Detailed information NTG0033337

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: SP70585_RS10585
• Genome accession: NC_012468
• Coordinates: 1953917..1954870 (-)
• Length: 317 a.a.
• NCBI ID: WP_000345132.1
• Uniprot ID: A0A4J2GMF8
• Organism: Streptococcus pneumoniae 70585
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1955294..1955914	1953917..1954870	flank	424

Gene organization within MGE regions

Location: 1953917..1955914

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP70585_RS10585 (SP70585_2131)	comYH	1953917..1954870 (-)	954	WP_000345132.1	class I SAM-dependent methyltransferase	Machinery gene

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 35661.78 Da
• Isoelectric Point: 4.1925

>NTDB_id=33337 SP70585_RS10585 WP_000345132.1 1953917..1954870(-) (comYH) [Streptococcus pneumoniae 70585]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFTEEEITILEMGSGMGILGATFLTSLAKKVDYLGMEMDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANANQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide

• Length: 954 bp

>NTDB_id=33337 SP70585_RS10585 WP_000345132.1 1953917..1954870(-) (comYH) [Streptococcus pneumoniae 70585]
ATGGATTTTGAAAAAATTGAACAAGCCTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGACAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACGCCAGATGCTATTGCCTTACTTTTGGTATTTATTGTGGAAGAGTTGTTTAC
AGAGGAGGAAATCACTATCCTTGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTAACCTCGCTTGCTAAAA
AAGTGGATTACTTGGGAATGGAAATGGATGATTTGCTGATTGATTTGGCAGCTAGTATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAACCAATCTAAGACTATTTTTATCCTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (69-282)

3D structure

• AlphaFold DB: A0A4J2GMF8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA140	54.313	98.738	0.536
comYH	Streptococcus mutans UA159	53.994	98.738	0.533