Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   SMI_RS01075 Genome accession   NC_013853
Coordinates   207491..207814 (+) Length   107 a.a.
NCBI ID   WP_000738641.1    Uniprot ID   -
Organism   Streptococcus mitis B6     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 202491..212814
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMI_RS01050 (smi_0202) nagA 202683..203834 (+) 1152 WP_001134545.1 N-acetylglucosamine-6-phosphate deacetylase -
  SMI_RS01055 (smi_0203) - 203998..205056 (+) 1059 WP_000649461.1 zinc-dependent alcohol dehydrogenase family protein -
  SMI_RS01060 (smi_0204) - 205142..205507 (+) 366 WP_000286392.1 DUF1033 family protein -
  SMI_RS01065 (smi_0205) comGA/cglA/cilD 205584..206525 (+) 942 WP_000249543.1 competence type IV pilus ATPase ComGA Machinery gene
  SMI_RS01070 (smi_0206) comGB/cglB 206473..207489 (+) 1017 WP_164925538.1 competence type IV pilus assembly protein ComGB Machinery gene
  SMI_RS01075 (smi_0207) comGC/cglC 207491..207814 (+) 324 WP_000738641.1 comG operon protein ComGC Machinery gene
  SMI_RS01080 (smi_0208) comGD/cglD 207777..208211 (+) 435 WP_164925504.1 competence type IV pilus minor pilin ComGD Machinery gene
  SMI_RS01085 (smi_0209) comGE/cglE 208174..208476 (+) 303 WP_153197443.1 competence type IV pilus minor pilin ComGE Machinery gene
  SMI_RS01090 (smi_0210) comGF/cglF 208439..208900 (+) 462 WP_000250522.1 competence type IV pilus minor pilin ComGF Machinery gene
  SMI_RS01095 (smi_0211) comGG/cglG 208878..209291 (+) 414 WP_000265641.1 competence type IV pilus minor pilin ComGG Machinery gene
  SMI_RS01100 (smi_0212) - 209324..209909 (+) 586 Protein_201 class I SAM-dependent methyltransferase -
  SMI_RS01105 (smi_0213) comYH 209970..210923 (+) 954 WP_000345096.1 class I SAM-dependent methyltransferase Machinery gene
  SMI_RS01110 (smi_0214) - 211034..212167 (+) 1134 WP_001113734.1 acetate kinase -
  SMI_RS01115 (smi_0215) rnpA 212313..212684 (+) 372 WP_000739250.1 ribonuclease P protein component -

Sequence


Protein


Download         Length: 107 a.a.        Molecular weight: 11958.09 Da        Isoelectric Point: 9.9097

>NTDB_id=36285 SMI_RS01075 WP_000738641.1 207491..207814(+) (comGC/cglC) [Streptococcus mitis B6]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLDKNEDASLSKLQA
DGRITEEQAKAYKEYHAKQNTSQTVAD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=36285 SMI_RS01075 WP_000738641.1 207491..207814(+) (comGC/cglC) [Streptococcus mitis B6]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCGAAAGTGAAGGCTTTCACACTTGTGGAAATGTTGGTGGTCTTGCTCAT
CATCAGCGTGCTTCTCTTGCTCTTTGTACCTAATTTGACCAAGCAAAAAGAGGCGGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTAGTGGAAAGCCAGGCAGAACTTTATAGCTTAGATAAAAATGAAGATGCTAGCCTAAGCAAGTTACAAGCA
GATGGGCGAATCACAGAAGAACAGGCTAAAGCCTATAAAGAATACCATGCTAAACAAAATACCAGTCAAACCGTTGCAGA
TTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

100

100

1

  comGC/cglC Streptococcus mitis SK321

93.204

96.262

0.897

  comGC/cglC Streptococcus pneumoniae Rx1

92.157

95.327

0.879

  comGC/cglC Streptococcus pneumoniae D39

92.157

95.327

0.879

  comGC/cglC Streptococcus pneumoniae R6

92.157

95.327

0.879

  comGC/cglC Streptococcus pneumoniae TIGR4

90.291

96.262

0.869

  comYC Streptococcus gordonii str. Challis substr. CH1

69.524

98.131

0.682

  comYC Streptococcus mutans UA140

68.421

88.785

0.607

  comYC Streptococcus mutans UA159

68.421

88.785

0.607

  comYC Streptococcus suis isolate S10

70.37

75.701

0.533

  comGC Lactococcus lactis subsp. cremoris KW2

54.455

94.393

0.514

  comGC Staphylococcus aureus MW2

51.163

80.374

0.411

  comGC Staphylococcus aureus N315

51.163

80.374

0.411


Multiple sequence alignment