Detailed information NTG0306449

Bioinformatically predicted

Overview

• Name: comA/comEC
• Type: Machinery gene
• Locus tag: DMO12_RS14505
• Genome accession: NZ_CP031380
• Coordinates: 3023447..3025882 (-)
• Length: 811 a.a.
• NCBI ID: WP_000472704.1
• Uniprot ID: A0A7U3Y2A4
• Organism: Acinetobacter baumannii ACICU
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 3018447..3030882

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DMO12_RS14480 (DMO12_08628)	purM	3018770..3019840 (+)	1071	WP_000071984.1	phosphoribosylformylglycinamidine cyclo-ligase	-
DMO12_RS14485 (DMO12_08631)	purN	3019837..3020466 (+)	630	WP_000975536.1	phosphoribosylglycinamide formyltransferase	-
DMO12_RS14490 (DMO12_08634)	-	3020530..3021339 (-)	810	WP_000114076.1	alpha/beta fold hydrolase	-
DMO12_RS14495 (DMO12_08637)	sppA	3021358..3022374 (-)	1017	WP_001286615.1	signal peptide peptidase SppA	-
DMO12_RS14500 (DMO12_08640)	-	3022511..3023494 (+)	984	WP_001984639.1	lysophospholipid acyltransferase family protein	-
DMO12_RS14505 (DMO12_08643)	comA/comEC	3023447..3025882 (-)	2436	WP_000472704.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DMO12_RS14510 (DMO12_08646)	lolD	3025968..3026654 (-)	687	WP_000049403.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
DMO12_RS14515 (DMO12_08649)	-	3026647..3027882 (-)	1236	WP_001984636.1	lipoprotein-releasing ABC transporter permease subunit	-
DMO12_RS14520 (DMO12_08652)	-	3028130..3029038 (-)	909	WP_001140078.1	DMT family transporter	-
DMO12_RS14525 (DMO12_08655)	-	3029049..3029534 (-)	486	WP_001985538.1	YaiI/YqxD family protein	-
DMO12_RS14530 (DMO12_08658)	-	3029791..3030732 (+)	942	WP_000795874.1	hypothetical protein	-

Sequence

Protein

• Length: 811 a.a.
• Molecular weight: 92541.77 Da
• Isoelectric Point: 8.5356

>NTDB_id=306449 DMO12_RS14505 WP_000472704.1 3023447..3025882(-) (comA/comEC) [Acinetobacter baumannii ACICU]
MFKIILLGWIGGIALMGIDFPLIMQYEKVGEALLLLAFIFYLYKRPMFVDRPFLKAVFCLLCTTSLFMVGYHYAEKALIE
RLEQRETDTRNLDIIVYINRLSEEKDNKVQQTAQVLNFSKEPVNWLLYLKSNNQNLLKNNQNLELGHYYRISGKTRPAHS
YATPGAFDQEKWFIQRNIMSGFNVRYIEPLSLDEIYRLGYQQHLKEQQSFSNSFRLNIEKLRLTFRQILNSSSLQQKGLI
LALLTGDESLLSDETQLQFKQLGISHLLAISGPHVLIFAIMLSWACHQFISRYYPQIYLWKPKQVLMAVPCCLGVLIYTA
FVGFEIPALRTLLSAFIFIGFLLLKQPIKPFTLLVYSASLLLLIDPFSVLSAGFWLSYGACFILLRIYQTIAQLPEQQFL
SLSSKMIFMGKVLIESQGKIFIALSPLTLLFFQQISWVAPLTNIIAVPIVGGVIVPLNIMAACAWFIVKPFGNMLFHFND
MLLSILLSCLGLLEKLSLPLQGISLTPLSLLAISFAIIILFLPKGILPKTWGILCCLPLVIMNKTSQQIQLNILDVGQGQ
AIFLQHSEQNWLIDTGGSYDEKIFSIGQNVVVPFLRQQGVRQLDHVVLSHLDQDDHSGAFPLIQQEIPVKQLISNEQLPN
DLKQPFQYCHQGQQWHYPELDIQILWPKEKDLAFVASNQNQYSCVVYLQFKKVGGYQNFLIMGDAGWEAEYELLKDYPNL
KIDVLVLGHHGSKHSSAYDFLATLKPKLAIASAGFDNRYGHPSQQVIARLKALHIPLKSTVEQGTLSFVLENHKIVLHDR
RLDRLWLSRGF

