Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   D1O36_RS07020 Genome accession   NZ_CP031881
Coordinates   1296442..1298313 (-) Length   623 a.a.
NCBI ID   WP_024009998.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST106     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1291442..1303313
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D1O36_RS06985 (D1O36_07015) rimM 1291847..1292365 (-) 519 WP_011226286.1 ribosome maturation factor RimM -
  D1O36_RS07000 (D1O36_07030) vraR 1293046..1293690 (-) 645 WP_002951384.1 response regulator transcription factor Regulator
  D1O36_RS07005 (D1O36_07035) - 1293680..1294690 (-) 1011 WP_011227402.1 sensor histidine kinase -
  D1O36_RS07010 (D1O36_07040) liaF 1294687..1295384 (-) 698 Protein_1307 cell wall-active antibiotics response protein LiaF -
  D1O36_RS10815 - 1295650..1295805 (-) 156 WP_011226290.1 ion channel -
  D1O36_RS07020 (D1O36_07050) stkP/pknB 1296442..1298313 (-) 1872 WP_024009998.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  D1O36_RS07025 (D1O36_07055) - 1298313..1299050 (-) 738 WP_134973348.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  D1O36_RS07030 (D1O36_07060) rsmB 1299094..1300415 (-) 1322 Protein_1311 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  D1O36_RS07035 (D1O36_07065) fmt 1300405..1301340 (-) 936 WP_002951411.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 67857.68 Da        Isoelectric Point: 6.9480

>NTDB_id=272591 D1O36_RS07020 WP_024009998.1 1296442..1298313(-) (stkP/pknB) [Streptococcus thermophilus strain ST106]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNESVAIKVLRTNYQTDQVAVARFQREARAMTELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKFIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGRAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPFDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHSRDSKVVFDDMTDAKTLPKVDSVSSVGPEKKISPKPSEPTPAP
SKQPREKASLSKKKKNLFSTLLKVLLGFVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKLESAGFKVGDVKEVEND
SVNKGKVIKTDPTAGTMRKEGASIDVYVSSGSKGFTLKNYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDNAKEGEILS
QSSEKNKSFNPKDSKAKIKFRVATPKTITMPDVTGLTVSTAVQTLNSKDISSSSIEYHDYNTGVKLDKSKVPSNTEVLYQ
DPQVGTAVDGTVILYVSVVTKSSSIQQSSSASTTQSPSSTSSSSESSTASSTETATEATHTEQ

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=272591 D1O36_RS07020 WP_024009998.1 1296442..1298313(-) (stkP/pknB) [Streptococcus thermophilus strain ST106]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAATCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGTGTAGCTATTAAGGTGCTACGTACCAATTATCAAACTGATCAGGTTG
CTGTGGCGCGTTTCCAGCGTGAAGCACGTGCCATGACTGAGCTTAGCCATCCGAATATCGTTGCGATTAGAGATATTGGT
GAAGAAGACGGTCAGCAGTTCTTGGTGATGGAGTATGTGGATGGTTCAGACTTGAAGAAATTCATTCAAGACCATGCACC
ATTGTCTAACCAAGATGTTGTGCGTATTATGGGGGAAGTCCTTTCCGCCATGACTCTTGCCCACCAAAAGGGTATTATTC
ACCGTGACCTTAAGCCACAGAACGTTCTATTAACTAAGGATGGTAGAGCTAAGGTTACAGACTTTGGTATCGCAGTAGCA
TTTGCTGAAACCAGCCTGACACAAACTAACTCAATGTTGGGGTCAGTCCATTATTTGTCACCAGAACAGGCACGTGGTTC
TAAAGCCACTATCCAAAGTGATATCTATGCTATGGGGATTATGCTCTTTGAAATGTTGACAGGGCATATCCCTTTTGATG
GCGATAGTGCAGTAACCATTGCACTTCAACATTTCCAAAAGCCCCTGCCATCGATTTTGGCTGAGAACCGTAACGTTCCT
CAAGCTTTAGAAAATGTTGTTATTAGAGCAACTGCTAAAAAGCTTGAAAATCGTTACAACAGCACTTTGGAAATGAGTCG
CGACCTAGTAACTAGTTTGCATCCTAGTCATAGTCGTGATTCTAAGGTAGTTTTTGATGACATGACGGATGCTAAGACCC
TGCCAAAGGTTGATTCAGTTTCATCAGTAGGTCCTGAGAAAAAGATTTCTCCTAAACCATCAGAGCCTACACCGGCTCCA
AGCAAACAACCGAGGGAAAAAGCTTCTCTATCTAAAAAAAAGAAAAATCTCTTTTCAACTCTACTCAAGGTTTTACTAGG
CTTCGTCTTTATAGGAATTATCATTTTTGCCTATCTTGTTTTTACCAATCCTGACAATGTCCAAGTACCAAATGTTGTAG
GTCAAGAGTTGTCAACAGCTCAGACGAAACTTGAAAGTGCAGGCTTTAAGGTTGGCGATGTTAAAGAAGTCGAAAATGAT
TCAGTCAATAAGGGCAAAGTTATCAAGACCGACCCTACAGCTGGGACAATGCGTAAAGAGGGAGCAAGCATTGATGTCTA
TGTTTCTTCTGGTAGCAAAGGTTTCACTCTGAAAAATTACAAGGGGAAAAATTATAAGGATGCCATTGAGGATTTAACCT
CGAATTATGGGGTTTCCGAGGATCAGATCGATATTCAACATGTCGAAGACGATAATGCTAAAGAAGGCGAAATTCTATCT
CAAAGTTCGGAGAAAAACAAGTCCTTCAATCCTAAAGATAGTAAGGCAAAAATCAAGTTTCGTGTGGCAACTCCTAAGAC
TATAACTATGCCTGATGTGACTGGTTTAACTGTCTCGACAGCAGTCCAAACCTTGAATAGTAAAGACATTTCAAGCAGCA
GTATTGAGTATCATGACTATAATACTGGTGTTAAGTTGGATAAGAGTAAGGTACCTAGTAATACAGAGGTCCTTTATCAA
GATCCTCAAGTTGGTACTGCTGTTGATGGCACAGTGATTCTCTATGTTTCAGTCGTAACTAAGAGTTCAAGTATTCAACA
GTCAAGCTCAGCAAGTACGACACAATCGCCGTCATCTACAAGTTCTAGTTCTGAAAGTAGTACAGCTTCTAGTACCGAAA
CAGCTACAGAAGCTACTCACACAGAGCAATAA

Domains

Predicted by InterProScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(508-577)

PASTA domain (PASTA)

(367-429)

PASTA domain (PASTA)

(436-502)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

90.534

93.258

0.844
  pknB Streptococcus mutans UA159

64.522

87.319

0.563
  stkP Streptococcus pneumoniae TIGR4

56.713

80.096

0.454
  stkP Streptococcus pneumoniae D39

56.513

80.096

0.453
  stkP Streptococcus pneumoniae R6

56.513

80.096

0.453
  stkP Streptococcus pneumoniae Rx1

56.313

80.096

0.451

Multiple sequence alignment