Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ETT50_RS02610 Genome accession   NZ_CP035449
Coordinates   500129..500770 (+) Length   213 a.a.
NCBI ID   WP_032465159.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm56     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 495129..505770
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT50_RS02590 (ETT50_02590) - 495685..496425 (+) 741 WP_002983660.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ETT50_RS02595 (ETT50_02595) pknB 496422..498320 (+) 1899 WP_032465160.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ETT50_RS02600 (ETT50_02600) liaF 498443..499135 (+) 693 WP_011054833.1 cell wall-active antibiotics response protein LiaF -
  ETT50_RS02605 (ETT50_02605) - 499132..500136 (+) 1005 WP_002991890.1 sensor histidine kinase -
  ETT50_RS02610 (ETT50_02610) vraR 500129..500770 (+) 642 WP_032465159.1 response regulator transcription factor Regulator
  ETT50_RS02615 (ETT50_02615) - 500807..502207 (+) 1401 WP_023079249.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ETT50_RS02620 (ETT50_02620) - 502207..502584 (+) 378 WP_030126860.1 S1 RNA-binding domain-containing protein -
  ETT50_RS02625 (ETT50_02625) cysK 502602..503543 (-) 942 WP_032465158.1 cysteine synthase A -
  ETT50_RS02630 (ETT50_02630) - 503671..504303 (-) 633 WP_009880468.1 YigZ family protein -
  ETT50_RS02635 (ETT50_02635) comFA/cflA 504359..505684 (+) 1326 WP_032465157.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23723.38 Da        Isoelectric Point: 5.0119

>NTDB_id=302971 ETT50_RS02610 WP_032465159.1 500129..500770(+) (vraR) [Streptococcus pyogenes strain emm56]
MSKIKVILVDDHEMVRMGLKSFLNLQADIDVVGEASNGREGVDLALALKPDVLVMDLVMPELGGVEATLEVLKKWKEAKV
LVLTSYLDNEKIYPVIDAGAKGYMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFQHHLVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=302971 ETT50_RS02610 WP_032465159.1 500129..500770(+) (vraR) [Streptococcus pyogenes strain emm56]
ATGAGTAAGATAAAAGTGATATTGGTCGATGATCATGAAATGGTCCGCATGGGACTCAAGAGTTTTTTGAATTTACAAGC
TGATATTGATGTCGTTGGTGAGGCCTCTAATGGACGTGAAGGGGTTGATTTGGCATTGGCTTTGAAGCCAGATGTTTTGG
TTATGGATCTAGTGATGCCAGAGTTAGGCGGTGTTGAGGCAACTTTAGAAGTCCTAAAAAAATGGAAAGAGGCTAAGGTA
CTTGTGTTAACTTCCTATCTAGATAATGAAAAGATATACCCTGTCATTGATGCAGGAGCGAAGGGTTATATGTTAAAAAC
ATCGAGTGCGGCTGAAATTTTAAATGCCATTCGCAAGGTTTCAAAGGGAGAGTTAGCTATTGAAACAGAAGTTGACAAAA
AAATTAAGGCGCATGATCAACACCCTGACTTGCATGAGGAACTAACAGCGCGTGAGTATGATATTTTACACCTTTTAGCT
AAAGGGTATGATAATCAGACCATCGCTGATGAACTCTTTATTTCCTTAAAAACCGTCAAAACACATGTGTCCAATATTCT
AGCCAAGTTAGAAGTTGATGACCGAACCCAAGCGGTTGTCTATGCTTTTCAACACCATTTAGTCCCCCAAGACGATAATT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.398

96.714

0.516
  degU Bacillus subtilis subsp. subtilis str. 168

36.283

100

0.385

Multiple sequence alignment