Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   EXA24_RS10040 Genome accession   NZ_CP036376
Coordinates   1970178..1971512 (-) Length   444 a.a.
NCBI ID   WP_001089363.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain Sag153     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1965178..1976512
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA24_RS10000 (EXA24_10345) - 1965454..1965879 (-) 426 WP_000823120.1 PTS mannose transporter subunit IIA -
  EXA24_RS10005 (EXA24_10350) - 1966126..1967160 (-) 1035 WP_000369171.1 acyltransferase family protein -
  EXA24_RS10010 (EXA24_10355) - 1967212..1967394 (+) 183 WP_001866975.1 hypothetical protein -
  EXA24_RS10015 (EXA24_10360) - 1967389..1968541 (-) 1153 Protein_1898 ABC transporter permease subunit -
  EXA24_RS10025 (EXA24_10370) - 1968547..1969394 (-) 848 Protein_1899 ABC transporter ATP-binding protein -
  EXA24_RS10030 (EXA24_10375) - 1969463..1969636 (-) 174 WP_000683598.1 hypothetical protein -
  EXA24_RS10035 (EXA24_10380) - 1969925..1970089 (+) 165 Protein_1901 cysteine peptidase family C39 domain-containing protein -
  EXA24_RS10040 (EXA24_10385) comD/blpH 1970178..1971512 (-) 1335 WP_001089363.1 GHKL domain-containing protein Regulator
  EXA24_RS10045 (EXA24_10390) - 1971509..1972261 (-) 753 Protein_1903 response regulator transcription factor -
  EXA24_RS10050 (EXA24_10400) - 1972477..1973292 (-) 816 WP_001029870.1 endonuclease/exonuclease/phosphatase family protein -
  EXA24_RS10055 (EXA24_10405) - 1973346..1975529 (-) 2184 WP_000795065.1 PTS transporter subunit IIBC -

Sequence

Protein


Download         Length: 444 a.a.        Molecular weight: 51233.02 Da        Isoelectric Point: 8.5194

>NTDB_id=307055 EXA24_RS10040 WP_001089363.1 1970178..1971512(-) (comD/blpH) [Streptococcus agalactiae strain Sag153]
MNSTLSILEIALTIILTIFLFSKISGRQLTLIEIGICIALRLGLVILFIAANTIINLSFLKYWLLPIYMLSLAFLLLRPI
SKTLVVFYGLFPIVLRNLCSRSLAFFVFPLFNIDFHTTNQGFWGYFVDVLSTLCVLLFLRWMQYDFKALRSSEVSPTDRR
ILQFTNGCMVSYYLLMQFLTYFEYELAINTVIYRQFLLVAYWIIFTGAIASLDRRLRNSLQERLAVQRELQLANMIDYSH
HIEGLYKEVRSFRHDYSNMLTTLKLGIDNEDISIVKSVYQSIFKESNTHFRHPKYNIDRLVNVDNPALKSLLAAKLSQAI
ANHIMVSIEVPDSIKPQGMELIDFITIVSVLWDNAIEASLETDDPKIAMSYFTLKHKQIFIIENSTKEKAIDTSTIFNYE
ISSKGRNRGIGLYNVRGVINRYPNISIATSSQDFSFCQTFEIIL

Nucleotide


Download         Length: 1335 bp        

>NTDB_id=307055 EXA24_RS10040 WP_001089363.1 1970178..1971512(-) (comD/blpH) [Streptococcus agalactiae strain Sag153]
ATGAATTCTACTCTATCCATCTTAGAGATAGCTTTAACGATAATATTAACAATATTTCTCTTTTCTAAAATCAGTGGACG
TCAATTAACTTTAATAGAGATTGGAATTTGTATTGCTCTGAGATTAGGACTTGTAATTTTATTTATAGCAGCTAATACTA
TTATTAATCTTTCATTTCTAAAGTACTGGCTTCTCCCCATCTATATGTTAAGTCTGGCTTTCTTGTTGCTAAGACCTATA
TCTAAAACTTTAGTAGTCTTTTATGGCTTGTTTCCAATTGTTCTCAGAAATCTTTGTTCACGTTCTTTAGCTTTTTTTGT
CTTTCCTTTGTTTAATATTGATTTTCATACAACCAACCAGGGGTTTTGGGGATATTTTGTTGATGTCTTGTCTACTCTTT
GTGTTCTCTTATTTTTAAGATGGATGCAATACGATTTTAAAGCATTGCGAAGTAGTGAAGTTTCGCCAACAGATAGGAGA
ATTCTCCAATTTACGAATGGGTGCATGGTGAGTTATTACTTATTGATGCAGTTTTTAACTTACTTCGAATATGAATTAGC
CATCAATACTGTTATTTACCGACAATTTTTGCTTGTTGCTTATTGGATTATATTTACGGGAGCAATAGCCAGTTTAGACC
GGAGACTTCGAAATTCTTTACAGGAGAGGTTAGCTGTTCAAAGAGAACTCCAATTGGCTAATATGATAGATTATAGCCAC
CATATTGAGGGATTGTATAAAGAAGTTAGGAGCTTCCGACATGATTATAGTAACATGTTAACGACCTTGAAACTAGGGAT
TGATAATGAAGATATATCTATTGTCAAATCAGTTTATCAGTCTATCTTTAAAGAATCTAATACACATTTCCGACATCCTA
AGTATAATATAGACCGGTTGGTTAATGTAGATAACCCAGCCTTAAAAAGTCTTTTAGCAGCCAAGCTTTCACAAGCGATA
GCCAATCATATTATGGTATCTATAGAAGTACCAGACAGTATTAAACCTCAAGGGATGGAACTGATTGATTTTATTACCAT
TGTATCTGTTTTATGGGATAACGCTATTGAGGCATCTTTAGAGACAGACGATCCTAAGATAGCCATGTCTTATTTTACAT
TAAAACATAAACAAATTTTTATCATAGAAAATTCAACTAAGGAAAAGGCAATAGATACGTCAACGATATTCAATTATGAG
ATAAGTAGTAAGGGGCGGAATAGAGGAATAGGTCTTTACAATGTCAGGGGAGTTATCAATCGTTATCCAAATATTTCTAT
TGCAACAAGTAGCCAAGATTTTAGTTTCTGCCAAACTTTCGAAATCATATTATAG

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(339-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

35.683

100

0.365

Multiple sequence alignment