Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGG/cglG   Type   Machinery gene
Locus tag   SMI_RS01095 Genome accession   NC_013853
Coordinates   208878..209291 (+) Length   137 a.a.
NCBI ID   WP_000265641.1    Uniprot ID   D3H6K4
Organism   Streptococcus mitis B6     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 203878..214291
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMI_RS01055 (smi_0203) - 203998..205056 (+) 1059 WP_000649461.1 zinc-dependent alcohol dehydrogenase family protein -
  SMI_RS01060 (smi_0204) - 205142..205507 (+) 366 WP_000286392.1 DUF1033 family protein -
  SMI_RS01065 (smi_0205) comGA/cglA/cilD 205584..206525 (+) 942 WP_000249543.1 competence type IV pilus ATPase ComGA Machinery gene
  SMI_RS01070 (smi_0206) comGB/cglB 206473..207489 (+) 1017 WP_164925538.1 competence type IV pilus assembly protein ComGB Machinery gene
  SMI_RS01075 (smi_0207) comGC/cglC 207491..207814 (+) 324 WP_000738641.1 comG operon protein ComGC Machinery gene
  SMI_RS01080 (smi_0208) comGD/cglD 207777..208211 (+) 435 WP_164925504.1 competence type IV pilus minor pilin ComGD Machinery gene
  SMI_RS01085 (smi_0209) comGE/cglE 208174..208476 (+) 303 WP_153197443.1 competence type IV pilus minor pilin ComGE Machinery gene
  SMI_RS01090 (smi_0210) comGF/cglF 208439..208900 (+) 462 WP_000250522.1 competence type IV pilus minor pilin ComGF Machinery gene
  SMI_RS01095 (smi_0211) comGG/cglG 208878..209291 (+) 414 WP_000265641.1 competence type IV pilus minor pilin ComGG Machinery gene
  SMI_RS01100 (smi_0212) - 209324..209909 (+) 586 Protein_201 class I SAM-dependent methyltransferase -
  SMI_RS01105 (smi_0213) comYH 209970..210923 (+) 954 WP_000345096.1 class I SAM-dependent methyltransferase Machinery gene
  SMI_RS01110 (smi_0214) - 211034..212167 (+) 1134 WP_001113734.1 acetate kinase -
  SMI_RS01115 (smi_0215) rnpA 212313..212684 (+) 372 WP_000739250.1 ribonuclease P protein component -
  SMI_RS01120 (smi_0216) - 212659..213483 (+) 825 WP_219335883.1 membrane protein insertase YidC -

Sequence


Protein


Download         Length: 137 a.a.        Molecular weight: 15889.42 Da        Isoelectric Point: 10.3716

>NTDB_id=36289 SMI_RS01095 WP_000265641.1 208878..209291(+) (comGG/cglG) [Streptococcus mitis B6]
MWKKQKVKAGVLIYAVTMAATFSLLLQFYLNRQAAHYQDYALNKEKLVAFAMAKRTKDKVDKESGEQIFNLGQVSYQNKK
TSLVTRVRTPKSQYEFLFPSVKIKEEKTDKKEKVATDLSEKAEKKKSEEKVEKKENS

Nucleotide


Download         Length: 414 bp        

>NTDB_id=36289 SMI_RS01095 WP_000265641.1 208878..209291(+) (comGG/cglG) [Streptococcus mitis B6]
GTGTGGAAAAAGCAAAAAGTTAAGGCGGGTGTTCTCATCTATGCAGTCACTATGGCAGCCACCTTTAGTCTTTTGTTACA
ATTTTACTTGAACAGACAAGCTGCCCACTATCAAGACTATGCTTTGAATAAAGAAAAGTTGGTTGCTTTTGCCATGGCCA
AGCGAACCAAAGATAAGGTTGATAAGGAAAGTGGGGAACAGATCTTTAATCTGGGTCAGGTGAGTTATCAAAACAAGAAA
ACAAGCTTGGTGACAAGGGTTCGTACGCCTAAGAGTCAATATGAGTTTCTGTTTCCTTCCGTCAAAATCAAAGAAGAGAA
AACAGATAAAAAGGAAAAGGTAGCGACTGATTTAAGCGAAAAAGCAGAGAAGAAAAAATCAGAAGAGAAGGTTGAAAAGA
AAGAGAATTCCTAG

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB D3H6K4

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGG/cglG Streptococcus mitis SK321

89.051

100

0.891

  comGG/cglG Streptococcus mitis NCTC 12261

89.344

89.051

0.796

  comGG/cglG Streptococcus pneumoniae Rx1

89.744

85.401

0.766

  comGG/cglG Streptococcus pneumoniae D39

89.744

85.401

0.766

  comGG/cglG Streptococcus pneumoniae R6

89.744

85.401

0.766

  comGG/cglG Streptococcus pneumoniae TIGR4

89.744

85.401

0.766


Multiple sequence alignment