Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   SP70585_RS10635 Genome accession   NC_012468
Coordinates   1960066..1961007 (-) Length   313 a.a.
NCBI ID   WP_000249572.1    Uniprot ID   -
Organism   Streptococcus pneumoniae 70585     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1955066..1966007
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP70585_RS12905 - 1955216..1956018 (+) 803 Protein_1995 IS5 family transposase -
  SP70585_RS10600 (SP70585_2134) - 1956169..1956645 (+) 477 WP_000777686.1 GNAT family N-acetyltransferase -
  SP70585_RS10605 (SP70585_2135) comGG/cglG 1957300..1957713 (-) 414 WP_000265615.1 competence type IV pilus minor pilin ComGG Machinery gene
  SP70585_RS10610 (SP70585_2136) comGF/cglF 1957691..1958152 (-) 462 WP_000250520.1 competence type IV pilus minor pilin ComGF Machinery gene
  SP70585_RS10615 (SP70585_2137) comGE/cglE 1958115..1958417 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  SP70585_RS10620 (SP70585_2138) comGD/cglD 1958380..1958814 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  SP70585_RS10625 (SP70585_2139) comGC/cglC 1958777..1959100 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  SP70585_RS10630 (SP70585_2140) comGB/cglB 1959102..1960118 (-) 1017 WP_078141518.1 competence type IV pilus assembly protein ComGB Machinery gene
  SP70585_RS10635 (SP70585_2141) comGA/cglA/cilD 1960066..1961007 (-) 942 WP_000249572.1 competence type IV pilus ATPase ComGA Machinery gene
  SP70585_RS10640 (SP70585_2142) - 1961083..1961448 (-) 366 WP_000286415.1 DUF1033 family protein -
  SP70585_RS10645 (SP70585_2143) - 1961599..1962657 (-) 1059 WP_000649465.1 zinc-dependent alcohol dehydrogenase family protein -
  SP70585_RS10650 (SP70585_2144) nagA 1962820..1963971 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  SP70585_RS10655 (SP70585_2145) - 1964124..1965941 (-) 1818 WP_001220923.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35619.57 Da        Isoelectric Point: 6.0083

>NTDB_id=33344 SP70585_RS10635 WP_000249572.1 1960066..1961007(-) (comGA/cglA/cilD) [Streptococcus pneumoniae 70585]
MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKMASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFANRDYQEHQAVKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=33344 SP70585_RS10635 WP_000249572.1 1960066..1961007(-) (comGA/cglA/cilD) [Streptococcus pneumoniae 70585]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCAGCTCGGAAAAAAGGGACGCAGGATATTTATTTTGTCCCTAAGTT
AGATGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATGGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACTTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAACAGAGATTATCAAGAACACCAAGCAGTCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

98.722

100

0.987
  comGA/cglA/cilD Streptococcus pneumoniae D39

98.722

100

0.987
  comGA/cglA/cilD Streptococcus pneumoniae R6

98.722

100

0.987
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

98.722

100

0.987
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

96.805

100

0.968
  comYA Streptococcus gordonii str. Challis substr. CH1

77.742

99.042

0.77
  comYA Streptococcus mutans UA159

65.916

99.361

0.655
  comYA Streptococcus mutans UA140

65.916

99.361

0.655
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.581

99.042

0.62
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

99.681

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

42.642

84.665

0.361

Multiple sequence alignment