Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   SMI_RS01085 Genome accession   NC_013853
Coordinates   208174..208476 (+) Length   100 a.a.
NCBI ID   WP_153197443.1    Uniprot ID   -
Organism   Streptococcus mitis B6     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 203174..213476
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMI_RS01055 (smi_0203) - 203998..205056 (+) 1059 WP_000649461.1 zinc-dependent alcohol dehydrogenase family protein -
  SMI_RS01060 (smi_0204) - 205142..205507 (+) 366 WP_000286392.1 DUF1033 family protein -
  SMI_RS01065 (smi_0205) comGA/cglA/cilD 205584..206525 (+) 942 WP_000249543.1 competence type IV pilus ATPase ComGA Machinery gene
  SMI_RS01070 (smi_0206) comGB/cglB 206473..207489 (+) 1017 WP_164925538.1 competence type IV pilus assembly protein ComGB Machinery gene
  SMI_RS01075 (smi_0207) comGC/cglC 207491..207814 (+) 324 WP_000738641.1 comG operon protein ComGC Machinery gene
  SMI_RS01080 (smi_0208) comGD/cglD 207777..208211 (+) 435 WP_164925504.1 competence type IV pilus minor pilin ComGD Machinery gene
  SMI_RS01085 (smi_0209) comGE/cglE 208174..208476 (+) 303 WP_153197443.1 competence type IV pilus minor pilin ComGE Machinery gene
  SMI_RS01090 (smi_0210) comGF/cglF 208439..208900 (+) 462 WP_000250522.1 competence type IV pilus minor pilin ComGF Machinery gene
  SMI_RS01095 (smi_0211) comGG/cglG 208878..209291 (+) 414 WP_000265641.1 competence type IV pilus minor pilin ComGG Machinery gene
  SMI_RS01100 (smi_0212) - 209324..209909 (+) 586 Protein_201 class I SAM-dependent methyltransferase -
  SMI_RS01105 (smi_0213) comYH 209970..210923 (+) 954 WP_000345096.1 class I SAM-dependent methyltransferase Machinery gene
  SMI_RS01110 (smi_0214) - 211034..212167 (+) 1134 WP_001113734.1 acetate kinase -
  SMI_RS01115 (smi_0215) rnpA 212313..212684 (+) 372 WP_000739250.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11149.18 Da        Isoelectric Point: 10.0522

>NTDB_id=36287 SMI_RS01085 WP_153197443.1 208174..208476(+) (comGE/cglE) [Streptococcus mitis B6]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVKINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=36287 SMI_RS01085 WP_153197443.1 208174..208476(+) (comGE/cglE) [Streptococcus mitis B6]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGTATTGCTACCCTTCTTTTGGGACAAATTCAAAAGAATAGGCAAGAAGAAGCAAAAATTTTGCAAAAGGAAGAAG
TCTTGCGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAAGATCAACGGAGTGGAGATTCAGGTGTTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis SK321

99

100

0.99
  comGE/cglE Streptococcus pneumoniae Rx1

99

100

0.99
  comGE/cglE Streptococcus pneumoniae D39

99

100

0.99
  comGE/cglE Streptococcus pneumoniae R6

99

100

0.99
  comGE/cglE Streptococcus pneumoniae TIGR4

99

100

0.99
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comYE Streptococcus mutans UA140

43.333

90

0.39
  comYE Streptococcus mutans UA159

43.333

90

0.39

Multiple sequence alignment