Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   SP70585_RS10630 Genome accession   NC_012468
Coordinates   1959102..1960118 (-) Length   338 a.a.
NCBI ID   WP_078141518.1    Uniprot ID   -
Organism   Streptococcus pneumoniae 70585     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1954102..1965118
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP70585_RS12905 - 1955216..1956018 (+) 803 Protein_1995 IS5 family transposase -
  SP70585_RS10600 (SP70585_2134) - 1956169..1956645 (+) 477 WP_000777686.1 GNAT family N-acetyltransferase -
  SP70585_RS10605 (SP70585_2135) comGG/cglG 1957300..1957713 (-) 414 WP_000265615.1 competence type IV pilus minor pilin ComGG Machinery gene
  SP70585_RS10610 (SP70585_2136) comGF/cglF 1957691..1958152 (-) 462 WP_000250520.1 competence type IV pilus minor pilin ComGF Machinery gene
  SP70585_RS10615 (SP70585_2137) comGE/cglE 1958115..1958417 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  SP70585_RS10620 (SP70585_2138) comGD/cglD 1958380..1958814 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  SP70585_RS10625 (SP70585_2139) comGC/cglC 1958777..1959100 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  SP70585_RS10630 (SP70585_2140) comGB/cglB 1959102..1960118 (-) 1017 WP_078141518.1 competence type IV pilus assembly protein ComGB Machinery gene
  SP70585_RS10635 (SP70585_2141) comGA/cglA/cilD 1960066..1961007 (-) 942 WP_000249572.1 competence type IV pilus ATPase ComGA Machinery gene
  SP70585_RS10640 (SP70585_2142) - 1961083..1961448 (-) 366 WP_000286415.1 DUF1033 family protein -
  SP70585_RS10645 (SP70585_2143) - 1961599..1962657 (-) 1059 WP_000649465.1 zinc-dependent alcohol dehydrogenase family protein -
  SP70585_RS10650 (SP70585_2144) nagA 1962820..1963971 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38586.68 Da        Isoelectric Point: 9.7316

>NTDB_id=33343 SP70585_RS10630 WP_078141518.1 1959102..1960118(-) (comGB/cglB) [Streptococcus pneumoniae 70585]
MDISQVFRLRRKKLATAKQKNIITLFNNFFSSGFHLVETISFLDRSALLDKQCVTRMRVGLSQGKSFSEMMESLGCSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=33343 SP70585_RS10630 WP_078141518.1 1959102..1960118(-) (comGB/cglB) [Streptococcus pneumoniae 70585]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATTTCTTTTCTAGCGGTTTTCATCTGGTGGAGACCATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGACCCGGATGCGTGTGGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTGCTATT
GTCACTCAGTTATCCCTAGCTGAAGTTCATGGCAATCTCCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGACAATCT
GGCCAAGGTCAAGAAAAAATTGATTGAAGTAGCGACCTATCCCTTGATTTTGCTGTTTTTTCTTCTCTTAATCATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATATTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATTTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(28-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.521

100

0.985
  comGB/cglB Streptococcus pneumoniae D39

98.521

100

0.985
  comGB/cglB Streptococcus pneumoniae R6

98.521

100

0.985
  comGB/cglB Streptococcus pneumoniae TIGR4

98.521

100

0.985
  comGB/cglB Streptococcus mitis SK321

94.379

100

0.944
  comGB/cglB Streptococcus mitis NCTC 12261

93.787

100

0.938
  comYB Streptococcus gordonii str. Challis substr. CH1

70.238

99.408

0.698
  comYB Streptococcus mutans UA140

57.862

94.083

0.544
  comYB Streptococcus mutans UA159

57.862

94.083

0.544
  comGB Lactococcus lactis subsp. cremoris KW2

50.599

98.817

0.5

Multiple sequence alignment