Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   EQH37_RS07630 Genome accession   NZ_CP035243
Coordinates   1526657..1527334 (-) Length   225 a.a.
NCBI ID   WP_000548959.1    Uniprot ID   Q9S1K2
Organism   Streptococcus pneumoniae strain TVO_1901946     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1521657..1532334
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH37_RS07605 (EQH37_08030) - 1521843..1522458 (-) 616 Protein_1527 NAD(P)-dependent oxidoreductase -
  EQH37_RS07610 - 1522697..1523060 (+) 364 Protein_1528 hypothetical protein -
  EQH37_RS07615 (EQH37_08050) - 1523317..1523640 (+) 324 WP_000422776.1 MazG-like protein -
  EQH37_RS07620 (EQH37_08055) thrS 1523698..1525641 (+) 1944 WP_000608349.1 threonine--tRNA ligase -
  EQH37_RS07625 (EQH37_08060) - 1525690..1526664 (-) 975 WP_000887953.1 HAMP domain-containing histidine kinase -
  EQH37_RS07630 (EQH37_08065) braR 1526657..1527334 (-) 678 WP_000548959.1 response regulator transcription factor Regulator
  EQH37_RS07635 (EQH37_08070) - 1527490..1528563 (+) 1074 WP_001273826.1 DUF2974 domain-containing protein -
  EQH37_RS07640 (EQH37_08075) - 1528654..1528956 (-) 303 WP_000281613.1 hypothetical protein -
  EQH37_RS07645 (EQH37_08080) - 1529025..1529462 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  EQH37_RS07650 (EQH37_08085) - 1529538..1530380 (-) 843 WP_000160934.1 metallophosphoesterase -
  EQH37_RS07655 (EQH37_08090) - 1530492..1531142 (+) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  EQH37_RS07660 (EQH37_08100) - 1531321..1531998 (+) 678 WP_000260184.1 nicotinamide mononucleotide transporter family protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=295772 EQH37_RS07630 WP_000548959.1 1526657..1527334(-) (braR) [Streptococcus pneumoniae strain TVO_1901946]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=295772 EQH37_RS07630 WP_000548959.1 1526657..1527334(-) (braR) [Streptococcus pneumoniae strain TVO_1901946]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369

Multiple sequence alignment