Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   SK637_RS01200 Genome accession   NZ_CP028415
Coordinates   241244..241723 (+) Length   159 a.a.
NCBI ID   WP_033688066.1    Uniprot ID   -
Organism   Streptococcus mitis strain SK637     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 236244..246723
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SK637_RS01175 (SK637_00233) - 236985..237860 (-) 876 WP_080710443.1 RluA family pseudouridine synthase -
  SK637_RS01180 (SK637_00234) pbp2a 237947..240142 (+) 2196 WP_033688060.1 penicillin-binding protein PBP2A -
  SK637_RS01185 rpmG 240195..240347 (+) 153 WP_033688062.1 50S ribosomal protein L33 -
  SK637_RS01190 (SK637_00235) secE 240357..240533 (+) 177 WP_001210990.1 preprotein translocase subunit SecE -
  SK637_RS01195 (SK637_00236) nusG 240587..241123 (+) 537 WP_000376740.1 transcription termination/antitermination protein NusG -
  SK637_RS01200 (SK637_00237) comX/sigX/comX2/sigX2 241244..241723 (+) 480 WP_033688066.1 hypothetical protein Regulator

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 20101.89 Da        Isoelectric Point: 9.1161

>NTDB_id=284682 SK637_RS01200 WP_033688066.1 241244..241723(+) (comX/sigX/comX2/sigX2) [Streptococcus mitis strain SK637]
MFKELYKEVQGIVYKSRKEYYLHLWELSDWDQEGMICLHELISREEELVEDLPRLRKYFKTKFRNRILDHIRKQESQKRR
YDKEPYEEVGEISHRISEGGLWIDDYYLFHETLRDYRNKQSKEKQEELERVLRHERFRGRQRVLRDLRIVFKEFDIRTR

Nucleotide


Download         Length: 480 bp        

>NTDB_id=284682 SK637_RS01200 WP_033688066.1 241244..241723(+) (comX/sigX/comX2/sigX2) [Streptococcus mitis strain SK637]
ATGTTTAAAGAATTGTATAAAGAAGTCCAGGGAATTGTATATAAGAGTAGAAAGGAATATTACTTGCATTTATGGGAGCT
ATCGGATTGGGACCAAGAGGGGATGATTTGCTTGCATGAATTGATTAGTAGAGAAGAAGAGCTAGTAGAAGATCTTCCAC
GCTTACGTAAATATTTCAAAACTAAATTCCGTAATCGCATTTTAGACCATATCCGTAAACAAGAAAGCCAGAAGCGTAGA
TATGATAAAGAACCTTATGAAGAAGTAGGTGAGATTAGTCATCGTATCAGTGAGGGAGGTCTCTGGATAGATGATTATTA
TCTCTTTCATGAGACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAGTTAGAACGCGTCTTAAGAC
ATGAACGCTTCCGAGGGCGTCAAAGAGTATTAAGAGACTTACGTATTGTGTTTAAGGAGTTTGATATCCGTACTCGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

94.34

100

0.943
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

94.937

99.371

0.943
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

93.082

100

0.931
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

92.405

99.371

0.918
  comX/comX1 Streptococcus pneumoniae Rx1

91.139

99.371

0.906
  comX/comX2 Streptococcus pneumoniae D39

91.139

99.371

0.906
  comX/comX1 Streptococcus pneumoniae D39

91.139

99.371

0.906
  comX/comX1 Streptococcus pneumoniae R6

91.139

99.371

0.906
  comX/comX2 Streptococcus pneumoniae R6

91.139

99.371

0.906
  comX/comX2 Streptococcus pneumoniae Rx1

91.139

99.371

0.906
  comX/comX2 Streptococcus pneumoniae TIGR4

90.506

99.371

0.899
  comX/comX1 Streptococcus pneumoniae TIGR4

90.506

99.371

0.899
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

50

98.113

0.491
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

50

98.113

0.491
  comX/sigX Streptococcus mutans UA159

46.405

96.226

0.447
  comX/sigX Streptococcus suis D9

45.752

96.226

0.44
  comX/sigX Streptococcus suis isolate S10

45.752

96.226

0.44
  comX/sigX Streptococcus suis P1/7

45.752

96.226

0.44
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

42.282

93.711

0.396
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

42.282

93.711

0.396
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

42.282

93.711

0.396
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

42.282

93.711

0.396
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

41.447

95.597

0.396
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

41.447

95.597

0.396
  comX Streptococcus salivarius SK126

38.71

97.484

0.377
  comX Streptococcus sobrinus strain NIDR 6715-7

38.961

96.855

0.377
  comX/sigX Streptococcus salivarius strain HSISS4

38.065

97.484

0.371
  comX Streptococcus thermophilus LMG 18311

38.065

97.484

0.371
  comX Streptococcus thermophilus LMD-9

38.065

97.484

0.371

Multiple sequence alignment