Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   SP70585_RS10625 Genome accession   NC_012468
Coordinates   1958777..1959100 (-) Length   107 a.a.
NCBI ID   WP_000738628.1    Uniprot ID   -
Organism   Streptococcus pneumoniae 70585     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1953777..1964100
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP70585_RS10585 (SP70585_2131) comYH 1953917..1954870 (-) 954 WP_000345132.1 class I SAM-dependent methyltransferase Machinery gene
  SP70585_RS12905 - 1955216..1956018 (+) 803 Protein_1995 IS5 family transposase -
  SP70585_RS10600 (SP70585_2134) - 1956169..1956645 (+) 477 WP_000777686.1 GNAT family N-acetyltransferase -
  SP70585_RS10605 (SP70585_2135) comGG/cglG 1957300..1957713 (-) 414 WP_000265615.1 competence type IV pilus minor pilin ComGG Machinery gene
  SP70585_RS10610 (SP70585_2136) comGF/cglF 1957691..1958152 (-) 462 WP_000250520.1 competence type IV pilus minor pilin ComGF Machinery gene
  SP70585_RS10615 (SP70585_2137) comGE/cglE 1958115..1958417 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  SP70585_RS10620 (SP70585_2138) comGD/cglD 1958380..1958814 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  SP70585_RS10625 (SP70585_2139) comGC/cglC 1958777..1959100 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  SP70585_RS10630 (SP70585_2140) comGB/cglB 1959102..1960118 (-) 1017 WP_078141518.1 competence type IV pilus assembly protein ComGB Machinery gene
  SP70585_RS10635 (SP70585_2141) comGA/cglA/cilD 1960066..1961007 (-) 942 WP_000249572.1 competence type IV pilus ATPase ComGA Machinery gene
  SP70585_RS10640 (SP70585_2142) - 1961083..1961448 (-) 366 WP_000286415.1 DUF1033 family protein -
  SP70585_RS10645 (SP70585_2143) - 1961599..1962657 (-) 1059 WP_000649465.1 zinc-dependent alcohol dehydrogenase family protein -
  SP70585_RS10650 (SP70585_2144) nagA 1962820..1963971 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 107 a.a.        Molecular weight: 12232.41 Da        Isoelectric Point: 9.8887

>NTDB_id=33342 SP70585_RS10625 WP_000738628.1 1958777..1959100(-) (comGC/cglC) [Streptococcus pneumoniae 70585]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQD
DGRITEEQAKAYKEYHDKQNTSQIVKD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=33342 SP70585_RS10625 WP_000738628.1 1958777..1959100(-) (comGC/cglC) [Streptococcus pneumoniae 70585]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGAC
GATGGACGCATCACGGAAGAACAGGCTAAAGCCTATAAAGAATACCATGATAAACAAAATACTAGTCAAATCGTTAAAGA
TTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

93.458

100

0.935
  comGC/cglC Streptococcus pneumoniae D39

94.175

96.262

0.907
  comGC/cglC Streptococcus pneumoniae R6

94.175

96.262

0.907
  comGC/cglC Streptococcus pneumoniae Rx1

94.175

96.262

0.907
  comGC/cglC Streptococcus pneumoniae TIGR4

93.204

96.262

0.897
  comGC/cglC Streptococcus mitis SK321

88.35

96.262

0.85
  comYC Streptococcus gordonii str. Challis substr. CH1

69.388

91.589

0.636
  comYC Streptococcus mutans UA140

64.211

88.785

0.57
  comYC Streptococcus mutans UA159

64.211

88.785

0.57
  comYC Streptococcus suis isolate S10

69.136

75.701

0.523
  comGC Lactococcus lactis subsp. cremoris KW2

54.639

90.654

0.495
  comGC Staphylococcus aureus MW2

48.837

80.374

0.393
  comGC Staphylococcus aureus N315

48.837

80.374

0.393
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

80.374

0.364

Multiple sequence alignment