM-dependent methyltransferase -
  SOR_RS00870 (SOR_0177) comYH 167065..168018 (+) 954 WP_000345112.1 class I SAM-dependent methyltransferase Machinery gene
  SOR_RS00875 (SOR_0178) - 168069..169259 (+) 1191 WP_000167792.1 acetate kinase -
  SOR_RS00880 (SOR_0179) rnpA 169409..169780 (+) 372 WP_000748120.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11153.08 Da        Isoelectric Point: 7.0157

>NTDB_id=40171 SOR_RS00850 WP_000413375.1 165266..165568(+) (comGE/cglE) [Streptococcus oralis Uo5]
MEKLNALRKQKIKAVILLEAVVALAVFASIATLLLGQIQKNRQEEAEILQKEEVLRVAKMALQTGQNQVNINGVEIQVFA
SEKGLEVYHGSEKLLDLKEQ

Nucleotide


Download         Length: 303 bp        

>NTDB_id=40171 SOR_RS00850 WP_000413375.1 165266..165568(+) (comGE/cglE) [Streptococcus oralis Uo5]
ATGGAAAAATTAAACGCACTAAGGAAACAAAAAATTAAGGCAGTAATCTTACTAGAAGCAGTAGTAGCTTTGGCTGTGTT
TGCCAGCATTGCGACCCTCCTTTTGGGGCAAATTCAGAAAAATAGACAAGAAGAGGCAGAAATCTTGCAAAAGGAAGAAG
TCTTGCGTGTGGCGAAGATGGCTCTGCAAACAGGGCAAAATCAGGTAAACATAAATGGAGTTGAGATTCAGGTATTTGCA
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAGAAATTGCTCGATCTTAAAGAGCAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-96)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F2QGL3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

91.919

99

0.91
  comGE/cglE Streptococcus pneumoniae Rx1

91.919

99

0.91
  comGE/cglE Streptococcus pneumoniae D39

91.919

99

0.91
  comGE/cglE Streptococcus pneumoniae R6

91.919

99

0.91
  comGE/cglE Streptococcus pneumoniae TIGR4

91.919

99

0.91
  comGE/cglE Streptococcus mitis SK321

90.909

99

0.9
  comYE Streptococcus mutans UA140

43.478

92

0.4
  comYE Streptococcus mutans UA159

43.478

92

0.4

Multiple sequence alignment