Nucleotide

• Length: 2436 bp

>NTDB_id=306449 DMO12_RS14505 WP_000472704.1 3023447..3025882(-) (comA/comEC) [Acinetobacter baumannii ACICU]
ATGTTTAAGATTATTCTATTGGGGTGGATTGGCGGTATTGCATTGATGGGAATAGATTTCCCTTTAATCATGCAATATGA
AAAAGTGGGCGAGGCTCTACTGTTACTTGCCTTTATTTTTTATCTTTATAAACGACCAATGTTCGTTGATCGACCATTTT
TAAAGGCAGTGTTTTGCTTATTATGTACAACAAGTCTTTTTATGGTTGGTTACCACTATGCTGAAAAAGCACTGATTGAA
CGATTAGAACAAAGAGAAACGGATACCCGAAATCTCGACATTATTGTTTATATAAACCGTTTAAGTGAAGAAAAAGATAA
TAAGGTTCAACAAACTGCACAAGTTCTAAATTTTTCTAAAGAACCGGTGAATTGGTTGCTATATTTAAAAAGTAATAATC
AAAATTTATTAAAGAATAATCAGAATCTTGAATTAGGTCACTATTATCGAATATCTGGAAAAACAAGACCTGCGCATAGT
TATGCCACCCCAGGAGCTTTTGATCAGGAAAAATGGTTTATTCAGCGAAATATTATGTCTGGTTTTAATGTGAGATATAT
TGAGCCTTTAAGTCTCGATGAAATCTATCGATTGGGCTATCAGCAACATTTAAAAGAACAACAGTCTTTTTCCAATAGTT
TTCGTTTAAATATAGAAAAACTTCGCTTAACTTTTAGGCAAATATTAAACAGCTCATCTCTACAGCAAAAGGGTTTAATT
TTAGCTTTGCTGACAGGTGATGAAAGCCTTTTATCAGATGAAACTCAACTACAGTTCAAACAATTAGGAATTAGTCATTT
ATTGGCGATCTCAGGCCCACATGTGCTCATTTTTGCCATTATGTTATCTTGGGCATGTCATCAATTTATCAGTCGTTATT
ATCCTCAAATTTACTTATGGAAACCGAAACAGGTTTTGATGGCTGTACCATGCTGCCTTGGTGTTTTAATTTATACTGCA
TTTGTAGGTTTCGAAATTCCTGCACTACGAACATTATTATCAGCATTTATATTTATTGGATTTCTATTATTAAAACAACC
TATTAAACCTTTTACATTACTCGTATATAGCGCAAGTCTACTGTTGCTAATTGACCCGTTTAGTGTGCTTTCTGCAGGTT
TTTGGCTGTCTTATGGGGCATGCTTTATTTTATTAAGAATTTACCAAACTATAGCGCAGCTACCTGAGCAACAGTTTTTA
AGTCTGAGCTCAAAAATGATTTTTATGGGTAAGGTGTTAATTGAGTCTCAAGGCAAAATATTTATTGCATTGAGTCCCTT
AACCTTACTTTTCTTTCAACAAATTTCTTGGGTTGCTCCATTAACCAATATTATTGCCGTGCCTATTGTTGGTGGTGTTA
TTGTCCCTTTAAACATCATGGCTGCTTGCGCATGGTTTATAGTAAAACCGTTTGGAAATATGCTTTTTCATTTCAATGAT
ATGTTGCTCAGCATATTGCTGAGTTGTTTGGGCTTATTAGAAAAACTCTCTTTACCATTACAAGGTATAAGCTTGACGCC
ACTGTCTTTATTAGCGATTAGTTTTGCCATAATTATTTTATTTTTACCTAAAGGAATTCTGCCCAAAACTTGGGGGATAT
TATGTTGTTTACCCTTAGTTATTATGAACAAAACGAGTCAACAAATTCAGCTTAATATTTTAGATGTTGGACAGGGGCAA
GCCATTTTTTTACAACATTCCGAACAAAACTGGTTAATTGATACAGGCGGTTCTTACGATGAAAAAATATTTAGTATTGG
ACAAAATGTTGTAGTGCCTTTTCTACGTCAGCAAGGCGTAAGACAATTAGATCATGTTGTGCTATCCCATCTTGATCAAG
ACGACCATAGTGGCGCGTTTCCTCTTATTCAACAAGAGATTCCTGTAAAGCAGCTTATTTCGAATGAACAATTACCAAAT
GATTTAAAGCAACCATTCCAATATTGCCATCAAGGGCAACAATGGCATTATCCTGAGTTAGATATTCAAATTTTATGGCC
TAAAGAAAAAGATCTGGCTTTTGTTGCTTCTAACCAGAATCAATATTCTTGTGTTGTATATCTTCAATTTAAAAAAGTTG
GTGGTTACCAAAATTTTCTTATTATGGGCGATGCAGGATGGGAAGCCGAATACGAGTTATTAAAAGATTATCCTAACTTG
AAGATAGATGTGTTGGTGCTAGGGCATCATGGAAGTAAGCACAGTTCGGCTTATGATTTCTTGGCGACCTTAAAACCTAA
ACTGGCCATTGCATCGGCAGGGTTTGATAACCGTTATGGCCATCCTAGCCAACAAGTTATAGCACGTTTAAAAGCTCTAC
ATATTCCGCTAAAAAGCACTGTGGAACAAGGGACCTTAAGTTTTGTGTTGGAAAATCACAAAATAGTTTTACATGACCGA
CGTTTGGATAGGCTCTGGTTGAGTAGAGGTTTTTAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (33-188)

• Metallo-beta-lactamase superfamily (Lactamase_B) (555-640)

• Competence protein (Competence) (243-521)

3D structure

• AlphaFold DB: A0A7U3Y2A4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/comEC	Acinetobacter baumannii D1279779	97.904	100	0.979
comA/comEC	Acinetobacter baumannii strain A118	96.917	100	0.969
comA/comEC	Acinetobacter baylyi ADP1	50.185	100	0.503