Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   SOR_RS00830 Genome accession   NC_015291
Coordinates   162676..163617 (+) Length   313 a.a.
NCBI ID   WP_000249588.1    Uniprot ID   -
Organism   Streptococcus oralis Uo5     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 157676..168617
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOR_RS00810 (SOR_0165) tgt 157709..158851 (+) 1143 WP_001285237.1 tRNA guanosine(34) transglycosylase Tgt -
  SOR_RS00815 (SOR_0166) - 158985..160802 (+) 1818 WP_001220900.1 acyltransferase family protein -
  SOR_RS00820 (SOR_0167) nagA 160943..162094 (+) 1152 WP_001134448.1 N-acetylglucosamine-6-phosphate deacetylase -
  SOR_RS00825 (SOR_0168) - 162247..162612 (+) 366 WP_000286396.1 DUF1033 family protein -
  SOR_RS00830 (SOR_0169) comGA/cglA/cilD 162676..163617 (+) 942 WP_000249588.1 competence type IV pilus ATPase ComGA Machinery gene
  SOR_RS00835 (SOR_0170) comGB/cglB 163565..164581 (+) 1017 WP_000355374.1 competence type IV pilus assembly protein ComGB Machinery gene
  SOR_RS00840 (SOR_0171) comGC/cglC 164583..164906 (+) 324 WP_000735753.1 competence type IV pilus major pilin ComGC Machinery gene
  SOR_RS00845 (SOR_0172) comGD/cglD 164869..165303 (+) 435 WP_001180057.1 competence type IV pilus minor pilin ComGD Machinery gene
  SOR_RS00850 (SOR_0173) comGE/cglE 165266..165568 (+) 303 WP_000413375.1 competence type IV pilus minor pilin ComGE Machinery gene
  SOR_RS00855 (SOR_0174) comGF/cglF 165531..165992 (+) 462 WP_000250703.1 competence type IV pilus minor pilin ComGF Machinery gene
  SOR_RS00860 (SOR_0175) comGG/cglG 165970..166383 (+) 414 WP_000265656.1 competence type IV pilus minor pilin ComGG Machinery gene
  SOR_RS00865 (SOR_0176) - 166416..167006 (+) 591 WP_000679766.1 class I SAM-dependent methyltransferase -
  SOR_RS00870 (SOR_0177) comYH 167065..168018 (+) 954 WP_000345112.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35448.38 Da        Isoelectric Point: 5.4169

>NTDB_id=40167 SOR_RS00830 WP_000249588.1 162676..163617(+) (comGA/cglA/cilD) [Streptococcus oralis Uo5]
MVQEIAQKIIATAKEKKAQDIYFIPKEKSYELHMRVGDERCLVDSYEFDVLAAVISHFKFVAGMNVGEKRRSQLGSCDYQ
HGEKVSSLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDMNELGEQYRQRGLYLFAGPVGSGKTTLMHELAKSLFMGQQ
VMSIEDPVEIKQEDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVTEEELAVVLQGVCYQRLIGGGGIVDFANKDFQEHQPTSWNAQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=40167 SOR_RS00830 WP_000249588.1 162676..163617(+) (comGA/cglA/cilD) [Streptococcus oralis Uo5]
ATGGTACAAGAAATTGCACAGAAAATTATTGCTACTGCGAAAGAAAAGAAGGCCCAGGATATCTATTTTATCCCCAAGGA
AAAGTCCTACGAGCTTCACATGCGGGTTGGAGACGAGCGGTGTCTCGTTGACTCCTATGAGTTTGATGTTTTAGCTGCTG
TGATTAGTCATTTTAAGTTTGTGGCGGGTATGAACGTAGGAGAGAAGAGACGTAGTCAGCTGGGCTCTTGCGACTATCAG
CATGGGGAGAAGGTGTCTTCTCTGCGTTTGTCTACCGTGGGAGATTATCGGGGGCATGAGAGTTTGGTCATTCGTTTGTT
GCACGATGAGGAGCAGGACCTGCATTTCTGGTTTCAGGATATGAACGAACTGGGTGAGCAGTACAGGCAACGGGGACTCT
ATCTCTTTGCAGGTCCAGTCGGAAGTGGCAAGACGACTCTGATGCACGAATTAGCCAAGTCTCTGTTTATGGGGCAACAG
GTCATGTCCATTGAAGATCCTGTCGAGATCAAGCAGGAAGACATGCTCCAGTTGCAGTTGAATGAAGCGATTGGTTTGAC
CTATGAAAATCTCATCAAACTGTCTCTCCGGCATCGTCCTGACCTCTTGATTATCGGTGAAATTCGGGATAGCGAGACGG
CGCGTGCGGTGGTCAGAGCCAGTTTGACAGGGGCGACAGTCTTTTCAACCATTCATGCCAAGAGTATCCGAGGTGTTTAT
GAACGCCTTCTGGAGTTAGGTGTGACGGAGGAAGAATTAGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAACAAAGACTTTCAAGAACACCAGCCAACTAGCTGGAATGCGCAGATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

89.457

100

0.895
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

87.859

100

0.879
  comGA/cglA/cilD Streptococcus pneumoniae D39

87.859

100

0.879
  comGA/cglA/cilD Streptococcus pneumoniae R6

87.859

100

0.879
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

87.859

100

0.879
  comYA Streptococcus gordonii str. Challis substr. CH1

77.742

99.042

0.77
  comYA Streptococcus mutans UA159

66.238

99.361

0.658
  comYA Streptococcus mutans UA140

66.238

99.361

0.658
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.645

99.042

0.601
  comGA Lactococcus lactis subsp. cremoris KW2

55.128

99.681

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

44.061

83.387

0.367

Multiple sequence alignment